11.) What are the differences between Crohn's disease and ulcerative colitis?
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There are differences between Crohn's disease and ulcerative in the history as well as pathology and imaging findings. These differences are summarized as follows:
Feature |  | Crohn's Disease |  | Ulcerative Colitis |
Bleeding |  | Rare |  | More Common |
Pain |  | Moderate to severe |  | Mild to moderate |
Anal lesions |  | Common (>50%) |  | Infrequent (<20%) |
Ileal involvement |  | Common |  | Rare(backwash ileitis) |
Distribution |  | Skip areas |  | Continuous from rectum upwards |
Granulomas |  | Present |  | Absent |
Ulcers |  | Linear, deep, scattered |  | Superficial, universal |
Mucosal appearance |  | Cobblestoning |  | Pseudopolyps |
Toxic megacolon |  | Rare |  | More common |
Internal fistulas |  | Yes |  | No |
Fibrosis |  | Present |  | Absent or minimal |
Risk of carcinoma |  | Uncommon |  | Common |
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