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Research
By exploring the properties of light, tissue, and their interactions, our laboratory invented, discovered or pioneered optical microangiography, full-range complex Fourier domain optical coherence tomography, optical clearing of biological tissue, surface-wave sensing of elastic properties of tissue, phase-sensitive optical coherence vibrometry, multifunctional nanoparticle contrast agents and their applications in imaging tissue morphology, cerebral blood flow, retinal blood perfusion, cochlear blood perfusion, and embryonic heart development. The research topics currently active in the laboratory include:
⃝ Optical Imaging System Developments ⃝ Optical Coherence Tomography ⃝ Time-domain OCT ⃝ Frequency-domain OCT ⃝ Doppler OCT ⃝ Polarization-sensitive OCT ⃝ Whole-field OCT ⃝ Optical coherence elastography ⃝ 3-D optical microangiography (OMAG) ⃝ Photothermal OCT ⃝ Transillumination optical computed tomography ⃝ Photoacoustic Imaging ⃝ Contrast agent development ⃝ Optical Projection Tomography ⃝ Laser-Speckle and Doppler Imaging
⃝ Imaging Applications ⃝ Transcranial imaging for small animal models: Cerebral blood perfusion and tissue morphology ⃝ Imaging of embryonic developments, including chick embryos ⃝ Optical imaging of cochlea in animal models and human: Cochlear blood perfusion and tissue morphology ⃝ Tissue engineering ⃝ Early disease diagnosis based on optical contrasts
⃝ Tissue Optical Clearing |
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Engineering and Physical Sciences Research Council, UK |
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Biotechnology and Biological Sciences research Council, UK |
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Biophotonics and Imaging Laboratory (BAIL) |
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Contact Info Department of Bioengineering , University of Washington, N410 William H. Foege Building [UW map], 3720 15th Ave NE Seattle, WA 98195 Email: wangrk @ u dot washington dot edu , Phone: (206) 616-5025
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