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Daniel W. Lin, MD
Professor
Chief of Urologic Oncology
Bridges Endowed Professorship in Prostate Cancer Research
Department of Urology
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Curriculum Vitae
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Profile
English Urologic Oncology
Scope of Care Common conditions treated: All urologic oncology diseases such as prostate cancer, kidney cancer, testis cancer, and bladder cancer. Rare urologic and pelvic cancers.
Common surgeries performed: Radical prostatectomy, complex radical and partial nephrectomy (open and laparoscopic), retroperitoneal lymph node dissection (primary and post-chemotherapy), and radical cystectomy with urinary diversions.
Education & Training
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B.S. Stanford University M.D. Vanderbilt University Urology Residency, University of Washington Urologic Oncology Fellowship, Memorial Sloan-Kettering Cancer Center Research Fellowship, Fred Hutchinson Cancer Research Center
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| Certification Board Name |
Specialty |
Year Certified |
| American Board of Urology |
Urology |
2003 |
Selected Publications
- Page ST, Lin DW, Mostaghel EA, Marck BT, Wright JL, Wu J, Amory JK, Nelson PS, Matsumoto AM "Dihydrotestosterone administration does not increase intraprostatic androgen concentrations or alter prostate androgen action in healthy men: a randomized-controlled trial." The Journal of clinical endocrinology and metabolism 2011 Feb; 96; 2; 430-7
- Zeliadt SB, Hoffman RM, Etzioni R, Gore JL, Kessler LG, Lin DW "Influence of Publication of US and European Prostate Cancer Screening Trials on PSA Testing Practices." Journal of the National Cancer Institute 2011 Feb; ; ;
- Wright JL, Neuhouser ML, Lin DW, Kwon EM, Feng Z, Ostrander EA, Stanford JL "AMACR polymorphisms, dietary intake of red meat and dairy and prostate cancer risk." The Prostate 2011 Apr; 71; 5; 498-506
- Wright JL, Page ST, Lin DW, Stanford JL "Male pattern baldness and prostate cancer risk in a population-based case-control study." Cancer epidemiology 2010 Apr; 34; 2; 131-5
- Wright JL, Dalkin BL, True LD, Ellis WJ, Stanford JL, Lange PH, Lin DW "Positive surgical margins at radical prostatectomy predict prostate cancer specific mortality." The Journal of urology 2010 Jun; 183; 6; 2213-8
- Wright JL, Kwon EM, Lin DW, Kolb S, Koopmeiners JS, Feng Z, Ostrander EA, Stanford JL "CYP17 polymorphisms and prostate cancer outcomes." The Prostate 2010 Jul; 70; 10; 1094-101
- Risk MC, Knudsen BS, Coleman I, Dumpit RF, Kristal AR, Lemeur N, Gentleman RC, True LD, Nelson PS, Lin DW "Differential gene expression in benign prostate epithelium of men with and without prostate cancer: evidence for a prostate cancer field effect." Clinical cancer research : an official journal of the American Association for Cancer Research 2010 Nov; 16; 22; 5414-23
- Newcomb LF, Brooks JD, Carroll PR, Feng Z, Gleave ME, Nelson PS, Thompson IM, Lin DW "Canary Prostate Active Surveillance Study: design of a multi-institutional active surveillance cohort and biorepository." Urology 2010 Feb; 75; 2; 407-13
- Lin DW "Beyond PSA: utility of novel tumor markers in the setting of elevated PSA." Urologic oncology 2009 May-Jun ; 27; 3; 315-21
- Risk MC, Lin DW "New and novel markers for prostate cancer detection." Current urology reports 2009 May; 10; 3; 179-86
- Wu JD, Lin DW, Page ST, Lundgren AD, True LD, Plymate SR "Oxidative DNA damage in the prostate may predispose men to a higher risk of prostate cancer." Translational oncology 2009 Mar; 2; 1; 39-45
