ISCRM

Quellos High Throughput Screening Core

Frequently Asked Questions


General Questions


Who can use the Quellos High Throughput Screening Core facility?      Answer

If I'm an "Out-of-the-Area" client, what are my options for performing screens at the facility?      Answer

What are the fees for screening? Are there mechanisms for offsetting costs? Is the Core's automation equipment available for use on a "time/usage basis"?      Answer

What initial steps are necessary prior to beginning to screen at the Core facility and how do I gain access?      Answer

What are the functions of the Core's staff?      Answer

Just how long does a typical screening campaign take to complete?      Answer

In anticipation of screening, how far in advance should I fill out an application and make an appointment with the Core's staff?      Answer

Due to unavoidable circumstances, I will have to screen after normal business hours. Will this be possible?      Answer

I'm a screening novice and what's new to me may not be new to others. Are there others that I can contact with previous experience with screening or with my particular assay?      Answer


Chemical (Small Molecule) Screening


With regards to chemical libraries and small molecule screening, "who, what, where, when and how"?      Answer

I've done the screen and secondary assays. How can I obtain another sample of my hit(s)?      Answer


RNA Interference Screening (RNAi, Loss of Function)


With regards to "RNA Interference" screening (loss of function, siRNA, etc.), "who, what, where, when and how"?      Answer


Equipment/Materials/Training


What does the Core facility provide?      Answer

What do I need to purchase? And how much will it cost?      Answer

Aren't all 96/384 well plates the same?      Answer

What equipment is available for screening and how do I choose? Will I be able to receive formal training?      Answer


Miscellaneous


Do Core Staff members wish to be placed on and funded by my Grant? Does the Core facility issue letters of support?      Answer

How should I acknowledge the Quellos High Throughput Screening Core in publications?      Answer

Should the sources for the chemical/biological screening materials be specified?      Answer

With regards to screening within the facility, who does the information/data belong too? Do I as a client have freedom to operate with the "hits" obtained from screening at the Core facility? How does your Core differ from the NIH MLPCN in this regard?      Answer