{"id":93,"date":"2025-05-29T16:22:44","date_gmt":"2025-05-29T16:22:44","guid":{"rendered":"https:\/\/depts.washington.edu\/breast-imaging-teach\/wordpress\/?p=93"},"modified":"2025-06-30T17:25:47","modified_gmt":"2025-06-30T17:25:47","slug":"case-2","status":"publish","type":"post","link":"https:\/\/depts.washington.edu\/breast-imaging-teach\/?p=93","title":{"rendered":"Case 2"},"content":{"rendered":"<p class=\"wp-block-paragraph\">Contributed by: Steven J. Rockoff, MD and Diana L. Lam, MD &#8211; June 1, 2020<\/p>\n<div class=\"wp-block-pb-accordion-item c-accordion__item js-accordion-item no-js\" data-initially-open=\"false\" data-click-to-close=\"true\" data-auto-close=\"true\" data-scroll=\"false\" data-scroll-offset=\"0\">\n<h2 id=\"at-930\" class=\"c-accordion__title js-accordion-controller\" role=\"button\">Question 1<\/h2>\n<div id=\"ac-930\" class=\"c-accordion__content\">\n<p class=\"wp-block-paragraph\">A 71-year-old woman presents for a screening mammogram:<\/p>\n<figure class=\"wp-block-image is-resized\"><img loading=\"lazy\" decoding=\"async\" width=\"279\" height=\"300\" src=\"https:\/\/depts.washington.edu\/breast-imaging-teach\/wordpress\/wp-content\/uploads\/2025\/05\/2020-3-MLOs-1-279x300.png\" alt=\"\" class=\"wp-image-96\" style=\"width:459px;height:auto\" srcset=\"https:\/\/depts.washington.edu\/breast-imaging-teach\/wordpress\/wp-content\/uploads\/2025\/05\/2020-3-MLOs-1-279x300.png 279w, https:\/\/depts.washington.edu\/breast-imaging-teach\/wordpress\/wp-content\/uploads\/2025\/05\/2020-3-MLOs-1-375x403.png 375w, https:\/\/depts.washington.edu\/breast-imaging-teach\/wordpress\/wp-content\/uploads\/2025\/05\/2020-3-MLOs-1.png 515w\" sizes=\"auto, (max-width: 279px) 100vw, 279px\" \/><\/figure>\n<figure class=\"wp-block-image is-resized\"><img loading=\"lazy\" decoding=\"async\" width=\"300\" height=\"300\" src=\"https:\/\/depts.washington.edu\/breast-imaging-teach\/wordpress\/wp-content\/uploads\/2025\/05\/2020-3-CCs-300x300.png\" alt=\"\" class=\"wp-image-97\" style=\"width:453px;height:auto\" srcset=\"https:\/\/depts.washington.edu\/breast-imaging-teach\/wordpress\/wp-content\/uploads\/2025\/05\/2020-3-CCs-300x300.png 300w, https:\/\/depts.washington.edu\/breast-imaging-teach\/wordpress\/wp-content\/uploads\/2025\/05\/2020-3-CCs-150x150.png 150w, https:\/\/depts.washington.edu\/breast-imaging-teach\/wordpress\/wp-content\/uploads\/2025\/05\/2020-3-CCs-400x400.png 400w, https:\/\/depts.washington.edu\/breast-imaging-teach\/wordpress\/wp-content\/uploads\/2025\/05\/2020-3-CCs-375x374.png 375w, https:\/\/depts.washington.edu\/breast-imaging-teach\/wordpress\/wp-content\/uploads\/2025\/05\/2020-3-CCs.png 526w\" sizes=\"auto, (max-width: 300px) 100vw, 300px\" \/><\/figure>\n<p class=\"wp-block-paragraph\">What is the best interpretation of this exam?<\/p>\n<p class=\"wp-block-paragraph\">A. Mass in the right breast<br \/>B. Mass in the left breast<br \/>C. Focal asymmetry in the right breast<br \/>D. Focal asymmetry in the left breast<\/p>\n<div class=\"wp-block-pb-accordion-item c-accordion__item js-accordion-item no-js\" data-initially-open=\"false\" data-click-to-close=\"true\" data-auto-close=\"true\" data-scroll=\"false\" data-scroll-offset=\"0\">\n<h4 id=\"at-931\" class=\"c-accordion__title js-accordion-controller\" role=\"button\">Answer<\/h4>\n<div id=\"ac-931\" class=\"c-accordion__content\">\n<p class=\"wp-block-paragraph\"><strong>C. Focal asymmetry in the right breast<\/strong><\/p>\n<figure class=\"wp-block-image is-resized\"><img loading=\"lazy\" decoding=\"async\" width=\"279\" height=\"300\" src=\"https:\/\/depts.washington.edu\/breast-imaging-teach\/wordpress\/wp-content\/uploads\/2025\/05\/2020-3-MLO-annot-375x403-1-279x300.png\" alt=\"\" class=\"wp-image-98\" style=\"width:530px;height:auto\" srcset=\"https:\/\/depts.washington.edu\/breast-imaging-teach\/wordpress\/wp-content\/uploads\/2025\/05\/2020-3-MLO-annot-375x403-1-279x300.png 