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WYLIE BURKE, MD, PhD
Professor

Office: 1107 NE 45th St, Ste 305
Phone: 206-221-5482
Email: wburke@u.washington.edu

| Recent Publications | Honors, Awards, Grants | Courses | Curriculum Vitae (PDF)

Dr. Wylie Burke is Professor of Bioethics and Humanities at the University of Washington. She is also Principal Investigator of the University of Washington Center for Genomics and Healthcare Equality, an NIH-funded Center of Excellence in Ethical, Legal, and Social Implications (ELSI) Research and dual Principal Investigator of the Northwest-Alaska Pharmacogenomic Research Network. Her research addresses the social, ethical and policy implications of genetic information. 

Dr. Burke received a Ph.D. in Genetics and an M.D. from the University of Washington and completed a residency in Internal Medicine at the University of Washington. She was a Medical Genetics Fellow at the University of Washington from 1981 to 1982. Dr. Burke was a member of the Department of Medicine at the University of Washington from 1983 to 2000, where she served as Associate Director of the Internal Medicine Residency Program from 1988 to 1994 and as founding Director of the University of Washington's Women's Health Care Center from 1994 to 1999. She was appointed Chair of what was then known as the Department of Medical History and Ethics in October 2000 and remained Chair of the re-named Department of Bioethics and Humanitiesuntil 2014. She is also an Adjunct Professor of Medicine.

Recent Publications

  • Boyer BB, Dillard D, Woodahl EL, Whitener R, Thummel KE, Burke W. Ethical issues in developing pharmacogenetic research partnerships with American Indigenous communities. Clin Pharmacol Ther. 2011 Mar;89(3):343-5. [PMC3090734]
  • Burke W, Tarini B, Press N, Evans JP. Genetic screening.  Epidemiol Rev 2011;33(1):148-64. [PMC3166195]
  • Fullerton SM, Knerr S, Burke W. Finding a place for genomics in health disparities research. Public Health Genomics. 2012;15(3-4):156-63. [PMC3685214]
  • Biesecker LG, Burke W, Kohane I, Plon SE, Zimmern R. Next-generation sequencing in the clinic: are we ready?  Nat Rev Genet. 2012 Nov;13(11):818-24.
  • Burke W, Trinidad S, Press N. Essential elements of personalized medicine. Urol Oncol, in press. [NIHMS 547884]
  • Beskow LM, Burke W, Fullerton SM, Sharp RR. Offering aggregate results to participants in genomic research: opportunities and challenges. Genet Med. 2012; 14:490-96.[PMC3612423]
  • Edwards KL, Lemke AA, Trinidad SB, Lewis SM, Starks H, Snapinn KW, Griffin MQ, Wiesner GL, Burke W. Genetics researchers' and IRB professionals' attitudes toward genetic research review: a comparative analysis. Genet Med. 2012; 14-136-42. [PMC3448270]
  • Trinidad SB, Fullerton SM, Bares JM, Jarvik GP, Larson EB, Burke W. Informed consent in genome-scale research: what do prospective participants think? AJOB Primary Research. 2012 Jul;3(3):3-11. [PMC3593675]
  • Kelley M, Edwards K, Starks H, Fullerton SM, James R, Goering S, Holland S, Disis ML, Burke W. Values in translation: how asking the right questions can move translational science toward greater health impact. Clin Transl Sci. 2012 Dec;5(6):445-451.
  • James R, Starks H, Segrest VA, Burke W. From leaky pipeline to irrigation system: minority education through the lens of community-based participatory research. Prog Community Health Partnersh. 2012 Winter;6(4):471-9. [NIHMSID #554110]
  • Lakes KD, Vaughan E, Lemke A, Jones M, Wigal T, Baker D, Swanson JM, Burke W. Maternal perspectives on the return of genetic results: Context matters. Am J Med Genet A. 2013 Jan;161(1):38-47.
  • Clayton EW, Haga S, Kuszler P, Bane E, Shutske K, Burke W.  Managing incidental genomic findings: legal obligations of clinicians.  Genet Med 2013; 15:624-9.
  • Hoeft TJ, Burke W, Hopkins SE, Charles W, Trinidad SB, James RD, Boyer BB. Building partnerships in community-based participatory research: budgetary and other cost considerations. Health Promot Pract. 2013 Apr 30. [Epub ahead of print][NIHMSID457487]
  • Burke W, Matheny Antommaria AH, Bennett R, Botkin J, Clayton EW, Henderson GE, Holm IA, Jarvik GP, Khoury MJ, Knoppers BM, Press NA, Ross LF, Rothstein MA, Saal H, Uhlmann WR, Wilfond B, Wolf SM, Zimmern R. Recommendations for returning genomic incidental findings? We need to talk! Genet Med. 2013 Aug 1. doi: 10.1038/gim.2013.113. [Epub ahead of print] [NIHMSID 525096]
  • Burke W, Trinidad SB, Clayton EW.  Seeking genomic knowledge: the case for clinical restraint.  Hastings Law J 2013; 64: 6:1649-1663. [NIHMSID 559777]

Awards, Honors and Grants Received

  • Elected to the Institute of Medicine (2007)
  • President, American Society of Human Genetics (2007)
  • NHS International Fellow, Public Health Genetics Unit, Cambridge UK (2006)
  • Principal Investigator, Center for Genomics and Healthcare Equality - a Center of Excellence in ELSI Research funded by the National Human Genome Research Institute
  • Dual Principal Investigator, Northwest-Alaska Pharmacogenomics Research Network
  • Named a "Local Legend", (Celebrating America's Local Women Physicians), Washington State

Courses

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