{"id":228,"date":"2025-06-03T21:55:38","date_gmt":"2025-06-03T21:55:38","guid":{"rendered":"https:\/\/depts.washington.edu\/breast-imaging-teach\/?p=228"},"modified":"2025-06-30T10:22:53","modified_gmt":"2025-06-30T18:22:53","slug":"case-14","status":"publish","type":"post","link":"https:\/\/depts.washington.edu\/breast-imaging-teach\/?p=228","title":{"rendered":"Case 12"},"content":{"rendered":"<p>Contributed by: Steven J. Rockoff, MD and Diana L. Lam, MD &#8211; June 1, 2020<\/p>\n<div class=\"wp-block-pb-accordion-item c-accordion__item js-accordion-item no-js\">\n<h2 id=\"at-2280\" class=\"c-accordion__title js-accordion-controller\" role=\"button\">Question 1<\/h2>\n<div id=\"ac-2280\" class=\"c-accordion__content\">\n<p>A 40-year-old woman presents for a baseline screening mammogram:<\/p>\n<figure class=\"wp-block-image\"><img loading=\"lazy\" decoding=\"async\" width=\"300\" height=\"210\" src=\"https:\/\/depts.washington.edu\/breast-imaging-teach\/wordpress\/wp-content\/uploads\/2025\/06\/MLO-2-750x524-1-300x210.jpg\" alt=\"\" class=\"wp-image-231\" srcset=\"https:\/\/depts.washington.edu\/breast-imaging-teach\/wordpress\/wp-content\/uploads\/2025\/06\/MLO-2-750x524-1-300x210.jpg 300w, https:\/\/depts.washington.edu\/breast-imaging-teach\/wordpress\/wp-content\/uploads\/2025\/06\/MLO-2-750x524-1-375x262.jpg 375w, https:\/\/depts.washington.edu\/breast-imaging-teach\/wordpress\/wp-content\/uploads\/2025\/06\/MLO-2-750x524-1.jpg 750w\" sizes=\"auto, (max-width: 300px) 100vw, 300px\" \/><\/figure>\n<figure class=\"wp-block-image\"><img loading=\"lazy\" decoding=\"async\" width=\"300\" height=\"201\" src=\"https:\/\/depts.washington.edu\/breast-imaging-teach\/wordpress\/wp-content\/uploads\/2025\/06\/CC-2-750x502-1-300x201.jpg\" alt=\"\" class=\"wp-image-232\" srcset=\"https:\/\/depts.washington.edu\/breast-imaging-teach\/wordpress\/wp-content\/uploads\/2025\/06\/CC-2-750x502-1-300x201.jpg 300w, https:\/\/depts.washington.edu\/breast-imaging-teach\/wordpress\/wp-content\/uploads\/2025\/06\/CC-2-750x502-1-375x251.jpg 375w, https:\/\/depts.washington.edu\/breast-imaging-teach\/wordpress\/wp-content\/uploads\/2025\/06\/CC-2-750x502-1.jpg 750w\" sizes=\"auto, (max-width: 300px) 100vw, 300px\" \/><\/figure>\n<p>You note a large mass in the left breast. What is the best description for the location of this mass?<br \/>A. 1:00 (upper outer quadrant)<br \/>B. 1:00 (upper inner quadrant)<br \/>C. 5:00 (lower outer quadrant)<br \/>D. 5:00 (lower inner quadrant)<br \/>E. 11:00 (upper inner quadrant)<br \/>F. 11:00 (upper outer quadrant)<\/p>\n<div class=\"wp-block-pb-accordion-item c-accordion__item js-accordion-item no-js\">\n<h3 id=\"at-2281\" class=\"c-accordion__title js-accordion-controller\" role=\"button\">Answer<\/h3>\n<div id=\"ac-2281\" class=\"c-accordion__content\">\n<p><strong>A. 1:00 (upper outer quadrant)<\/strong><\/p>\n<p><strong>Explanation:<\/strong>&nbsp;To interpret a mammogram, one must become familiar with the proper way to describe the location of a finding such as a mass or calcifications. Standard reporting should include the following:<\/p>\n<ul class=\"wp-block-list\">\n<li>Laterality (left or right breast)<\/li>\n<li>Quadrant (upper outer, upper inner, lower outer, or lower inner)<\/li>\n<li>O\u2019clock face (i.e. 12:00, 1:00, 2:00, etc\u2026)<\/li>\n<\/ul>\n<p>O\u2019clock face is determined by visualizing that you are standing in front of the patient, looking at the breast with a clock superimposed upon it. Note that any o\u2019clock position will not be in the same quadrant of each breast (i.e. a 2:00 mass in the right breast is upper inner quadrant, but a 2:00 mass in the left breast is upper outer quadrant).