{"id":115,"date":"2025-05-29T16:52:34","date_gmt":"2025-05-29T16:52:34","guid":{"rendered":"https:\/\/depts.washington.edu\/breast-imaging-teach\/wordpress\/?p=115"},"modified":"2025-06-30T17:02:11","modified_gmt":"2025-06-30T17:02:11","slug":"case-4","status":"publish","type":"post","link":"https:\/\/depts.washington.edu\/breast-imaging-teach\/?p=115","title":{"rendered":"Case 4"},"content":{"rendered":"<p>Contributed by: Steven J. Rockoff, MD and Diana L. Lam, MD &#8211; June 1, 2020<\/p>\n<div class=\"wp-block-pb-accordion-item c-accordion__item js-accordion-item no-js\" data-initially-open=\"false\" data-click-to-close=\"true\" data-auto-close=\"true\" data-scroll=\"false\" data-scroll-offset=\"0\">\n<h2 id=\"at-1150\" class=\"c-accordion__title js-accordion-controller\" role=\"button\">Question 1<\/h2>\n<div id=\"ac-1150\" class=\"c-accordion__content\">\n<p>A 56-year-old woman presents for a screening mammogram:<\/p>\n<figure class=\"wp-block-image is-resized\"><img loading=\"lazy\" decoding=\"async\" width=\"242\" height=\"300\" src=\"https:\/\/depts.washington.edu\/breast-imaging-teach\/wordpress\/wp-content\/uploads\/2025\/05\/68-MLO-1-242x300.png\" alt=\"\" class=\"wp-image-118\" style=\"width:404px;height:auto\" srcset=\"https:\/\/depts.washington.edu\/breast-imaging-teach\/wordpress\/wp-content\/uploads\/2025\/05\/68-MLO-1-242x300.png 242w, https:\/\/depts.washington.edu\/breast-imaging-teach\/wordpress\/wp-content\/uploads\/2025\/05\/68-MLO-1-375x465.png 375w, https:\/\/depts.washington.edu\/breast-imaging-teach\/wordpress\/wp-content\/uploads\/2025\/05\/68-MLO-1.png 471w\" sizes=\"auto, (max-width: 242px) 100vw, 242px\" \/><\/figure>\n<figure class=\"wp-block-image is-resized\"><img loading=\"lazy\" decoding=\"async\" width=\"246\" height=\"300\" src=\"https:\/\/depts.washington.edu\/breast-imaging-teach\/wordpress\/wp-content\/uploads\/2025\/05\/68-CC-246x300.png\" alt=\"\" class=\"wp-image-119\" style=\"width:404px;height:auto\" srcset=\"https:\/\/depts.washington.edu\/breast-imaging-teach\/wordpress\/wp-content\/uploads\/2025\/05\/68-CC-246x300.png 246w, https:\/\/depts.washington.edu\/breast-imaging-teach\/wordpress\/wp-content\/uploads\/2025\/05\/68-CC-375x458.png 375w, https:\/\/depts.washington.edu\/breast-imaging-teach\/wordpress\/wp-content\/uploads\/2025\/05\/68-CC.png 459w\" sizes=\"auto, (max-width: 246px) 100vw, 246px\" \/><\/figure>\n<p>How do you best describe the patient\u2019s breast density?<\/p>\n<p>A. The breasts are almost entirely fatty<\/p>\n<p>B. There are scattered areas of fibroglandular density<\/p>\n<p>C. The breasts are heterogeneously dense<\/p>\n<p>D. The breasts are extremely dense<\/p>\n<div class=\"wp-block-pb-accordion-item c-accordion__item js-accordion-item no-js\" data-initially-open=\"false\" data-click-to-close=\"true\" data-auto-close=\"true\" data-scroll=\"false\" data-scroll-offset=\"0\">\n<h4 id=\"at-1151\" class=\"c-accordion__title js-accordion-controller\" role=\"button\">Answer<\/h4>\n<div id=\"ac-1151\" class=\"c-accordion__content\">\n<p><strong>C. The breasts are heterogeneously dense<\/strong><\/p>\n<p><strong>Explanation:&nbsp;<\/strong>One of the first steps in interpreting a mammogram is assessing the breast composition, also known as breast density. There are four acceptable categories described in the ACR BI-RADS manual, which are listed above. This patient\u2019s breasts are heterogeneously dense on mammogram, which may obscure small masses.<\/p>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<div class=\"wp-block-pb-accordion-item c-accordion__item js-accordion-item no-js\" data-initially-open=\"false\" data-click-to-close=\"true\" data-auto-close=\"true\" data-scroll=\"false\" data-scroll-offset=\"0\">\n<h2 id=\"at-1152\" class=\"c-accordion__title js-accordion-controller\" role=\"button\">Question 2<\/h2>\n<div id=\"ac-1152\" class=\"c-accordion__content\">\n<p>A representative zoomed in image is shown here:<\/p>\n<figure class=\"wp-block-image\"><img loading=\"lazy\" decoding=\"async\" width=\"294\" height=\"300\" src=\"https:\/\/depts.washington.edu\/breast-imaging-teach\/wordpress\/wp-content\/uploads\/2025\/05\/68-vascular-calcs-294x300.png\" alt=\"\" class=\"wp-image-121\" srcset=\"https:\/\/depts.washington.edu\/breast-imaging-teach\/wordpress\/wp-content\/uploads\/2025\/05\/68-vascular-calcs-294x300.png 294w, https:\/\/depts.washington.edu\/breast-imaging-teach\/wordpress\/wp-content\/uploads\/2025\/05\/68-vascular-calcs-375x383.png 375w, https:\/\/depts.washington.edu\/breast-imaging-teach\/wordpress\/wp-content\/uploads\/2025\/05\/68-vascular-calcs.png 495w\" sizes=\"auto, (max-width: 294px) 100vw, 294px\" \/><\/figure>\n<p>What is the dominant type of calcification that is present?