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Center for Clinical and Epidemiological Research (CCER)

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Chronic Fatigue/Chronic Pain Publications in Refereed Journals

1.         Buchwald D, Sullivan JL, Komaroff AL. Frequency of "chronic active Epstein-Barr virus infection" in a general medical practice. JAMA. 1987;257:2303-2307.

2.         Buchwald D, Goldenberg DL, Sullivan JL, Komaroff AL. The "chronic, active Epstein-Barr virus infection" syndrome and primary fibromyalgia. Arthritis Rheum. 1987;30:1132-1136.

3.         Caligiuri M, Murray C, Buchwald D, Levine H, Cheney P, Peterson D, Komaroff AL, Ritz J. Phenotypic and functional deficiency of natural killer cells in patients with chronic fatigue syndrome. J Immunol. 1987;139:3306-3313.

4.         Buchwald D, Sullivan JL, Leddy S, Komaroff AL. "Chronic Epstein-Barr virus infection" syndrome and polymyalgia rheumatica. J Rheumatol. 1988;15:479-482.

5.         Buchwald D, Freedman AS, Ablashi DV, Sullivan JL, Caligiuri M, Weinberg DS, Hall CG, Ashley RL, Saxinger C, Balanchandran N, Ritz J, Nadler LM, Komaroff AL. A chronic "postinfectious" fatigue syndrome associated with benign lymphoproliferation, B-cell proliferation, and active replication of human herpesvirus-6. J Clin Immunol. 1990;10:335-344.

6.         Katon WJ, Buchwald DS, Simon GE, Russo JE, Mease PJ. Psychiatric illness in patients with chronic fatigue and those with rheumatoid arthritis. J Gen Intern Med. 1991;6:277-285.

7.         Buchwald D, Blair J, Mease P. Treatment of chronic fatigue syndrome with acupuncture. Int J Clin Acup. 1991;2:231-236.

8.         Buchwald D, Wener MH, Komaroff AL. Anti-neuronal antibodies in chronic fatigue syndrome patients with neurologic abnormalities. Arthritis Rheum. 1991;34:1485-1486.

9.         Komaroff AL, Buchwald D. Symptoms and signs of chronic fatigue syndrome. Rev Infect Dis. 1991;S8-11.

10.     Buchwald D, Komaroff AL. Review of laboratory findings for patients with chronic fatigue syndrome. Rev Infect Dis. 1991 Suppl 1;13:S12-18.

11.     Buchwald D, Garrity D, Pascualy R, Kith P, Ashley RL, Wener MH, Kidd PG, Katon WJ, Russo JE. Chronic fatigue syndrome. Toxicol Ind Health. 1992;8:157-173.

12.     Buchwald D, Cheney PR, Peterson DL, Henry B, Wormsley SB, Geiger A, Ablashi DV, Salahuddin SZ, Saxinger C, Biddle R, Kikinis R, Jolesz FA, Folks T, Balachandran N, Gallo RC, Komaroff AL. A chronic illness characterized by fatigue, neurologic and immunologic disorders, and active human herpesvirus type 6 infection. Ann Intern Med. 1992;116:103-113.

13.     Schluederberg A, Straus SE, Peterson P, Blumenthal S, Komaroff AL, Spring SB, Landay A, Buchwald D. NIH Conference. Chronic fatigue syndrome research. Definition and medical outcome assessment. Ann Intern Med. 1992;117:325-331.

14.     Bates DW, Schmitt W, Buchwald D, Ware NC, Lee J, Thoyer E, Kornish RJ, Komaroff AL. Prevalence of fatigue and chronic fatigue syndrome in a primary care practice. Arch Intern Med. 1993;153:2759-2765.

15.     Buchwald D, Jones J, Levine PH. Summary: clinical and multidisciplinary research on chronic fatigue syndrome. Clin Infect Dis. 1994 Suppl 1;18:S115-116.

16.     Buchwald D, Pascualy R, Bombardier C, Kith P. Sleep disorders in patients with chronic fatigue. Clin Infect Dis. 1994 Suppl 1;18:S68-72.

17.     Bates DW, Buchwald D, Lee J, Kith P, Doolittle T, Umali P, Komaroff AL. A comparison of case definitions of chronic fatigue syndrome. Clin Infect Dis. 1994 Suppl 1;18:S11-15.

