{"id":79,"date":"2025-05-29T15:35:45","date_gmt":"2025-05-29T15:35:45","guid":{"rendered":"https:\/\/depts.washington.edu\/breast-imaging-teach\/wordpress\/?p=79"},"modified":"2025-06-30T17:20:20","modified_gmt":"2025-06-30T17:20:20","slug":"case-1","status":"publish","type":"post","link":"https:\/\/depts.washington.edu\/breast-imaging-teach\/?p=79","title":{"rendered":"Case 1"},"content":{"rendered":"<p class=\"wp-block-paragraph\">Contributed by: Steven J. Rockoff, MD and Diana L. Lam, MD \u2013 June 1, 2020<\/p>\n<div class=\"wp-block-pb-accordion-item c-accordion__item js-accordion-item no-js\" data-initially-open=\"false\" data-click-to-close=\"true\" data-auto-close=\"true\" data-scroll=\"false\" data-scroll-offset=\"0\">\n<h2 id=\"at-790\" class=\"c-accordion__title js-accordion-controller\" role=\"button\">Question 1<\/h2>\n<div id=\"ac-790\" class=\"c-accordion__content\">\n<p class=\"wp-block-paragraph\">An 82-year-old woman presents for a screening mammogram:<\/p>\n<figure class=\"wp-block-image is-resized\"><img loading=\"lazy\" decoding=\"async\" width=\"296\" height=\"300\" src=\"https:\/\/depts.washington.edu\/breast-imaging-teach\/wordpress\/wp-content\/uploads\/2025\/05\/66-CC-final-296x300.png\" alt=\"\" class=\"wp-image-76\" style=\"width:481px;height:auto\" srcset=\"https:\/\/depts.washington.edu\/breast-imaging-teach\/wordpress\/wp-content\/uploads\/2025\/05\/66-CC-final-296x300.png 296w, https:\/\/depts.washington.edu\/breast-imaging-teach\/wordpress\/wp-content\/uploads\/2025\/05\/66-CC-final-375x381.png 375w, https:\/\/depts.washington.edu\/breast-imaging-teach\/wordpress\/wp-content\/uploads\/2025\/05\/66-CC-final.png 529w\" sizes=\"auto, (max-width: 296px) 100vw, 296px\" \/><\/figure>\n<figure class=\"wp-block-image is-resized\"><img loading=\"lazy\" decoding=\"async\" width=\"300\" height=\"273\" src=\"https:\/\/depts.washington.edu\/breast-imaging-teach\/wordpress\/wp-content\/uploads\/2025\/05\/66-MLO-final-300x273.png\" alt=\"\" class=\"wp-image-77\" style=\"width:481px;height:auto\" srcset=\"https:\/\/depts.washington.edu\/breast-imaging-teach\/wordpress\/wp-content\/uploads\/2025\/05\/66-MLO-final-300x273.png 300w, https:\/\/depts.washington.edu\/breast-imaging-teach\/wordpress\/wp-content\/uploads\/2025\/05\/66-MLO-final-375x341.png 375w, https:\/\/depts.washington.edu\/breast-imaging-teach\/wordpress\/wp-content\/uploads\/2025\/05\/66-MLO-final.png 544w\" sizes=\"auto, (max-width: 300px) 100vw, 300px\" \/><\/figure>\n<p class=\"wp-block-paragraph\">What is the dominant abnormality?<\/p>\n<p class=\"wp-block-paragraph\">A. Mass in the right breast<br \/>B. Mass in the left breast<br \/>C. Focal asymmetry in the right breast<br \/>D. Focal asymmetry in the left breast<br \/>E. No abnormality<\/p>\n<div class=\"wp-block-pb-accordion-item c-accordion__item js-accordion-item no-js\" data-initially-open=\"false\" data-click-to-close=\"true\" data-auto-close=\"true\" data-scroll=\"false\" data-scroll-offset=\"0\">\n<h4 id=\"at-791\" class=\"c-accordion__title js-accordion-controller\" role=\"button\">Answer<\/h4>\n<div id=\"ac-791\" class=\"c-accordion__content\">\n<p class=\"wp-block-paragraph\"><strong>B. Mass in the left breast<\/strong><\/p>\n<figure class=\"wp-block-image is-resized\"><img loading=\"lazy\" decoding=\"async\" width=\"295\" height=\"300\" src=\"https:\/\/depts.washington.edu\/breast-imaging-teach\/wordpress\/wp-content\/uploads\/2025\/05\/66-CC-annot-375x381-1-295x300.png\" alt=\"\" class=\"wp-image-82\" style=\"width:530px;height:auto\" srcset=\"https:\/\/depts.washington.edu\/breast-imaging-teach\/wordpress\/wp-content\/uploads\/2025\/05\/66-CC-annot-375x381-1-295x300.png 