By providing a number of Core Facilities, the NORC facilitates the integration and coordination of the abundant ongoing activities throughout the UW system. Our overarching goals are to foster new interdisciplinary research collaborations, stimulate new research activities, improve nutrition and obesity education at multiple levels, and facilitate optimal nutritional management of patients.

Core facilities are available for use by Affiliate Investigators, who are broadly dispersed throughout several schools and numerous departments and divisions within the University of Washington.

The University of Washington NORC is supported by the National Institutes of Health, NIDDK, grant # P30 DK035816. Please cite this grant support in your publications if you have utilized NORC facilities for the research.

Recent Publications

Genetic determinants of atherosclerosis, obesity, and energy balance in consomic mice.

Spiezio SH, Amon LM, McMillen TS, Vick CM, Houston BA, Caldwell M, Ogimoto K, Morton GJ, Kirk EA, Schwartz MW, Nadeau JH, LeBoeuf RC. Genetic determinants of atherosclerosis, obesity, and energy balance in consomic mice. Mammalian Genome 25:549-63, 2014. PMCID: PMC4241139

Initial evidence that GLP-1 receptor blockade fails to suppress postprandial satiety or promote food intake in humans.

Melhorn SJ, Tyagi V, Smeraglio A, Roth CL, Schur EA. Initial evidence that GLP-1 receptor blockade fails to suppress postprandial satiety or promote food intake in humans. Appetite 82:85-90, 2014. PMCID: PMC4171349

The apolipoprotein-AI mimetic peptide L4F at a modest dose does not attenuate weight gain, inflammation, or atherosclerosis in LDLR-null mice.

Averill MM, Kim EJ, Goodspeed L, Wang S, Subramanian S, Den Hartigh LJ, Tang C, Ding Y, Reardon CA, Getz GS, Chait A. The apolipoprotein-AI mimetic peptide L4F at a modest dose does not attenuate weight gain, inflammation, or atherosclerosis in LDLR-null mice. PLoS One 9:e109252, 2014. PMCID: PMC4186861

Effects of dietary fat and saturated fat content on liver fat and markers of oxidative stress in overweight/obese men and women under weight-stable conditions.

Marina A, von Frankenberg AD, Suvag S, Callahan HS, Kratz M, Richards TL, Utzschneider KM. Effects of dietary fat and saturated fat content on liver fat and markers of oxidative stress in overweight/obese men and women under weight-stable conditions. Nutrients 6:4678-90, 2014. PMCID: PMC4245556

Control of hepatic glucose metabolism by islet and brain.

Rojas JM, Schwartz MW. Control of hepatic glucose metabolism by islet and brain. Diabetes Obes Metab 1:33-40, 2014. PMCID: PMC4191916

Deletion of serum amyloid A3 improves high fat high sucrose diet-induced adipose tissue inflammation and hyperlipidemia in female mice.

den Hartigh LJ, Wang S, Goodspeed L, Ding Y, Averill M, Subramanian S, Wietecha T, O'Brien KD, Chait A. Deletion of serum amyloid A3 improves high fat high sucrose diet-induced adipose tissue inflammation and hyperlipidemia in female mice. PLoS One, 2014. PMCID: PMC4177399

Upcoming Seminars

04/08


Edward Fisher, MD, PhD New York University Medical Center

Macrophages in many guises during Atherosclerosis Regression

04/22


Jay Taborsky, PhD University of Washington, VA Puget Sound Health Care System

Lessons Gleaned from 40 Years of Studying Paracrine and Neural Control of the Endocrine Pancreas

05/06


Kroc Scholar Morris Birnbaum, MD, PhD Pfizer, Inc.

The Complex Regulation of Hepatic Metabolism

05/13


Dan Rader, MD University of Pennsylvania

Translational Medicine in Lipids and Atherosclerosis

05/28


Annual Symposium

Beta Cell Replacement Therapy for Diabetes