18.     Fukuda K, Straus SE, Hickie I, Sharpe MC, Dobbins JG, Komaroff A. The chronic fatigue syndrome: a comprehensive approach to its definition and study. International Chronic Fatigue Syndrome Study Group (Buchwald D, member). Ann Intern Med. 1994;121:953-959.

19.     Buchwald D, Pearlman T, Kith P, Schmaling K. Gender differences in patients with chronic fatigue syndrome. J Gen Intern Med. 1994;9:397-401.

20.     Buchwald D, Garrity D. Comparison of patients with chronic fatigue syndrome, fibromyalgia, and multiple chemical sensitivities. Arch Intern Med. 1994;154:2049-2053.

21.     Russo J, Katon W, Sullivan M, Clark M, Buchwald D. Severity of somatization and its relationship to psychiatric disorders and personality. Psychosomatics. 1994;35:546-556.

22.     Bates DW, Buchwald D, Lee J, Kith P, Doolittle T, Rutherford C, Churchill WH, Schur PH, Wener M, Wybenga D, et al. Clinical laboratory test findings in patients with chronic fatigue syndrome. Arch Intern Med. 1995;155:97-103.

23.     Clark MR, Katon W, Russo J, Kith P, Sintay M, Buchwald D. Chronic fatigue: risk factors for symptom persistence in a 2 ½-year follow-up study. Am J Med. 1995;98:187-195.

24.     Buchwald D, Umali P, Umali J, Kith P, Pearlman T, Komaroff AL. Chronic fatigue and the chronic fatigue syndrome: prevalence in a Pacific Northwest health care system. Ann Intern Med. 1995;123:81-88.

25.     Bombardier CH, Buchwald D. Outcome and prognosis of patients with chronic fatigue versus chronic fatigue syndrome. Arch Intern Med. 1995;155:2105-2110.

26.     Buchwald D, Komaroff AL. Laboratory findings in chronic fatigue syndrome. EOS J Immunol Immunopharmacol. 1995;15:15-19.

27.     Salit IE and the Vancouver Chronic Fatigue Syndrome Consensus Group (Buchwald D, member). The chronic fatigue syndrome: a position paper. J Rheumatol. 1996;23:540-544.

28.     Buchwald D, Pearlman T, Umali J, Schmaling K, Katon W. Functional status in patients with chronic fatigue syndrome, other fatiguing illnesses, and healthy individuals. Am J Med. 1996;101:364-370.

29.     Grant JE, Veldee MS, Buchwald D. Analysis of dietary intake and selected nutrient concentrations in patients with chronic fatigue syndrome. J Am Diet Assoc. 1996;96:383-386.

30.     Buchwald D, Manson SM, Pearlman T, Umali J, Kith P. Race and ethnicity in patients with chronic fatigue. J Chron Fatigue Syndr. 1996;2:53-66.

31.     Buchwald D, Umali J, Stene M. Insulin-like growth factor-I (somatomedin C) levels in chronic fatigue syndrome and fibromyalgia. J Rheumatol. 1996;23:739-742.

32.     Buchwald D, Umali J, Pearlman T, Kith P, Ashley R, Wener M. Postinfectious chronic fatigue: a distinct syndrome? Clin Infect Dis. 1996;23;385-387.

33.     Bombardier C, Buchwald D. Chronic fatigue, chronic fatigue syndrome, and fibromyalgia: disability and health-care use. Med Care. 1996;34:924-930.

34.     Buchwald D, Ashley RL, Pearlman T, Kith P, Komaroff AL. Viral serologies in patients with chronic fatigue and chronic fatigue syndrome. J Med Virol. 1996;50:25-30.

35.     Konstantinov K, von Mikecz A, Buchwald D, Jones J, Gerace L, Tan EM. Autoantibodies to nuclear envelope antigens in chronic fatigue syndrome. J Clin Invest. 1996;98:1888-1896.

36.     Buchwald D. Fibromyalgia and chronic fatigue syndrome: similarities and differences. Rheum Dis Clin North Am. 1996;22:219-243.

37.     Buchwald D, Pearlman T, Kith P, Katon W, Schmaling K. Screening for psychiatric disorders in chronic fatigue and chronic fatigue syndrome. J Psychosom Res. 1997;42:87-94.