- Morgan TM, Lange PH, Porter MP, Lin DW, Ellis WJ, Gallaher IS, Vessella RL "Disseminated tumor cells in prostate cancer patients after radical prostatectomy and without evidence of disease predicts biochemical recurrence." Clinical cancer research : an official journal of the American Association for Cancer Research 2009 Jan; 15; 2; 677-83
- Schenk JM, Neuhouser ML, Lin DW, Kristal AR "A dietary intervention to elicit rapid and complex dietary changes for studies investigating the effects of diet on tissues collected during invasive surgical procedures." Journal of the American Dietetic Association 2009 Mar; 109; 3; 459-63
- Lin DW, Porter M, Montgomery B "Treatment and survival outcomes in young men diagnosed with prostate cancer: a Population-based Cohort Study." Cancer 2009 Jul; 115; 13; 2863-71
- Wright JL, Lin DW "Genetics: Prostate cancer risk stratification by genotype and PSA." Nature reviews. Urology 2009 Dec; 6; 12; 641-2
- Pomerantz MM, Beckwith CA, Regan MM, Wyman SK, Petrovics G, Chen Y, Hawksworth DJ, Schumacher FR, Mucci L, Penney KL, Stampfer MJ, Chan JA, Ardlie KG, Fritz BR, Parkin RK, Lin DW, Dyke M, Herman P, Lee S, Oh WK, Kantoff PW, Tewari M, McLeod DG, Srivastava S, Freedman ML "Evaluation of the 8q24 prostate cancer risk locus and MYC expression." Cancer research 2009 Jul; 69; 13; 5568-74
- Wright JL, Salinas CA, Lin DW, Kolb S, Koopmeiners J, Feng Z, Stanford JL "Prostate cancer specific mortality and Gleason 7 disease differences in prostate cancer outcomes between cases with Gleason 4 + 3 and Gleason 3 + 4 tumors in a population based cohort." The Journal of urology 2009 Dec; 182; 6; 2702-7
- Lin DW "Editorial comment." The Journal of urology 2009 Dec; 182; 6; 2720
- Sim HG, Telesca D, Culp SH, Ellis WJ, Lange PH, True LD, Lin DW "Tertiary Gleason pattern 5 in Gleason 7 prostate cancer predicts pathological stage and biochemical recurrence." The Journal of urology 2008 May; 179; 5; 1775-9
- Wright JL, Lin DW, Porter MP "The association between extent of lymphadenectomy and survival among patients with lymph node metastases undergoing radical cystectomy." Cancer 2008 Jun; 112; 11; 2401-8
- Lin DW "Editorial comment on: marked gene transcript level alterations occur early during radical prostatectomy." European urology 2008 Feb; 53; 2; 345-6
- Wright JL, Morgan TM, Lin DW "Primary scrotal cancer: disease characteristics and increasing incidence." Urology 2008 Nov; 72; 5; 1139-43
- Wright JL, Lin DW, Cowan JE, Carroll PR, Litwin MS "Quality of life in young men after radical prostatectomy." Prostate cancer and prostatic diseases 2008 ; 11; 1; 67-73
- Porter MP, Lin DW "Trends in renal cancer surgery and patient provider characteristics associated with partial nephrectomy in the United States." Urologic oncology 2007 Jul-Aug ; 25; 4; 298-302
- Mostaghel EA, Montgomery RB, Lin DW "The basic biochemistry and molecular events of hormone therapy." Current urology reports 2007 May; 8; 3; 224-32
- Lin DW "Does RPLND improve outcomes in men with intermediate-risk and high-risk germ cell tumors?" Nature clinical practice. Urology 2007 Dec; 4; 12; 654-5
- Sim HG, Lange PH, Lin DW "Role of post-chemotherapy surgery in germ cell tumors." The Urologic clinics of North America 2007 May; 34; 2; 199-217; abstract ix
- Mostaghel EA, Page ST, Lin DW, Fazli L, Coleman IM, True LD, Knudsen B, Hess DL, Nelson CC, Matsumoto AM, Bremner WJ, Gleave ME, Nelson PS "Intraprostatic androgens and androgen-regulated gene expression persist after testosterone suppression: therapeutic implications for castration-resistant prostate cancer." Cancer research 2007 May; 67; 10; 5033-41
- Lin DW, Neuhouser ML, Schenk JM, Coleman IM, Hawley S, Gifford D, Hung H, Knudsen BS, Nelson PS, Kristal AR "Low-fat, low-glycemic load diet and gene expression in human prostate epithelium: a feasibility study of using cDNA microarrays to assess the response to dietary intervention in target tissues." Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 2007 Oct; 16; 10; 2150-4
