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Clinical Trials

Clinical Trials are carefully controlled studies that are conducted in humans who volunteer to test the effectiveness and safety of new drugs, medical products or techniques.

Cranberry: Interactions with Anti-infectious Agents

PI: Gail Anderson, PhD
Co-investigator: Richard W. Grady, MD
Agency: NCCAM / NIH
Type: R21
Period: 1/15/04 – 1/05/07

Evaluation of orally ingested cranberry and antibiotic interactions in the urinary tract.

Evaluation of Continence in a Spina Bifida Population

PI: Kathryn Smith, MSN, PhD
Co-investigator: Richard W. Grady, MD
Agency: Centers for Disease Control
Period: Aug 2005 – July 2008

Prostate Cancer Clinical Trials

Hormones, Nutrients, and Gene Expression in Prostate Tissue

PI: Daniel Lin, MD
Sponsor: Intramural
Period: 2003-present

Selenium and Vitamin E Cancer Prevention Trial (SELECT)

PI: Daniel Lin, MD
Sponsor: SWOG
Period: 2003-present

Cancer of the Prostate Strategic Urologic Research Endeavor (CaPSURE)

PI: Daniel Lin, MD
Sponsor: TAP Pharmaceuticals, Inc.
Period: 2003-present

Brachytherapy Tissue Repository & Registry

PI: Daniel Lin, MD
Sponsor: Intramural
Period: 2004-present

Prevention of Lung Function Decline with Vitamin E and Selenium: Respiratory Ancillary Study to SELECT

PI: Daniel Lin, MD
Sponsor: SWOG
Period: 2004-present

In Vivo Molecular Effects of Aspirin on Prostate Tissue

PI: Daniel Lin, MD
Sponsor: NIH/NIDDK
Period: 2005-present

 

Prospective, Randomized, Controlled, Multicenter Trail of the Memokath 044TW Thermo-Expandable Stent for Maintaining Urethral Patency in Patients after Dilation of Internal Urethrotomy of Recurrent Stricture of the Bulbar Urethra

PI: Hunter Wessells, MD

Type: MVU20020001U, Engineers and Doctors, Inc. 1/1/05-12/30/07

The purpose of the study is to determine whether a novel stent is more effective than control in preventing stricture recurrence after internal urethrotomy.

Detection of Bladder Cancer by Microsatellite Analysis of Urinary Sediment: Multi-Institutional Study

PI: Hunter Wessells, MD

Type: MSA STUDY, Johns Hopkins University 9/1/06-8/31/07

The purpose of the study is to determine whether MSA can detect incident or recurrent superficial bladder cancer.

 

Multidisciplinary Approach to the Study of Chronic Pelvic Pain (MAPP)
University of Washington Discovery Center

To help better understand the underlying causes of the two most prominent chronic urological pain syndromes—interstitial cystitis/painful bladder syndrome (IC/PBS) and chronic prostatitis/chronic pelvic pain syndrome (CP/CPPS)—the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) of the National Institutes of Health (NIH), has launched a new and novel research study.

The NIDDK’s Multidisciplinary Approach to the Study of Chronic Pelvic Pain (MAPP) Research Network embraces a systemic—or whole-body—approach in the study of IC/PBS and CP/CPPS. In addition to moving beyond traditional bladder- and prostate-specific research directions, MAPP Network scientists are investigating potential relationships between these two urological syndromes and other chronic conditions that are sometimes seen in IC/PBS and CP/CPPS patients, such as irritable bowel syndrome, fibromyalgia, and chronic fatigue syndrome.

The University of Washington Discovery Center includes the following members from the Department of Urology: John N. Krieger, MD, Jane L. Miller, MD, and Claire C. Yang, MD. We are actively recruiting persons with chronic urologic pelvic pain, particularly those with symptoms less than 2 years in duration. If you are interested, please contact T.J. Sundsvold at (206) 616-4497.

For further information, go to the study website: http://www.mappnetwork.org


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