279w, https:\/\/depts.washington.edu\/breast-imaging-teach\/wordpress\/wp-content\/uploads\/2025\/05\/2020-3-MLO-annot-375x403-1.png 375w\" sizes=\"auto, (max-width: 279px) 100vw, 279px\" \/><\/figure>\n<figure class=\"wp-block-image is-resized\"><img loading=\"lazy\" decoding=\"async\" width=\"300\" height=\"300\" src=\"https:\/\/depts.washington.edu\/breast-imaging-teach\/wordpress\/wp-content\/uploads\/2025\/05\/2020-3-CC-annot-375x374-1-300x300.png\" alt=\"\" class=\"wp-image-99\" style=\"width:527px;height:auto\" srcset=\"https:\/\/depts.washington.edu\/breast-imaging-teach\/wordpress\/wp-content\/uploads\/2025\/05\/2020-3-CC-annot-375x374-1-300x300.png 300w, https:\/\/depts.washington.edu\/breast-imaging-teach\/wordpress\/wp-content\/uploads\/2025\/05\/2020-3-CC-annot-375x374-1-150x150.png 150w, https:\/\/depts.washington.edu\/breast-imaging-teach\/wordpress\/wp-content\/uploads\/2025\/05\/2020-3-CC-annot-375x374-1.png 375w\" sizes=\"auto, (max-width: 300px) 100vw, 300px\" \/><\/figure>\n<p class=\"wp-block-paragraph\"><strong>Explanation:&nbsp;<\/strong>According to the ACR BI-RADS Atlas, a focal asymmetry is a unilateral deposit of fibroglandular tissue that does not meet the definition of a mass. It is seen on two projections (CC and MLO), has concave-outward borders, and is usually interspersed with fat. A focal asymmetry that is new or larger since the previous exam (as was the case for this patient) could also be called a \u201cdeveloping asymmetry\u201d.<\/p>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<div class=\"wp-block-pb-accordion-item c-accordion__item js-accordion-item no-js\" data-initially-open=\"false\" data-click-to-close=\"true\" data-auto-close=\"true\" data-scroll=\"false\" data-scroll-offset=\"0\">\n<h2 id=\"at-932\" class=\"c-accordion__title js-accordion-controller\" role=\"button\">Question 2<\/h2>\n<div id=\"ac-932\" class=\"c-accordion__content\">\n<p class=\"wp-block-paragraph\">Now that we\u2019ve identified the right breast developing asymmetry, what is the next step?<\/p>\n<p class=\"wp-block-paragraph\">A. Diagnostic mammogram<br \/>B. Diagnostic ultrasound<br \/>C. Stereotactic biopsy<br \/>D. Follow-up mammogram in six months<\/p>\n<div class=\"wp-block-pb-accordion-item c-accordion__item js-accordion-item no-js\" data-initially-open=\"false\" data-click-to-close=\"true\" data-auto-close=\"true\" data-scroll=\"false\" data-scroll-offset=\"0\">\n<h4 id=\"at-933\" class=\"c-accordion__title js-accordion-controller\" role=\"button\">Answer<\/h4>\n<div id=\"ac-933\" class=\"c-accordion__content\">\n<p class=\"wp-block-paragraph\"><strong>A. Diagnostic mammogram<\/strong><\/p>\n<p class=\"wp-block-paragraph\"><strong>Explanation:&nbsp;<\/strong>The screening exam would be designated BI-RADS 0, Incomplete. A unilateral right diagnostic mammogram is the correct next step in order to determine if this finding is suspicious enough to warrant biopsy.<\/p>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<div class=\"wp-block-pb-accordion-item c-accordion__item js-accordion-item no-js\" data-initially-open=\"false\" data-click-to-close=\"true\" data-auto-close=\"true\" data-scroll=\"false\" data-scroll-offset=\"0\">\n<h2 id=\"at-934\" class=\"c-accordion__title js-accordion-controller\" role=\"button\">Question 3<\/h2>\n<div id=\"ac-934\" class=\"c-accordion__content\">\n<p class=\"wp-block-paragraph\">The right diagnostic mammogram was performed:<\/p>\n<figure class=\"wp-block-image is-resized\"><img