38.     von Mikecz A, Konstantinov K, Buchwald DS, Gerace L, Tan EM. High frequency of autoantibodies to insoluble cellular antigens in patients with chronic fatigue syndrome. Arthritis Rheum. 1997;40:295-305.

39.     Bennett AL, Chao CC, Hu S, Buchwald D, Fagioli LR, Schur PH, Peterson PK, Komaroff AL. Elevation of bioactive transforming growth factor-beta in serum from patients with chronic fatigue syndrome. J Clin Immunol. 1997;17:160-166.

40.     Buchwald D, Wener MH, Pearlman T, Kith P. Markers of inflammation and immune activation in chronic fatigue and chronic fatigue syndrome. J Rheumatol. 1997;24:372-376.

41.     Shaver JL, Lentz M, Landis CA, Heitkemper MM, Buchwald DS, Woods NF. Sleep, psychological distress, and stress arousal in women with fibromyalgia. Res Nurs Health. 1997;20:247-257.

42.     Komaroff AL, Buchwald DS. Chronic fatigue syndrome: an update. Annu Rev Med. 1998;49:1-13.

43.     Russo J, Katon W, Clark M, Kith P, Sintay M, Buchwald D. Longitudinal changes associated with improvement in chronic fatigue patients. J Psychosom Res. 1998;45:67-76.

44.     Rea T, Russo J, Katon W, Ashley RL, Buchwald D. A prospective study of tender points and fibromyalgia during and after an acute viral infection. Arch Intern Med. 1999;159:865-870.

45.     Buchwald D, Herrell R, Ashton S, Belcourt M, Schmaling K, Goldberg J. The Chronic Fatigue Twin Registry: method of construction, composition, and zygosity assignment. Twin Res. 1999;2:203-211.

46.     Aaron LA, Burke MM, Buchwald D. Overlapping conditions among patients with chronic fatigue syndrome, fibromyalgia, and temporomandibular disorder. Arch Intern Med. 2000;160:221-227.

47.     Afari N, Eisenberg DM, Herrell R, Goldberg J, Kleyman E, Ashton S, Buchwald D. Use of alternative treatments by chronic fatigue syndrome discordant twins. Integr Med. 2000;2:97-103.

48.     Schmaling KB, Smith WR, Buchwald DS. Significant other responses are associated with fatigue and functional status among patients with chronic fatigue syndrome. Psychosom Med. 2000;62:444-450.

49.     Afari N, Schmaling KB, Herrell R, Hartman S, Goldberg J, Buchwald DS. Coping strategies in twins with chronic fatigue and chronic fatigue syndrome. J Psychosom Res. 2000;48:547-554.

50.     Poole J, Herrell R, Ashton S, Goldberg J, Buchwald D. Results of isoproterenol tilt table testing in monozygotic twins discordant for chronic fatigue syndrome. Arch Intern Med. 2000;160:3461-3468.

51.     Aaron LA, Buchwald D. Fibromyalgia and other unexplained clinical conditions. Curr Rheumatol Rep. 2001;3:116-122.

52.     Aaron LA, Buchwald D. A review of the evidence for overlap among unexplained clinical conditions. Ann Intern Med. 2001;134:868-881.

53.     Landis CA, Lentz MJ, Rothermel J, Riffle SC, Chapman D, Buchwald D, Shaver JL. Decreased nocturnal levels of prolactin and growth hormone in women with fibromyalgia. J Clin Endocrinol Metab. 2001;86:1672-1678.

54.     Aaron LA, Herrell R, Ashton S, Belcourt M, Schmaling K, Goldberg J, Buchwald D. Comorbid clinical conditions in chronic fatigue: a co-twin control study. J Gen Intern Med. 2001;16:24-31.

55.     Claypoole K, Mahurin R, Fischer ME, Goldberg J, Schmaling KB, Schoene RB, Ashton S, Buchwald D. Cognitive compromise following exercise in monozygotic twins discordant for chronic fatigue syndrome: fact or artifact? Appl Neuropsychol. 2001;8:31-40.

56.     Lewis DH, Mayberg HS, Fischer ME, Goldberg J, Ashton S, Graham MM, Buchwald D. Monozygotic twins discordant for chronic fatigue syndrome: regional cerebral blood flow SPECT. Radiology. 2001;219:766-773.