295w, https:\/\/depts.washington.edu\/breast-imaging-teach\/wordpress\/wp-content\/uploads\/2025\/05\/66-CC-annot-375x381-1.png 375w\" sizes=\"auto, (max-width: 295px) 100vw, 295px\" \/><\/figure>\n<figure class=\"wp-block-image is-resized\"><img loading=\"lazy\" decoding=\"async\" width=\"300\" height=\"273\" src=\"https:\/\/depts.washington.edu\/breast-imaging-teach\/wordpress\/wp-content\/uploads\/2025\/05\/66-MLO-annot-300x273.png\" alt=\"\" class=\"wp-image-83\" style=\"width:530px;height:auto\" srcset=\"https:\/\/depts.washington.edu\/breast-imaging-teach\/wordpress\/wp-content\/uploads\/2025\/05\/66-MLO-annot-300x273.png 300w, https:\/\/depts.washington.edu\/breast-imaging-teach\/wordpress\/wp-content\/uploads\/2025\/05\/66-MLO-annot-375x341.png 375w, https:\/\/depts.washington.edu\/breast-imaging-teach\/wordpress\/wp-content\/uploads\/2025\/05\/66-MLO-annot.png 544w\" sizes=\"auto, (max-width: 300px) 100vw, 300px\" \/><\/figure>\n<p class=\"wp-block-paragraph\"><strong>Explanation:&nbsp;<\/strong>According to the ACR BI-RADS Atlas, a mass is a three dimensional, space-occupying finding that is seen on two different mammographic projections. It has convex-outward borders and is usually dense in the center compared to its periphery.<\/p>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<div class=\"wp-block-pb-accordion-item c-accordion__item js-accordion-item no-js\" data-initially-open=\"false\" data-click-to-close=\"true\" data-auto-close=\"true\" data-scroll=\"false\" data-scroll-offset=\"0\">\n<h2 id=\"at-792\" class=\"c-accordion__title js-accordion-controller\" role=\"button\">Question 2<\/h2>\n<div id=\"ac-792\" class=\"c-accordion__content\">\n<p class=\"wp-block-paragraph\">What is your assessment and recommendation?<\/p>\n<p class=\"wp-block-paragraph\">A. BI-RADS 4 (Suspicious); Ultrasound-guided biopsy<br \/>B. BI-RADS 4 (Suspicious); Stereotactic biopsy<br \/>C. BI-RADS 0 (Incomplete); Diagnostic MRI<br \/>D. BI-RADS 0 (Incomplete); Diagnostic mammogram and ultrasound<\/p>\n<div class=\"wp-block-pb-accordion-item c-accordion__item js-accordion-item no-js\" data-initially-open=\"false\" data-click-to-close=\"true\" data-auto-close=\"true\" data-scroll=\"false\" data-scroll-offset=\"0\">\n<h4 id=\"at-793\" class=\"c-accordion__title js-accordion-controller\" role=\"button\">Answer<\/h4>\n<div id=\"ac-793\" class=\"c-accordion__content\">\n<p class=\"wp-block-paragraph\"><strong>D. BI-RADS 0 (Incomplete); Diagnostic mammogram and ultrasound<\/strong><\/p>\n<p class=\"wp-block-paragraph\"><strong>Explanation:&nbsp;<\/strong>One must become familiar with the BI-RADS Assessment Categories and their corresponding management recommendations. The next step in the work-up of a screen-detected, potentially suspicious mass is diagnostic mammography and ultrasound. In this situation, BI-RADS Assessment Category 0 (\u201cNeed Additional Imaging Evaluation\u201d) should be assigned and the patient is recalled for dedicated imaging of the finding.<\/p>\n<p class=\"wp-block-paragraph\">Left breast diagnostic mammogram performed with spot compression confirmed the presence of an irregular mass with obscured margins:<\/p>\n<figure class=\"wp-block-image is-resized\"><img loading=\"lazy\" decoding=\"async\" width=\"273\" height=\"300\" src=\"https:\/\/depts.washington.edu\/breast-imaging-teach\/wordpress\/wp-content\/uploads\/2025\/05\/66-LM-diag-273x300.png\" alt=\"\" class=\"wp-image-86\" style=\"width:486px;height:auto\" srcset=\"https:\/\/depts.washington.edu\/breast-imaging-teach\/wordpress\/wp-content\/uploads\/2025\/05\/66-LM-diag-273x300.png 273w, https:\/\/depts.washington.edu\/breast-imaging-teach\/wordpress\/wp-content\/uploads\/2025\/05\/66-LM-diag-375x412.png 