Rosetta is a molecular modeling software package for understanding protein structures, protein design, protein docking, protein-DNA and protein-protein interactions. The Rosetta software contains multiple functional modules, including Rosetta ab initio, RosettaNMR, RosettaDesign, RosettaDock, Rosetta Fragment Selection, Rosetta Nucleic Acids, RosettaLigand, and more. For a list of current features, see current release notes. The newest Rosetta release is version 3.0 which is a re-write of version 2 and currently contains a subset of functions. Some functions in version 2 have not been transferred.
PyRosetta is a version of Rosetta implemented with a Python interface and developed primarily by Jeffrey Gray's Laboratory at Johns Hopkins University.
Rosetta Commons
The Rosetta software has been developed through collaboration among the participating researchers and institutions of the Rosetta Commons, currently consisting of the University of Washington, University of North Carolina at Chapel Hill, Johns Hopkins University, University of California Santa Cruz, University of California San Francisco, New York University, Fred Hutchinson Cancer Research Center, Vanderbilt University, Rosetta Design Group LLC, Hebrew University, Los Alamos National Lab, IIMCB, Stanford University, University of Kansas, ETH Zurich and Washington University, St. Louis. The Rosetta software is distributed by the University of Washington on behalf of the Rosetta Commons.
Rosetta and PyRosetta are free for research use by users at non-profit and academic institutions. Commercial users need to pay a site license fee to use the software. The current license fee for Rosetta starts at $35,000. Please contact us for information on commercial use of PyRosetta.