57.     Hardt J, Buchwald D, Wilks D, Sharpe M, Nix WA, Egle UT. Health-related quality of life in patients with chronic fatigue syndrome: an international study. J Psychosom Res. 2001;51:431-444.

58.     Buchwald D, Herrell R, Ashton S, Belcourt M, Schmaling K, Sullivan P, Neale M, Goldberg J. A twin study of chronic fatigue. Psychosom Med. 2001;63:936-943.

59.     Roy-Byrne P, Afari N, Ashton S, Fischer M, Goldberg J, Buchwald D. Chronic fatigue and anxiety/depression: a twin study. Br J Psychiatry. 2002;180;29-34.

60.     Sabath DE, Barcy S, Koelle DM, Zeh J, Ashton S, Buchwald D. Cellular immunity in monozygotic twins discordant for chronic fatigue syndrome. J Infect Dis. 2002;185:828-832.

61.     Herrell R, Goldberg J, Hartman S, Belcourt M, Schmaling K, Buchwald D. Chronic fatigue and chronic fatigue syndrome: a co-twin control study of functional status. Qual Life Res. 2002;11:463-471.

62.     Sullivan PF, Smith W, Buchwald D. Latent class analysis of symptoms associated with chronic fatigue syndrome and fibromyalgia. Psychol Med. 2002;32:881-888.

63.     Koelle DM, Barcy S, Huang ML, Ashley RL, Corey L, Zeh J, Ashton S, Buchwald D. Markers of viral infection in monozygotic twins discordant for chronic fatigue syndrome. Clin Infect Dis. 2002;35:518-525.

64.     Aaron LA, Arguelles LM, Ashton S, Belcourt M, Herrell R, Goldberg J, Smith WR, Buchwald D. Health and functional status of twins with chronic regional and widespread pain. J Rheumatol. 2002;29:2426-2434.

65.     Schmaling KB, Lewis DH, Fiedelak JI, Mahurin R, Buchwald DS. Single-photon emission computerized tomography and neurocognitive function in patients with chronic fatigue syndrome. Psychosom Med. 2003;65:129-136.

66.     Assefi NP, Coy TV, Uslan D, Buchwald D. Financial, occupational, and personal consequences of disability in patients with chronic fatigue syndrome and fibromyalgia compared to other fatiguing conditions. J Rheumatol. 2003;30:804-808.

67.     Watson NF, Kapur V, Arguelles LM, Goldberg J, Schmidt DF, Armitage R, Buchwald D. Comparison of subjective and objective measures of insomnia in monozygotic twins discordant for chronic fatigue syndrome. Sleep. 2003;26:324-328.

68.     Landis CA, Frey CA, Lentz MJ, Rothermel J, Buchwald D, Shaver JL. Self-reported sleep quality and fatigue correlates with actigraphy in midlife women with fibromyalgia. Nurs Res. 2003;52:140-147.

69.     Reeves WC, Lloyd A, Vernon SD, Klimas N, Jason LA, Bleijenberg G, Evengard B, White PD, Nisenbaum R, Unger ER; International Chronic Fatigue Syndrome Study Group (D. Buchwald, member). Identification of ambiguities in the 1994 chronic fatigue syndrome research case definition and recommendations for resolution. BMC Health Serv Res. 2003;3:25-33.

70.     Schmaling KB, Fiedelak JI, Katon WJ, Bader JO, Buchwald DS. Prospective study of the prognosis of unexplained chronic fatigue in a clinic-based cohort. Psychosom Med. 2003;65:1047-1054.

71.     Afari N, Buchwald D. Chronic fatigue syndrome: a review. Am J Psychiatry. 2003;160: 221-236.

72.     Holdcraft LC, Assefi N, Buchwald D. Complementary and alternative medicine in fibromyalgia and related syndromes. Best Pract Res Clin Rheumatol. 2003;17:667-683.

73.     Aaron LA, Buchwald D. Chronic diffuse musculoskeletal pain, fibromyalgia and co-morbid unexplained clinical conditions. Best Pract Res Clin Rheumatol. 2003;17:563-574.

74.     Ball N, Buchwald DS, Schmidt D, Goldberg J, Ashton S, Armitage R. Monozygotic twins discordant for chronic fatigue syndrome: objective measures of sleep. J Psychosom Res. 2004;56:207-212.