- Wright JL, Black PC, Brown GA, Porter MP, Kamat AM, Dinney CP, Lin DW "Differences in survival among patients with sarcomatoid carcinoma, carcinosarcoma and urothelial carcinoma of the bladder." The Journal of urology 2007 Dec; 178; 6; 2302-6; discussion 2307
- Page ST, Lin DW, Mostaghel EA, Hess DL, True LD, Amory JK, Nelson PS, Matsumoto AM, Bremner WJ "Persistent intraprostatic androgen concentrations after medical castration in healthy men." The Journal of clinical endocrinology and metabolism 2006 Oct; 91; 10; 3850-6
- Page ST, Plymate SR, Bremner WJ, Matsumoto AM, Hess DL, Lin DW, Amory JK, Nelson PS, Wu JD "Effect of medical castration on CD4+ CD25+ T cells, CD8+ T cell IFN-gamma expression, and NK cells: a physiological role for testosterone and/or its metabolites." American journal of physiology. Endocrinology and metabolism 2006 May; 290; 5; E856-63
- Wright JL, Higano CS, Lin DW "Intermittent androgen deprivation: clinical experience and practical applications." The Urologic clinics of North America 2006 May; 33; 2; 167-79, vi
- Swartz MA, Porter MP, Lin DW, Weiss NS "Incidence of primary urethral carcinoma in the United States." Urology 2006 Dec; 68; 6; 1164-8
- Wright JL, Porter MP, Li CI, Lange PH, Lin DW "Differences in survival among patients with urachal and nonurachal adenocarcinomas of the bladder." Cancer 2006 Aug; 107; 4; 721-8
- Walsh TJ, Grady RW, Porter MP, Lin DW, Weiss NS "Incidence of testicular germ cell cancers in U.S. children: SEER program experience 1973 to 2000." Urology 2006 Aug; 68; 2; 402-5; discussion 405
- Wright JL, Lin DW, Dewan P, Montgomery RB "Tumor lysis syndrome in a patient with metastatic, androgen independent prostate cancer." International journal of urology : official journal of the Japanese Urological Association 2005 Nov; 12; 11; 1012-3
- Zecha G, Lin DW, Montgomery RB "The increasing role of CAM in prostate cancer." JAAPA : official journal of the American Academy of Physician Assistants 2004 Mar; 17; 3; 37-40, 43-4
- Lin DW, Nelson PS "The role of cyclooxygenase-2 inhibition for the prevention and treatment of prostate carcinoma." Clinical prostate cancer 2003 Sep; 2; 2; 119-26
- Swanson KR, True LD, Lin DW, Buhler KR, Vessella R, Murray JD "A quantitative model for the dynamics of serum prostate-specific antigen as a marker for cancerous growth: an explanation for a medical anomaly." The American journal of pathology 2001 Jun; 158; 6; 2195-9
- Lin DW, Santucci RA, Mayo ME, Lange PH, Mitchell ME "Urodynamic evaluation and long-term results of the orthotopic gastric neobladder in men." The Journal of urology 2000 Aug; 164; 2; 356-9
- Lin DW, Thorning DR, Krieger JN "Primary penile lymphoma: diagnostic difficulties and management options." Urology 1999 Aug; 54; 2; 366
- Lin DW, Bush WH, Mayo ME "Endourological treatment of ureteroenteric strictures: efficacy of Acucise endoureterotomy." The Journal of urology 1999 Sep; 162; 3 Pt 1; 696-8
- Lin DW, Kuhr CS, Marsh CL "Endoscopic treatment of bladder outlet obstruction in men after pancreas transplantation." The Journal of urology 1999 Aug; 162; 2; 335-8
- Lin DW, Gold MH, Ransom S, Ellis WJ, Brawer MK "Transition zone prostate specific antigen density: lack of use in prediction of prostatic carcinoma." The Journal of urology 1998 Jul; 160; 1; 77-81; discussion 81-2
- Lin DW, Noteboom JL, Blumenstein BA, Ellis WJ, Lange PH, Vessella RL "Serum percent free prostate-specific antigen in metastatic prostate cancer." Urology 1998 Sep; 52; 3; 366-71
Awards & Honors
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