loading=\"lazy\" decoding=\"async\" width=\"300\" height=\"169\" src=\"https:\/\/depts.washington.edu\/breast-imaging-teach\/wordpress\/wp-content\/uploads\/2025\/05\/65-Diags-750x422-1-300x169.png\" alt=\"\" class=\"wp-image-102\" style=\"width:760px;height:auto\" srcset=\"https:\/\/depts.washington.edu\/breast-imaging-teach\/wordpress\/wp-content\/uploads\/2025\/05\/65-Diags-750x422-1-300x169.png 300w, https:\/\/depts.washington.edu\/breast-imaging-teach\/wordpress\/wp-content\/uploads\/2025\/05\/65-Diags-750x422-1-375x211.png 375w, https:\/\/depts.washington.edu\/breast-imaging-teach\/wordpress\/wp-content\/uploads\/2025\/05\/65-Diags-750x422-1.png 750w\" sizes=\"auto, (max-width: 300px) 100vw, 300px\" \/><\/figure>\n<p class=\"wp-block-paragraph\">The developing asymmetry persists. A targeted ultrasound at the expected position of the mammographic abnormality in the upper outer quadrant is negative. What your assessment and recommendation?<\/p>\n<p class=\"wp-block-paragraph\">A. BI-RADS 4 (Suspicious); Stereotactic biopsy<br \/>B. BI-RADS 3 (Probably Benign); Follow-up mammogram in six months<br \/>C. BI-RADS 4 (Suspicious); Diagnostic MRI<br \/>D. BI-RADS 4 (Suspicious); Biopsy the approximate area under ultrasound<\/p>\n<div class=\"wp-block-pb-accordion-item c-accordion__item js-accordion-item no-js\" data-initially-open=\"false\" data-click-to-close=\"true\" data-auto-close=\"true\" data-scroll=\"false\" data-scroll-offset=\"0\">\n<h4 id=\"at-935\" class=\"c-accordion__title js-accordion-controller\" role=\"button\">Answer<\/h4>\n<div id=\"ac-935\" class=\"c-accordion__content\">\n<p class=\"wp-block-paragraph\"><strong>A. BI-RADS 4 (Suspicious); Stereotactic biopsy<\/strong><\/p>\n<p class=\"wp-block-paragraph\"><strong>Explanation:&nbsp;<\/strong>A new and persistent suspicious asymmetry, focal asymmetry, or developing asymmetry that has no definite sonographic correlate should be biopsied with stereotactic guidance. In this case, stereotactic biopsy revealed invasive lobular carcinoma.<\/p>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<p class=\"wp-block-paragraph\">\n","protected":false},"excerpt":{"rendered":"<p>Contributed by: Steven J. Rockoff, MD and Diana L. Lam, MD &#8211; June 1, 2020<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[6],"tags":[],"class_list":["post-93","post","type-post","status-publish","format-standard","hentry","category-quiz"],"_links":{"self":[{"href":"https:\/\/depts.washington.edu\/breast-imaging-teach\/index.php?rest_route=\/wp\/v2\/posts\/93","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/depts.washington.edu\/breast-imaging-teach\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/depts.washington.edu\/breast-imaging-teach\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/depts.washington.edu\/breast-imaging-teach\/index.php?rest_route=\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/depts.washington.edu\/breast-imaging-teach\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=93"}],"version-history":[{"count":6,"href":"https:\/\/depts.washington.edu\/breast-imaging-teach\/index.php?rest_route=\/wp\/v2\/posts\/93\/revisions"}],"predecessor-version":[{"id":660,"href":"https:\/\/depts.washington.edu\/breast-imaging-teach\/index.php?rest_route=\/wp\/v2\/posts\/93\/revisions\/660"}],"wp:attachment":[{"href":"https:\/\/depts.washington.edu\/breast-imaging-teach\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=93"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/depts.washington.edu\/breast-imaging-teach\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=93"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/depts.washington.edu\/breast-imaging-teach\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=93"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}