<\/p>\n<p>A. Fine pleomorphic calcifications<\/p>\n<p>B. Large rod-like calcifications<\/p>\n<p>C. Vascular calcifications<\/p>\n<p>D. Linear calcifications<\/p>\n<div class=\"wp-block-pb-accordion-item c-accordion__item js-accordion-item no-js\" data-initially-open=\"false\" data-click-to-close=\"true\" data-auto-close=\"true\" data-scroll=\"false\" data-scroll-offset=\"0\">\n<h4 id=\"at-1153\" class=\"c-accordion__title js-accordion-controller\" role=\"button\">Answer<\/h4>\n<div id=\"ac-1153\" class=\"c-accordion__content\">\n<p><strong>C. Vascular calcifications<\/strong><\/p>\n<p><strong>Explanation:&nbsp;<\/strong>These are benign vascular calcifications, present in a diffuse distribution bilaterally. These have the characteristic \u201ctram-track\u201d appearance.<\/p>\n<p>Note that \u201clinear\u201d is not a type of calcification like the other answer choices, but rather is a descriptor for the distribution of calcifications.<\/p>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<div class=\"wp-block-pb-accordion-item c-accordion__item js-accordion-item no-js\" data-initially-open=\"false\" data-click-to-close=\"true\" data-auto-close=\"true\" data-scroll=\"false\" data-scroll-offset=\"0\">\n<h2 id=\"at-1154\" class=\"c-accordion__title js-accordion-controller\" role=\"button\">Question 3<\/h2>\n<div id=\"ac-1154\" class=\"c-accordion__content\">\n<p>Although difficult to appreciate on the 2-D whole breast images provided above, there was a screen-detected mass in the lower inner quadrant of the right breast. Here is the mass noted on MLO and spot tomosynthesis CC images:<\/p>\n<figure class=\"wp-block-image is-resized\"><img loading=\"lazy\" decoding=\"async\" width=\"138\" height=\"300\" src=\"https:\/\/depts.washington.edu\/breast-imaging-teach\/wordpress\/wp-content\/uploads\/2025\/05\/68-MLO-circle-138x300.png\" alt=\"\" class=\"wp-image-124\" style=\"width:540px;height:auto\" srcset=\"https:\/\/depts.washington.edu\/breast-imaging-teach\/wordpress\/wp-content\/uploads\/2025\/05\/68-MLO-circle-138x300.png 138w, https:\/\/depts.washington.edu\/breast-imaging-teach\/wordpress\/wp-content\/uploads\/2025\/05\/68-MLO-circle.png 222w\" sizes=\"auto, (max-width: 138px) 100vw, 138px\" \/><\/figure>\n<figure class=\"wp-block-image is-resized\"><img loading=\"lazy\" decoding=\"async\" width=\"259\" height=\"300\" src=\"https:\/\/depts.washington.edu\/breast-imaging-teach\/wordpress\/wp-content\/uploads\/2025\/05\/68-Spot-CC-tomo-259x300.png\" alt=\"\" class=\"wp-image-123\" style=\"width:540px;height:auto\" srcset=\"https:\/\/depts.washington.edu\/breast-imaging-teach\/wordpress\/wp-content\/uploads\/2025\/05\/68-Spot-CC-tomo-259x300.png 259w, https:\/\/depts.washington.edu\/breast-imaging-teach\/wordpress\/wp-content\/uploads\/2025\/05\/68-Spot-CC-tomo-375x434.png 375w, https:\/\/depts.washington.edu\/breast-imaging-teach\/wordpress\/wp-content\/uploads\/2025\/05\/68-Spot-CC-tomo.png 439w\" sizes=\"auto, (max-width: 259px) 100vw, 259px\" \/><\/figure>\n<p>What is the best descriptor for the margins of this mass on mammogram?<\/p>\n<p>A. Circumscribed<\/p>\n<p>B. Obscured<\/p>\n<p>C. Microlobulated<\/p>\n<p>D. Indistinct<\/p>\n<p>E. Spiculated<\/p>\n<div class=\"wp-block-pb-accordion-item c-accordion__item js-accordion-item no-js\" data-initially-open=\"false\" data-click-to-close=\"true\" data-auto-close=\"true\" data-scroll=\"false\" data-scroll-offset=\"0\">\n<h4 id=\"at-1155\" class=\"c-accordion__title js-accordion-controller\" role=\"button\">Answer<\/h4>\n<div id=\"ac-1155\" class=\"c-accordion__content\">\n<p><strong>E. Spiculated<\/strong><\/p>\n<p><strong>Explanation:&nbsp;<\/strong>The numerous thin lines radiating outward from the mass are indicative of spiculated margins, which is a suspicious finding.<\/p>\n<p>A mass with circumscribed margins has at least 75% of its margins sharply demarcated and separable from the surrounding tissue.