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Research Report Archives

2003 Research Report

PLEASE NOTE MOST OF THE REPORTS ARE ADOBE ACROBAT PDF's. SOME OF THE FILES ARE LARGE AND WILL TAKE TIME TO DOWNLOAD ON A SLOW CONNECTION.

Introduction from the Chairman, and Honors and Awards:
Research is Gateway to Healthy Nation 218 kb
Carlos A. Pellegrini, M.D.

Cardiothoracic Surgery

Gabriel S. Aldea, M.D.  Minimizing morbidity of cardiopulmonary bypass 1.1 mb
Riyad Karmy-Jones, M.D.  Indications and outcome following thoracotomy
1 mb
also includes: Traumatic aortic rupture
Lung inflammation
Michael S. Mulligan, M.D. Cytokines and chemokines in direct ischemia reperfusion injury of lung and cardiothoracic transplant rejection 216 kb
Timothy H. Pohlman, M.D. and Edward D. Verrier, M.D.  Cellular and molecular mechanisms of ischemia reperfusion injury 2.7 mb

HMC / Trauma Surgery

Eileen Bulger, M.D.  Immunomodulation of the alveolar macrophage 271 kb
also includes: The cytokine profile of burn patients receiving plasmapheresis
Pre-hospital management of the difficult airway
Rib fracture management
Variations in the care of head injured patients
The use of anabolic steroids in the chronically ventilated surgical patient
Nicole Gibran, M.D. Burn wound repair 301 kb
also includes: Cytokine response to thermal injury
Neuroinflammatory response to wound repair

Gregory J. Jurkovich, M.D. National study on costs and effectiveness of trauma care 300 kb
also includes: Prospective, randomized study of elderly rib fracture management
Impact of trauma system on acute care in rural hospitals
Randomized comparison of ultrasound with DPL in the initial evaluation of blunt trauma
Washington State Trauma Registry and Central Region CQI
Post-traumatic stress disorder in trauma patients
Ronald V. Maier, M.D.  Harborview Injury Prevention and Research Center 312 kb
also includes: Clinical trials in the surgical intensive care unit at Harborview Medical Center
Modulation of the excessive inflammatory response to biomaterials
Elucidation and modulation of the trauma-related macrophage inflammatory response to prevent ARDS, MOFS, and death in the severely injured and septic patient
Charles Mock, M.D., Ph.D. Strengthening trauma systems in developing countries 314 kb
also includes: Crash Injury Research and Engineering Network (CIREN)
Avery B. Nathens, M.D., Ph.D., M.P.H.  Effect of organized systems of trauma care on motor-vehicle crash mortality 241 kb
also includes: Relationship between trauma center volume and outcome
Trauma patient in an urban county hospital: Benefit or burden?
Effect of pre-hospital triage to a Level I trauma center vs. a Level III/IV trauma center
Prospective randomized controlled trial of antioxidant therapy in critically ill surgical patients
Grant O'Keefe, M.D., M.P.H. Pathophysiology of post-injury infection and organ failure
Robert K. Winn, Ph.D.
Ischemia-reperfusion injury 309 kb
also includes: Sepsis (overwhelming infection)
Adult respiratory distress syndrome

Pediatric Surgery

Robert S. Sawin, M.D.  Neuroblastoma in the pediatric patient 256 kb
John Waldhausen, M.D. Surgical treatment review improves children's healing process 230 kb

Plastic Surgery

Loren H. Engrav, M.D.  The cones of skin 276 kb
also includes: The female, red duroc pig as model of hypertrophic scarring
UW burn injury rehabilitation model system
Health outcome for burn survivors
Depression following burns
Time off work following burns
Community integration after burns
Grafting over integra
Excision and grafting of face burns
Richard A. Hopper, M.D.  Cleft lip and palate 8.8 mb
also includes: Syndromic severe midface hypoplasia
Craniosynostosis
F. Frank Isik, M.D.  Wound healing 810 kb

Robotics

Lily C. Chang, M.D.  Introduction of surgical robotics systems 241 kb
also includes: Integration of robotics into the clinical setting
Objective measurements of skill identify a learning curve for robotic surgery
Objective measurement of surgical skill using laparoscopic simulators
Richard Satava, M.D.  Objective assessment of surgical skills 2.7 mb
also includes: Operating room of the future
Mika Sinanan, M.D., Ph.D. Surgical telemedicine: Projection of surgical expertise in the WWAMI region 391 kb

Transplant Service

Christian S. Kuhr, M.D.  Identification of genes responsible for immunologic tolerance 689 kb
also includes: Immunologic tolerance in a large animal model
Lymphocyte development and differentiation: The role of the notch gene

UWMC / General Surgery

David R. Flum, M.D., M.P.H.  Advancing the clinical science of surgery using outcomes research tools 335 kb
Brant Oelschlager, M.D. and Carlos A. Pellegrini, M.D. The Swallowing Center at the University of Washington 1.4 mb

VAPSHCS / General Surgery

Kevin G. Billingsley, M.D.  Surgical oncology at VAPSHCS: Overview 332 kb
also includes: Northern Alliance Cancer Center at VA Puget Sound Health Care System
Outcome studies in pancreatic cancer
Clinical studies in colorectal cancer
Colorectal cancer care among vulnerable patient groups
Lorrie Langdale, M.D. Mechanisms of liver ischemia-reperfusion injury 249 kb
Matthias Stelzner, M.D. Clinical application of intestinal mucosal stem cell transplantation 196 kb

Vascular Surgery

Kirk W. Beach, Ph.D., M.D.  Tissue pulsatility imaging for the detection of solid tumors 1.4 mb
Ultrasound lateral coherence imaging
The effect of doppler angle on doppler velocity waveforms at the femoral bifurcation
Alexander W. Clowes, M.D.
Regulation of vascular smooth muscle cell growth 746 kb
Günter Daum, Ph.D.
Modulation of growth factor signaling in vascular SMCS by oxidative stress 549 kb
Thomas Hatsukami, M.D. Magnetic resonance imaging of the high-risk atherosclerotic plaque 2.5 mb
Ted R. Kohler, M.D. Endovascular therapy 628 kb
also includes: Effect of blood flow on intimal hyperplasia and access graft fairlure
Dialysis access grafts
Daniel F. Leotta, Ph.D. Vein graft surveillance using 3D ultrasound imaging 1.7 mb
also includes: Measurement of abdominal aortic aneurysm with 3D ultrasound
Tumor measurement and localization with 3D imaging
Automated measurement of flow-mediated vessel dilation