75.     Mahurin RK, Claypoole KH, Goldberg JH, Arguelles L, Ashton S, Buchwald D. Cognitive processing in monozygotic twins discordant for chronic fatigue syndrome. Neuropsychology. 2004;18:232-239.

76.     Roy-Byrne P, Smith WR, Goldberg J, Afari N, Buchwald D. Post-traumatic stress disorder among patients with chronic pain and chronic fatigue. Psychol Med. 2004;34:363-368.

77.     Landis CA, Lentz MJ, Tsuji J, Buchwald D, Shaver JL. Pain, psychological variables, sleep quality, and natural killer cell activity in midlife women with and without fibromyalgia. Brain Behav Immun. 2004;18:304-313.

78.     Landis CA, Lentz MJ, Rothermel J, Buchwald D, Shaver JL. Decreased sleep spindles and spindle activity in midlife women with fibromyalgia and pain. Sleep. 2004;27:741-750.

79.     Watson NF, Jacobsen C, Goldberg J, Kapur V, Buchwald D. Subjective and objective sleepiness in monozygotic twins discordant for chronic fatigue syndrome. Sleep. 2004;27:973-977.

80.     White PD, Thomas JM, Sullivan PF, Buchwald D. The nosology of sub-acute and chronic fatigue syndromes that follow infectious mononucleosis. Psychol Med. 2004;34:499-507.

81.     Fitzpatrick AL, Reed T, Goldberg J, Buchwald D. The association between prolonged fatigue and cardiovascular disease in World War II veteran twins. Twin Res. 2004;7:571-577.

82.     Buchwald D, Goldberg J, Noonan C, Beals J, Manson S; AI-SUPERPFP Team. Relationship between post-traumatic stress disorder and pain in two American Indian tribes. Pain Med. 2005;6:72-79.

83.     Afari N, van der Meer J, Bleijenberg G, Buchwald D. Chronic fatigue syndrome in practice: an international approach. Psychiatr Ann. 2005;35:350-360.

84.     Assefi NP, Sherman KJ, Jacobsen C, Goldberg J, Smith WR, Buchwald D. A randomized clinical trial of acupuncture compared with sham acupuncture in fibromyalgia. Ann Intern Med. 2005;143:10-19.

85.     Schmaling KB, Fiedelak JI, Bader J, Buchwald D. A longitudinal study of physical activity and body mass index among persons with unexplained chronic fatigue. J Psychosom Res. 2005;58:375-381.

86.     Furberg H, Olarte M, Afari N, Goldberg J, Buchwald D, Sullivan PF. The prevalence of self-reported chronic fatigue in a U.S. twin registry. J Psychosom Res. 2005;59:283-290.

87.     Arguelles LM, Afari N, Buchwald DS, Clauw DJ, Furner S, Goldberg J. A twin study of posttraumatic stress disorder symptoms and chronic widespread pain. Pain. 2006;124:150-157.

88.     Smith WR, Noonan C, Buchwald D. Mortality in a cohort of chronically fatigued patients. Psychol Med. 2006;36:1301-1306.

89.     Smith WR, White PD, Buchwald D. A case control study of premorbid and currently reported physical activity levels in chronic fatigue syndrome. BMC Psychiatry. 2006;6:53.

90.     Schur E, Noonan C, Smith W, Goldberg J, Buchwald D. Body mass index and fatigue severity in chronic fatigue syndrome. J Chronic Fatigue Syndr. 2007;14(1):69-77.

91.     Sherlin L, Budzynski T, Kogan-Budzynski H, Congedo M, Fischer ME, Buchwald D. Low-resolution electromagnetic brain tomography (LORETA) of monozygotic twins discordant for chronic fatigue syndrome. NeuroImage. 2007;34:1438-1442.

92.     Ullrich PM, Afari N, Jacobsen C, Goldberg J, Buchwald D. Cold pressor pain sensitivity in twins discordant for chronic fatigue syndrome. Pain Med. 2007;8:216-222.

93.     Schur EA, Afari N, Furberg H, Olarte M, Goldberg J, Sullivan PF, Buchwald D. Feeling bad in more ways than one: comorbidity patterns of medically unexplained and psychiatric conditions. J Gen Intern Med. 2007;22:818-821.