375w, https:\/\/depts.washington.edu\/breast-imaging-teach\/wordpress\/wp-content\/uploads\/2025\/05\/66-LM-diag.png 408w\" sizes=\"auto, (max-width: 273px) 100vw, 273px\" \/><\/figure>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<div class=\"wp-block-pb-accordion-item c-accordion__item js-accordion-item no-js\" data-initially-open=\"false\" data-click-to-close=\"true\" data-auto-close=\"true\" data-scroll=\"false\" data-scroll-offset=\"0\">\n<h2 id=\"at-794\" class=\"c-accordion__title js-accordion-controller\" role=\"button\">Question 3<\/h2>\n<div id=\"ac-794\" class=\"c-accordion__content\">\n<p class=\"wp-block-paragraph\">Targeted ultrasound at the 12:00 position revealed:<\/p>\n<figure class=\"wp-block-image\"><img loading=\"lazy\" decoding=\"async\" width=\"300\" height=\"221\" src=\"https:\/\/depts.washington.edu\/breast-imaging-teach\/wordpress\/wp-content\/uploads\/2025\/05\/66-US-300x221.png\" alt=\"\" class=\"wp-image-87\" srcset=\"https:\/\/depts.washington.edu\/breast-imaging-teach\/wordpress\/wp-content\/uploads\/2025\/05\/66-US-300x221.png 300w, https:\/\/depts.washington.edu\/breast-imaging-teach\/wordpress\/wp-content\/uploads\/2025\/05\/66-US-375x277.png 375w, https:\/\/depts.washington.edu\/breast-imaging-teach\/wordpress\/wp-content\/uploads\/2025\/05\/66-US.png 569w\" sizes=\"auto, (max-width: 300px) 100vw, 300px\" \/><\/figure>\n<p class=\"wp-block-paragraph\">What is the best descriptor for the sonographic margins of this hypoechoic mass?<\/p>\n<p class=\"wp-block-paragraph\">A. Circumscribed<br \/>B. Angular<br \/>C. Microlobulated<br \/>D. Indistinct<br \/>E. Spiculated<\/p>\n<div class=\"wp-block-pb-accordion-item c-accordion__item js-accordion-item no-js\" data-initially-open=\"false\" data-click-to-close=\"true\" data-auto-close=\"true\" data-scroll=\"false\" data-scroll-offset=\"0\">\n<h4 id=\"at-795\" class=\"c-accordion__title js-accordion-controller\" role=\"button\">Answer<\/h4>\n<div id=\"ac-795\" class=\"c-accordion__content\">\n<p class=\"wp-block-paragraph\"><strong>C. Microlobulated<\/strong><\/p>\n<p class=\"wp-block-paragraph\"><strong>Explanation:<\/strong>&nbsp;A mass\u2019s margins can appear different between the mammographic and sonographic modalities. When assessing sonographic mass margins, the first step is to determine if this mass is circumscribed (sharply-defined around the entire circumference with an abrupt transition between the mass and surrounding normal tissue) or not circumscribed. \u201cNot circumscribed\u201d is further subdivided into:<\/p>\n<ol class=\"wp-block-list\">\n<li><strong>A<\/strong>ngular<\/li>\n<li><strong>I<\/strong>ndistinct<\/li>\n<li><strong>M<\/strong>icrolobulated<\/li>\n<li><strong>S<\/strong>piculated<\/li>\n<\/ol>\n<p class=\"wp-block-paragraph\">The ultrasound margins of this mass are best described as microlobulated, meaning that the dominant feature is multiple small undulations.<\/p>\n<p class=\"wp-block-paragraph\">A helpful mnemonic to remember the non-circumscribed types of margins is \u201c<strong>AIMS<\/strong>\u201c.<\/p>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<div class=\"wp-block-pb-accordion-item c-accordion__item js-accordion-item no-js\" data-initially-open=\"false\" data-click-to-close=\"true\" data-auto-close=\"true\" data-scroll=\"false\" data-scroll-offset=\"0\">\n<h2 id=\"at-796\" class=\"c-accordion__title js-accordion-controller\" role=\"button\">Question 4<\/h2>\n<div id=\"ac-796\" class=\"c-accordion__content\">\n<p class=\"wp-block-paragraph\">What is your assessment and recommendation?