The goal of the UW SCOR is to elucidate the mechanisms by which transporters and enzymes alter maternal and fetal drug exposure during pregnancy. More

Project 1 - P-glycoprotein (P-gp) & Cytochrome P450 3A4/5 (CYP3A4/5)

Project 2 - Breast Cancer Resistance Protein (BCRP, ABCG2)

Project 3 - Organic Cation Transporter 3 (OCT3)

The UW SCOR works closely and synergistically with the UW Obstetrics-Fetal Pharmacology Research Unit (PI: Mary Hebert) whose mission overlaps with that of the UW SCOR

UW SCOR is funded by the NIH Office of Research in Women's Health (ORWH) and the National Institute of Child Health and Human Development (NICHD) Grant # 5P50HD044404.