<\/p>\n<p>A mass with obscured margins has at least 25% of its margin hidden by superimposed or adjacent breast tissue.<\/p>\n<p>A mass with microlobulated margins has multiple small outward undulations.<\/p>\n<p>A mass with indistinct margins has no clear demarcation of its margin from the surrounding tissue.<\/p>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<div class=\"wp-block-pb-accordion-item c-accordion__item js-accordion-item no-js\" data-initially-open=\"false\" data-click-to-close=\"true\" data-auto-close=\"true\" data-scroll=\"false\" data-scroll-offset=\"0\">\n<h2 id=\"at-1156\" class=\"c-accordion__title js-accordion-controller\" role=\"button\">Question 4<\/h2>\n<div id=\"ac-1156\" class=\"c-accordion__content\">\n<p>Targeted ultrasound was performed, with a representative image of the mass shown here:<\/p>\n<figure class=\"wp-block-image is-resized\"><img loading=\"lazy\" decoding=\"async\" width=\"300\" height=\"210\" src=\"https:\/\/depts.washington.edu\/breast-imaging-teach\/wordpress\/wp-content\/uploads\/2025\/05\/68-US-300x210.png\" alt=\"\" class=\"wp-image-126\" style=\"width:583px;height:auto\" srcset=\"https:\/\/depts.washington.edu\/breast-imaging-teach\/wordpress\/wp-content\/uploads\/2025\/05\/68-US-300x210.png 300w, https:\/\/depts.washington.edu\/breast-imaging-teach\/wordpress\/wp-content\/uploads\/2025\/05\/68-US.png 375w\" sizes=\"auto, (max-width: 300px) 100vw, 300px\" \/><\/figure>\n<p>What is the best descriptor for the margins of this mass on ultrasound?<\/p>\n<p>A. Indistinct<\/p>\n<p>B. Angular<\/p>\n<p>C. Microlobulated<\/p>\n<p>D. Spiculated<\/p>\n<div class=\"wp-block-pb-accordion-item c-accordion__item js-accordion-item no-js\" data-initially-open=\"false\" data-click-to-close=\"true\" data-auto-close=\"true\" data-scroll=\"false\" data-scroll-offset=\"0\">\n<h4 id=\"at-1157\" class=\"c-accordion__title js-accordion-controller\" role=\"button\">Answer<\/h4>\n<div id=\"ac-1157\" class=\"c-accordion__content\">\n<p><strong>A. Indistinct<\/strong><\/p>\n<p><strong>Explanation:&nbsp;<\/strong>This mass is not circumscribed on ultrasound. The margin between the majority of the mass and surrounding tissue is not clearly defined, and there is a lack of other features that would be seen with the other margin descriptors. This mass\u2019s sonographic margin is best described as indistinct.<\/p>\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n<p>Ultrasound-guided biopsy was performed, which yielded invasive ductal carcinoma.<\/p>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n","protected":false},"excerpt":{"rendered":"<p>Contributed by: Steven J. Rockoff, MD and Diana L. Lam, MD &#8211; June 1, 2020<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[6],"tags":[],"class_list":["post-115","post","type-post","status-publish","format-standard","hentry","category-quiz"],"_links":{"self":[{"href":"https:\/\/depts.washington.edu\/breast-imaging-teach\/index.php?rest_route=\/wp\/v2\/posts\/115","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/depts.washington.edu\/breast-imaging-teach\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/depts.washington.edu\/breast-imaging-teach\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/depts.washington.edu\/breast-imaging-teach\/index.php?rest_route=\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/depts.washington.edu\/breast-imaging-teach\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=115"}],"version-history":[{"count":5,"href":"https:\/\/depts.washington.edu\/breast-imaging-teach\/index.php?rest_route=\/wp\/v2\/posts\/115\/revisions"}],"predecessor-version":[{"id":651,"href":"https:\/\/depts.washington.edu\/breast-imaging-teach\/index.php?rest_route=\/wp\/v2\/posts\/115\/revisions\/651"}],"wp:attachment":[{"href":"https:\/\/depts.washington.edu\/breast-imaging-teach\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=115"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/depts.washington.edu\/breast-imaging-teach\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=115"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/depts.washington.edu\/breast-imaging-teach\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=115"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}