<\/p>\n<p class=\"wp-block-paragraph\">A. BI-RADS 3 (Probably Benign); Recommend six month follow-up<br \/>B. BI-RADS 3 (Probably Benign); Recommend ultrasound-guided biopsy<br \/>C. BI-RADS 4 (Suspicious); Recommend six month follow-up<br \/>D. BI-RADS 4 (Suspicious); Recommend ultrasound-guided biopsy<\/p>\n<div class=\"wp-block-pb-accordion-item c-accordion__item js-accordion-item no-js\" data-initially-open=\"false\" data-click-to-close=\"true\" data-auto-close=\"true\" data-scroll=\"false\" data-scroll-offset=\"0\">\n<h4 id=\"at-797\" class=\"c-accordion__title js-accordion-controller\" role=\"button\">Answer<\/h4>\n<div id=\"ac-797\" class=\"c-accordion__content\">\n<p class=\"wp-block-paragraph\"><strong>D. BI-RADS 4 (Suspicious); Recommend ultrasound-guided biopsy<\/strong><\/p>\n<p class=\"wp-block-paragraph\"><strong>Explanation:<\/strong>&nbsp;Diagnostic mammogram and ultrasound has confirmed the presence of a suspicious mass. BI-RADS Assessment Category 4 (\u201cSuspicious\u201d) is assigned and tissue sampling with biopsy is recommended in order to arrive at the final diagnosis. When technically feasible, ultrasound-guided biopsy is preferred over stereotactic biopsy due to the ability to see the target in real time while acquiring samples.<\/p>\n<figure class=\"wp-block-image is-resized\"><img loading=\"lazy\" decoding=\"async\" width=\"300\" height=\"222\" src=\"https:\/\/depts.washington.edu\/breast-imaging-teach\/wordpress\/wp-content\/uploads\/2025\/05\/66-US-Bx-300x222.png\" alt=\"\" class=\"wp-image-89\" style=\"width:562px;height:auto\" srcset=\"https:\/\/depts.washington.edu\/breast-imaging-teach\/wordpress\/wp-content\/uploads\/2025\/05\/66-US-Bx-300x222.png 300w, https:\/\/depts.washington.edu\/breast-imaging-teach\/wordpress\/wp-content\/uploads\/2025\/05\/66-US-Bx-375x278.png 375w, https:\/\/depts.washington.edu\/breast-imaging-teach\/wordpress\/wp-content\/uploads\/2025\/05\/66-US-Bx.png 571w\" sizes=\"auto, (max-width: 300px) 100vw, 300px\" \/><\/figure>\n<p class=\"wp-block-paragraph\">Ultrasound-guided biopsy revealed invasive ductal carcinoma.<\/p>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<p class=\"wp-block-paragraph\">\n","protected":false},"excerpt":{"rendered":"<p>Contributed by: Steven J. Rockoff, MD and Diana L. Lam, MD \u2013 June 1, 2020<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[6],"tags":[],"class_list":["post-79","post","type-post","status-publish","format-standard","hentry","category-quiz"],"_links":{"self":[{"href":"https:\/\/depts.washington.edu\/breast-imaging-teach\/index.php?rest_route=\/wp\/v2\/posts\/79","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/depts.washington.edu\/breast-imaging-teach\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/depts.washington.edu\/breast-imaging-teach\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/depts.washington.edu\/breast-imaging-teach\/index.php?rest_route=\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/depts.washington.edu\/breast-imaging-teach\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=79"}],"version-history":[{"count":8,"href":"https:\/\/depts.washington.edu\/breast-imaging-teach\/index.php?rest_route=\/wp\/v2\/posts\/79\/revisions"}],"predecessor-version":[{"id":658,"href":"https:\/\/depts.washington.edu\/breast-imaging-teach\/index.php?rest_route=\/wp\/v2\/posts\/79\/revisions\/658"}],"wp:attachment":[{"href":"https:\/\/depts.washington.edu\/breast-imaging-teach\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=79"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/depts.washington.edu\/breast-imaging-teach\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=79"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/depts.washington.edu\/breast-imaging-teach\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=79"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}