94.     Claypoole KH, Noonan C, Mahurin RK, Goldberg J, Erickson T, Buchwald D. A twin study of cognitive function in chronic fatigue syndrome: the effects of sudden illness onset. Neuropsychology. 2007;21:507-513.

95.     Armitage R, Landis C, Hoffman R, Lentz M, Watson NF, Goldberg J, Buchwald D. The impact of a 4-hour sleep delay on slow-wave activity in twins discordant for chronic fatigue syndrome. Sleep. 2007;30:657-662.

96.     Jones JF, Kohl KS, Ahmadipour N, Bleijenberg G, Buchwald D, Evengard B, Jason LA, Klimas NG, Lloyd A, McCleary K, Oleske JM, White PD; The Brighton Collaboration Fatigue Working Group. Fatigue: case definition and guidelines for collection, analysis, and presentation of immunization safety data. Vaccine. 2007;25:5685-5696.

97.     Schur E, Afari N, Goldberg J, Buchwald D, Sullivan PF. Twin analyses of fatigue. Twin Res Hum Genet. 2007;10:729-733.

98.     Schur E, Noonan C, Buchwald D. Prospective study of body mass index, weight change,  and fatigue in acute infectious mononucleosis.  J Chronic Fatigue Syndr. 2007;14(3):27-36.

99.     Afari N, Wen Y, Buchwald D, Goldberg J, Plesh O. Are post-traumatic stress disorder symptoms and temporomandibular pain associated? Findings from a community-based twin registry.  J Orofac Pain. (in press).

100.    Jacobsen C, Goldberg J, Nickel R, Buchwald D. Prevalence of chronic pain in a representative sample in the United States. Pain Med. (in press).

101.    Sawchuk CN, Buchwald D. Chronic fatigue syndrome. BMJ, Point of Care Series. (in  press).

102.    Assefi N, Bogart A, Goldberg J, Buchwald D. Reiki for the treatment of fibromyalgia: a randomized controlled trial. J Altern Complement Med. 2008;14:1115-1122. PMID: 18991519

103.    Armitage R, Landis C, Hoffmann R, Lentz M, Watson N, Goldberg J, Buchwald D. Power spectral analysis of sleep EEG in twins discordant for chronic fatigue syndrome. J Psychosom Res. 2009;66:51-57. PMCID: PMC2634600

104.    Hickie I, Davenport T, Vernon SD, Nisenbaum R, Reeves WC, Hadzi-Pavlovic D, Lloyd A; International Chronic Fatigue Syndrome Study Group (Buchwald D, member). Are chronic fatigue and chronic fatigue syndrome valid clinical entities across countries and healthcare settings? Aust N Z J Psychiatry. 2009;43:25-35. PMID: 19085525

105.    Watson N, Buchwald D, Goldberg J, Ellenbogen R, Noonan C. Neurologic signs and symptoms in fibromyalgia. Arthritis Rheum. 2009;60:2839-2844. PMCID: PMC2769083

106.    Smith W, Strachan E, Buchwald D. Coping, self-efficacy, and psychiatric history in patients with both chronic widespread pain and chronic fatigue. Gen Hosp Psych 2009; 31:347-352. PMID: 19555795

107.    Rodriguez MA, Afari N, Buchwald DS; National Institute of Diabetes and Digestive and Kidney Diseases Working Group on Urological Chronic Pelvic Pain. Evidence for overlap between urological and non-urological unexplained clinical conditions. J Urol. 2009;182:2123-2131. PMID: 19758633

108.    Romano J, Jensen M, Schmaling K, Hops H, Buchwald D. Illness behaviors in patients with unexplained chronic fatigue are associated with significant other responses. J Behav Med. 2009;32(6):558-569. PMID: 1991597

109.    Smith M, Buchwald D, Bograt A, Goldberg J, Smith W, Afari N. Adolescent offspring of mothers with chronic fatigue. J Adolesc Health. 2010;46(3):284-291. PMCID: PMC2824612

110.    Johnson Wright L, Schur EK, Noonan C, Ahumada S, Buchwald D, Afari N. Chronic pain, overweight, and obesity: Findings from a community-based twin registry. J Pain. 2010;11(7):628-635.