TEMPEL LAB


Publications

Silverstein RS, Tempel BL (2006) Atp2b2, encoding plasma membrane ca(2+)-atpase type 2, exhibits tissue-specific first exon usage in hair cells, neurons, and mammary glands of mice, Neuroscience

Gittleman JX, Tempel BL (2006) Kv1.1 containing channels are critical for temporal precision during spike initiation, J. Neurophysiol.

Keogh BP, Cordes D, Stanberry L, Figler BD, Robbins CA, Tempel BL, Green CG, Emmi A, Maravilla KM, Schwartzkroin PA (Aug-Sep 2005) BOLD-fMRI of PTZ-induced seizures in rats., Epilepsy Research, 66 (1-3), 75-90 pdf

McCullough BJ, Tempel BL (Sep 2004) Haplo-insufficiency revealed in deafwaddler mice when tested for hearing loss and ataxia., Hearing Research, 195 (1-2), 90-102 pdf

Wood JD, Muchinsky SJ, Filoteo AG, Penniston JT, Tempel BL (Jun 2004) Low endolymph calcium concentrations in deafwaddler2J mice suggest that PMCA2 contributes to endolymph calcium maintenance., JARO, 5 (2), 99-110 pdf

Lu Y, Monsivais P, Tempel BL, Rubel EW (Feb 2004) Activity-dependent regulation of the potassium channel subunits Kv1.1 and Kv3.1., Journal of Comparative Neurology, 470 (1), 93-106 pdf

Lopantsev V, Tempel BL, Schwartzkroin PA (Dec 2003) Hyperexcitability of CA3 pyramidal cells in mice lacking the potassium channel subunit Kv1.1., Epilepsia, 44 (12), 1506-12 pdf

Kopp-Scheinpflug C, Fuchs K, Lippe WR, Tempel BL, Rubsamen R (Oct 2003) Decreased temporal precision of auditory signaling in Kcna1-null mice: an electrophysiological study in vivo., J. Neurosci., 23 (27), 9199-207 pdf

Rosowski JJ, Brinsko KM, Tempel BL, Kujawa SG (Sep 2003) The aging of the middle ear in 129S6/SvEvTac and CBA/CaJ mice: measurements of umbo velocity, hearing function, and the incidence of pathology., JARO, 4 (3), 371-83 pdf

Brew HM, Hallows JL, Tempel BL (Apr 2003) Hyperexcitability and reduced low threshold potassium currents in auditory neurons of mice lacking the channel subunit Kv1.1., J. Physiol., 548 (Pt 1), 1-20 pdf

Street VA, Goldy JD, Golden AS, Tempel BL, Bird TD, Chance PF, Mapping of Charcot-Marie-Tooth disease type 1C to chromosome 16p identifies a novel locus for demyelinating neuropathies, American Journal of Human Genetics, 70(1), 244-50, January 2002 pdf

Parkinson NJ, Olsson CL, Hallows JL, McKee-Johnson J, Keogh BP, Noben-Trauth K, Kujawa SG, Tempel BL, Mutant beta-spectrin 4 causes auditory and motor neuropathies in quivering mice, Nature Genetics, 29(1), 61-5, September 2001 pdf

Frankel WN, Taylor L, Beyer B, Tempel BL, White HS, Electroconvulsive thresholds of inbred mouse strains, Genomics, 74(3), 306-12, June 2001 pdf

van Brederode JF, Rho JM, Cerne R, Tempel BL, Spain WJ, Evidence of altered inhibition in layer V pyramidal neurons from neocortex of Kcna1-null mice, Neuroscience, 103(4), 921-9, 2001 pdf

Konrad-Martin D, Norton SJ, Mascher KE, Tempel BL, Effects of PMCA2 mutation on DPOAE amplitudes and latencies in deafwaddler mice, Hearing Research, 151(1-2), 205-220, Jan 2001 pdf

Grigg JJ, Brew HM, Tempel BL, Differential expression of voltage-gated potassium channel genes in auditory nuclei of the mouse brainstem., Hearing Research, 140(1-2), 77-90, 2000 pdf

Rho JM, Szot P, Tempel BL, Schwartzkroin PA, Developmental seizure susceptibility of kv1.1 potassium channel knockout mice., Developmental Neuroscience, 21(3-5), 320-7, November 1999 pdf

Hallows JL, Tempel BL, Expression of Kv1.1, a Shaker-like potassium channel, is temporally regulated in embryonic neurons and glia, Journal of Neuroscience, 18(15), 5682-91, August 1998 pdf

Redell JB, Tempel BL, Multiple promoter elements interact to control the transcription of the potassium channel gene, KCNJ2, Journal of Biological Chemistry, 273(35), 22807-18, August 1998 pdf

Street VA, McKee-Johnson JW, Fonseca RC, Tempel BL, Noben-Trauth K, Mutations in a plasma membrane Ca2 -ATPase gene cause deafness in deafwaddler mice, Nature Genetics, 19(4), 390-4, August 1998 pdf

Allen ML, Koh DS, Tempel BL, Cyclic AMP regulates potassium channel expression in C6 glioma by destabilizing Kv1.1 mRNA, Proceedings of the National Academy of Sciences (USA), 95(13), 7693-8, June 1998 pdf

McKee-Johnson JW, Street VA, Erford SK, Robinson LC, Tempel BL, Physical and genetic maps of the deafwaddler region on distal mouse Chr 6, Genomics, 49(3), 371-7, May 1998 pdf

