2004 TRIO ThinkQuest Semifinalists
| State | Institution & Program | Site Title |
| CA | Calif. State University, Chico Upward Bound | Young And Pregnant |
| CA | Calif. State U., Chico Upward Bound | Fishing in Northern California |
| CA | CSU Monterey Bay Upward Bound |
The United Farm Workers Union |
| CA | San Diego State U. Upward Bound | Breast Cancer |
| CA | San Diego State U. Upward Bound | Colon Cancer |
| CA | San Diego State U. Upward Bound | Ewings Sarcoma |
| CA | San Diego State U. Upward Bound | Hepatic Cancer |
| CA | San Diego State U. Upward Bound | Lung Cancer |
| CA | San Diego State U. Upward Bound | Prostate Cancer |
| FL | Florida A& M University UB Math/Science |
Battle Rap |
| FL | Florida A& M University UB Math/Science |
Death of Innocence |
| FL | Florida A& M University UB Math/Science |
Geochemistry |
| FL | Florida National College Upward Bound |
The Learning Gamer |
| GA | Georgia State University Talent Search |
Operation: School Violence |
| HI | Windward Community College, Upward Bound | Flyin' High |
| IL | Carl Sandburg College Upward Bound |
Dreams |
| IL | Carl Sandburg College Upward Bound |
Teen Drug Use |
| KY | Berea College Upward Bound |
Frisbee: The Ultimate Challenge |
| KY | Berea College Upward Bound |
The Utimate Aritists Of Berea |
| NY | Harlem Center for Education, Talent Search | Immigration in the United States |
| OR | Portland State University Upward Bound |
Acupuncture |
| OR | Portland State University Upward Bound |
History of Togo & Oromia |
| OR | Portland State University Upward Bound |
Pregnant Teens |
| PA | Lincoln University Upward Bound |
Dream |
| SC | University of South Carolina, Upward Bound | Chemotherapy and Cancer |
| SD | University of South Dakota, UBMS | Diggin' Deeper |
| WA | Big Bend Community College | Grand Coulee Dam |
| WA | University of Washington Upward Bound |
Footsteps to Identity: African American Women |
| WA | University of Washington Upward Bound |
The Time of the Crusades and After |
| WI | Marquette University Upward Bound |
The Mysteries Of E. Coli |