Development and regeneration of synaptic circuits in the vertebrate retina
Our lab is interested in neuronal circuit assembly in development, circuit disassembly in degeneration and circuit reassembly upon cellular regeneration. Our studies are based on the vertebrate retina of zebrafish and mice. We apply a diversity of approaches including in vivo and in vitro confocal and multiphoton imaging, electron microscopy, transgenic methods and electrophysiology to investigate neuronal structure, function and connectivity in normal and perturbed retinas.