Smart SL, Lopantsev V, Zhang CL, Robbins CA, Wang H, Chiu SY, Schwartzkroin PA, Messing A, Tempel BL, Deletion of the K(V)1.1 potassium channel causes epilepsy in mice, Neuron, 20(4), 809-19, April 1998 pdf

Smart SL, Bosma MM, Tempel BL, Identification of the delayed rectifier potassium channel, Kv1.6, in cultured astrocytes, Glia, 20(2), 127-34, June 1997 pdf

Street VA, Bosma MM, Demas VP, Regan MR, Lin DD, Robinson LC, Agnew WS, Tempel BL, The type 1 inositol 1,4,5-trisphosphate receptor gene is altered in the opisthotonos mouse, Journal of Neuroscience, 17(2), 635-45, January 1997 pdf

Wang H, Allen M L, Grigg J J, Noebels J L, Tempel BL, Hypomyelination alters K+ channel expression in mouse mutants shiverer and Trembler., Neuron, 15(6), 1337-47, December 1995 pdf

Street V A, Robinson L C, Erford S K, Tempel BL, Molecular genetic analysis of distal mouse chromosome 6 defines gene order and positions of the deafwaddler and opisthotonos mutations., Genomics, 29(1), 123-30, 1 Sep 1995 pdf

Tempel BL, Hopkins W F, Potassium channels at nodes of Ranvier: a role in disease?, Society of General Physiologists Series, 50, 41-52, 1995 pdf

Hopkins W F, Allen M L, Houamed K M, Tempel BL, Properties of voltage-gated K+ currents expressed in Xenopus oocytes by mKv1.1, mKv1.2 and their heteromultimers as revealed by mutagenesis of the dendrotoxin-binding site in mKv1.1., Pflügers archiv. European Journal of Physiology, 428(3-4), 382-90, October 1994 pdf

Wang H, Kunkel D D, Schwartzkroin P A, Tempel BL, Localization of Kv1.1 and Kv1.2, two K channel proteins, to synaptic terminals, somata, and dendrites in the mouse brain., Journal of Neuroscience, 14(8), 4588-99, August 1994 pdf

Lock L F, Gilbert D J, Street V A, Migeon M B, Jenkins N A, Copeland N G, Tempel BL, Voltage-gated potassium channel genes are clustered in paralogous regions of the mouse genome., Genomics, 20(3), 354-62, April 1994 pdf

Hopkins W F, Demas V, Tempel B L, Both N- and C-terminal regions contribute to the assembly and functional expression of homo- and heteromultimeric voltage-gated K+ channels., Journal of Neuroscience, 14(3 Pt 1), 1385-93, March 1994 pdf

Bosma M M, Allen M L, Martin T M, Tempel B L, PKA-dependent regulation of mKv1.1, a mouse Shaker-like potassium channel gene, when stably expressed in CHO cells., Journal of Neuroscience, 13(12), 5242-50, December 1993 pdf

Wang H, Kunkel D D, Martin T M, Schwartzkroin P A, Tempel B L, Heteromultimeric K+ channels in terminal and juxtaparanodal regions of neurons., Nature, 365(6441), 75-9, 2 Sep 1993 pdf

Newland C F, Adelman J P, Tempel B L, Almers W, Repulsion between tetraethylammonium ions in cloned voltage-gated potassium channels., Neuron, 8(5), 975-82, May 1992 pdf

Migeon M B, Street V A, Demas V P, Tempel BL, Cloning, sequence and chromosomal localization of MK6, a murine potassium channel gene., Epilepsy research. Supplement, 9, 173-80; discussion 1, 1992 pdf

Rehm H, Tempel BL, Voltage-gated K+ channels of the mammalian brain., Faseb Journal, 5(2), 164-70, February 1991 pdf

Chandy K G, Williams C B, Spencer R H, Aguilar B A, Ghanshani S, Tempel BL, Gutman G A, A family of three mouse potassium channel genes with intronless coding regions., Science, 247(4945), 973-5, 23 Feb 1990 pdf

Rehm H, Newitt RA, Tempel BL, Immunological evidence for a relationship between the dendrotoxin-binding protein and the mammalian homologue of the Drosophila Shaker K channel, Febs Letters, 249(2), 224-8, June 1989 pdf

Tempel BL, Jan YN, Jan LY, Cloning of a probable potassium channel gene from mouse brain, Nature, 332(6167), 837-9, April 1988 pdf

Schwarz TL, Tempel BL, Papazian DM, Jan YN, Jan LY, Multiple potassium-channel components are produced by alternative splicing at the Shaker locus in Drosophila [published erratum appears in Nature 1988 Apr 21;332(6166):740], Nature, 331(6152), 137-42, January 1988 pdf

Timpe LC, Schwarz TL, Tempel BL, Papazian DM, Jan YN, Jan LY, Expression of functional potassium channels from Shaker cDNA in Xenopus oocytes, Nature, 331(6152), 143-5, January 1988 pdf

Papazian DM, Schwarz TL, Tempel BL, Jan YN, Jan LY, Cloning of genomic and complementary DNA from Shaker, a putative potassium channel gene from Drosophila, Science, 237(4816), 749-53, August 1987 pdf

Tempel BL, Papazian DM, Schwarz TL, Jan YN, Jan LY, Sequence of a probable potassium channel component encoded at Shaker locus of Drosophila, Science, 237(4816), 770-5, August 1987 pdf

 

 
 
 

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