<\/p>\n<p>As per the ACR BI-RADS manual, other location descriptors that can be used are:<\/p>\n<ul class=\"wp-block-list\">\n<li>Depth (anterior third, middle third, or posterior third)<\/li>\n<li>Distance from the nipple<\/li>\n<li>A few terms that can be used in lieu of a quadrant: \u201ccentral\u201d, \u201cretroareolar\u201d, \u201caxillary tail\u201d<\/li>\n<\/ul>\n<p>Determining the quadrant and o\u2019clock face of a finding requires being familiar with the standard display of a mammogram. If you are not yet familiar with the orientation of a mammogram, see the below annotations:<\/p>\n<figure class=\"wp-block-image\"><img loading=\"lazy\" decoding=\"async\" width=\"300\" height=\"210\" src=\"https:\/\/depts.washington.edu\/breast-imaging-teach\/wordpress\/wp-content\/uploads\/2025\/06\/MLO-2-1-750x524-1-300x210.jpg\" alt=\"\" class=\"wp-image-233\" srcset=\"https:\/\/depts.washington.edu\/breast-imaging-teach\/wordpress\/wp-content\/uploads\/2025\/06\/MLO-2-1-750x524-1-300x210.jpg 300w, https:\/\/depts.washington.edu\/breast-imaging-teach\/wordpress\/wp-content\/uploads\/2025\/06\/MLO-2-1-750x524-1-375x262.jpg 375w, https:\/\/depts.washington.edu\/breast-imaging-teach\/wordpress\/wp-content\/uploads\/2025\/06\/MLO-2-1-750x524-1.jpg 750w\" sizes=\"auto, (max-width: 300px) 100vw, 300px\" \/><\/figure>\n<figure class=\"wp-block-image\"><img loading=\"lazy\" decoding=\"async\" width=\"300\" height=\"201\" src=\"https:\/\/depts.washington.edu\/breast-imaging-teach\/wordpress\/wp-content\/uploads\/2025\/06\/CC-2-1-750x502-1-300x201.jpg\" alt=\"\" class=\"wp-image-234\" srcset=\"https:\/\/depts.washington.edu\/breast-imaging-teach\/wordpress\/wp-content\/uploads\/2025\/06\/CC-2-1-750x502-1-300x201.jpg 300w, https:\/\/depts.washington.edu\/breast-imaging-teach\/wordpress\/wp-content\/uploads\/2025\/06\/CC-2-1-750x502-1-375x251.jpg 375w, https:\/\/depts.washington.edu\/breast-imaging-teach\/wordpress\/wp-content\/uploads\/2025\/06\/CC-2-1-750x502-1.jpg 750w\" sizes=\"auto, (max-width: 300px) 100vw, 300px\" \/><\/figure>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<div class=\"wp-block-pb-accordion-item c-accordion__item js-accordion-item no-js\">\n<h2 id=\"at-2283\" class=\"c-accordion__title js-accordion-controller\" role=\"button\">Question 2<\/h2>\n<div id=\"ac-2283\" class=\"c-accordion__content\">\n<p>What is your assessment and recommendation after reading the screening mammogram?<br \/>A. BI-RADS 0 (Incomplete); Recommend diagnostic ultrasound<br \/>B. BI-RADS 1 (Negative); Recommend one year follow-up<br \/>C. BI-RADS 2 (Benign); Recommend one year follow-up<br \/>D. BI-RADS 3 (Probably Benign); Recommend six month follow-up<br \/>E. BI-RADS 4 (Suspicious); Recommend biopsy<\/p>\n<div class=\"wp-block-pb-accordion-item c-accordion__item js-accordion-item no-js\">\n<h3 id=\"at-2284\" class=\"c-accordion__title js-accordion-controller\" role=\"button\">Answer<\/h3>\n<div id=\"ac-2284\" class=\"c-accordion__content\">\n<p><strong>A. BI-RADS 0 (Incomplete); Recommend diagnostic ultrasound<\/strong><\/p>\n<p><strong>Explanation:<\/strong>&nbsp;This is the patient\u2019s first (baseline) mammogram and there is a left breast mass in the upper outer quadrant that needs further characterization before deciding final management. Targeted diagnostic ultrasound is the correct next step.<\/p>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<div class=\"wp-block-pb-accordion-item c-accordion__item js-accordion-item no-js\">\n<h2 id=\"at-2285\" class=\"c-accordion__title js-accordion-controller\" role=\"button\">Question 3<\/h2>\n<div id=\"ac-2285\" class=\"c-accordion__content\">\n<p>The ultrasound of the expected position of the mass is performed. A representative image:<\/p>\n<figure class=\"wp-block-image\"><img loading=\"lazy\" decoding=\"async\" width=\"300\" height=\"239\" src=\"https:\/\/depts.washington.edu\/breast-imaging-teach\/wordpress\/wp-content\/uploads\/2025\/06\/US-1-1-300x239.jpg\" alt=\"\" class=\"wp-image-237\" srcset=\"https:\/\/depts.washington.edu\/breast-imaging-teach\/wordpress\/wp-content\/uploads\/2025\/06\/US-1-1-300x239.jpg 300w, https:\/\/depts.washington.edu\/breast-imaging-teach\/wordpress\/wp-content\/uploads\/2025\/06\/US-1-1.jpg 370w\" sizes=\"auto, (max-width: 300px) 100vw, 300px\" \/><\/figure>\n<p>What is your assessment and recommendation?<br \/>A. BI-RADS 0 (Incomplete); Recommend diagnostic MRI<br \/>B. BI-RADS 1 (Negative); One year follow-up<br \/>C. BI-RADS 2 (Benign); One year follow-up<br \/>D. BI-RADS 3 (Probably Benign); Six month follow-up<br \/>E. BI-RADS 4 (Suspicious); Ultrasound-guided biopsy<br \/>F. BI-RADS 5 (Highly Suspicious); Ultrasound-guided biopsy<\/p>\n<div class=\"wp-block-pb-accordion-item c-accordion__item js-accordion-item no-js\">\n<h3 id=\"at-2286\" class=\"c-accordion__title js-accordion-controller\" role=\"button\">Answer<\/h3>\n<div id=\"ac-2286\" class=\"c-accordion__content\">\n<p><strong>D. BI-RADS 3 (Probably Benign); Six month follow-up<\/strong><\/p>\n<figure class=\"wp-block-image\"><img loading=\"lazy\" decoding=\"async\" width=\"300\" height=\"239\" src=\"https:\/\/depts.washington.edu\/breast-imaging-teach\/wordpress\/wp-content\/uploads\/2025\/06\/US-3-annot-300x239.jpg\" alt=\"\" class=\"wp-image-239\" srcset=\"https:\/\/depts.washington.edu\/breast-imaging-teach\/wordpress\/wp-content\/uploads\/2025\/06\/US-3-annot-300x239.jpg 300w, https:\/\/depts.washington.edu\/breast-imaging-teach\/wordpress\/wp-content\/uploads\/2025\/06\/US-3-annot.jpg 370w\" sizes=\"auto, (max-width: 300px) 100vw, 300px\" \/><\/figure>\n<p><strong>Explanation:<\/strong>&nbsp;This non-palpable, solid, circumscribed oval mass can be assessed as \u201cProbably Benign\u201d, meaning that it has a less than a 2% chance of being malignant. The assessment of BI-RADS 3 can be given with a recommendation for short term follow-up (diagnostic ultrasound in six months). Once two years of stability has been documented for this mass, it can finally be designated benign with no specific follow-up needed.<\/p>\n<p>As per the ACR BI-RADS manual 5th edition, there are three mammographic findings which can be designated as BI-RADS 3, Probably Benign:<\/p>\n<ol class=\"wp-block-list\">\n<li>A solid mass which is non-palpable, non-calcified, circumscribed, oval or round\u00a0<strong>(as seen in this case)<\/strong>.<\/li>\n<li>A non-palpable focal asymmetry with no ultrasound correlate.<\/li>\n<li>A solitary group of punctate calcifications.<\/li>\n<\/ol>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<div class=\"wp-block-pb-accordion-item c-accordion__item js-accordion-item no-js\">\n<h2 id=\"at-2287\" class=\"c-accordion__title js-accordion-controller\" role=\"button\">Question 4<\/h2>\n<div id=\"ac-2287\" class=\"c-accordion__content\">\n<p>Maybe you were wondering about the smaller mammographic mass that is posterior to the dominant mass. Here is the ultrasound of that second mass:<\/p>\n<figure class=\"wp-block-image\"><img loading=\"lazy\" decoding=\"async\" width=\"300\" height=\"190\" src=\"https:\/\/depts.washington.edu\/breast-imaging-teach\/wordpress\/wp-content\/uploads\/2025\/06\/US-4-annot-300x190.jpg\" alt=\"\" class=\"wp-image-240\" srcset=\"https:\/\/depts.washington.edu\/breast-imaging-teach\/wordpress\/wp-content\/uploads\/2025\/06\/US-4-annot-300x190.jpg 300w, https:\/\/depts.washington.edu\/breast-imaging-teach\/wordpress\/wp-content\/uploads\/2025\/06\/US-4-annot.jpg 359w\" sizes=\"auto, (max-width: 300px) 100vw, 300px\" \/><\/figure>\n<p>What is this mass?<br \/>A. Cyst<br \/>B. Hamartoma<br \/>C. Lymph Node<\/p>\n<div class=\"wp-block-pb-accordion-item c-accordion__item js-accordion-item no-js\">\n<h3 id=\"at-2288\" class=\"c-accordion__title js-accordion-controller\" role=\"button\">Answer<\/h3>\n<div id=\"ac-2288\" class=\"c-accordion__content\">\n<p><strong>C. Lymph Node<\/strong><\/p>\n<p><strong>Explanation:&nbsp;<\/strong>This is the normal sonographic appearance of an intramammary lymph node, with a thin hypoechoic cortex and a hyperechoic fatty hilum.<\/p>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n","protected":false},"excerpt":{"rendered":"<p>Contributed by: Steven J. Rockoff, MD and Diana L. Lam, MD &#8211; June 1, 2020<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[6],"tags":[],"class_list":["post-228","post","type-post","status-publish","format-standard","hentry","category-quiz"],"_links":{"self":[{"href":"https:\/\/depts.washington.edu\/breast-imaging-teach\/index.php?rest_route=\/wp\/v2\/posts\/228","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/depts.washington.edu\/breast-imaging-teach\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/depts.washington.edu\/breast-imaging-teach\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/depts.washington.edu\/breast-imaging-teach\/index.php?rest_route=\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/depts.washington.edu\/breast-imaging-teach\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=228"}],"version-history":[{"count":3,"href":"https:\/\/depts.washington.edu\/breast-imaging-teach\/index.php?rest_route=\/wp\/v2\/posts\/228\/revisions"}],"predecessor-version":[{"id":726,"href":"https:\/\/depts.washington.edu\/breast-imaging-teach\/index.php?rest_route=\/wp\/v2\/posts\/228\/revisions\/726"}],"wp:attachment":[{"href":"https:\/\/depts.washington.edu\/breast-imaging-teach\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=228"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/depts.washington.edu\/breast-imaging-teach\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=228"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/depts.washington.edu\/breast-imaging-teach\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=228"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}