{"id":18,"date":"2017-01-06T22:11:05","date_gmt":"2017-01-06T22:11:05","guid":{"rendered":"http:\/\/depts.washington.edu\/cdbrm\/wordpress\/?page_id=18"},"modified":"2022-08-15T16:22:01","modified_gmt":"2022-08-15T23:22:01","slug":"publications-david-beier","status":"publish","type":"page","link":"https:\/\/depts.washington.edu\/cdbrm\/wordpress\/research-labs-center-for-developmental-biology-and-regenerative-medicine\/beier-lab\/publications-david-beier\/","title":{"rendered":"Publications"},"content":{"rendered":"<p><a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/?term=Beier+DR%5BAuthor%5D\" target=\"_blank\" rel=\"noopener noreferrer\">See all publications&#8230;<\/a><\/p>\n<p>The arginine methyltransferase Carm1 is necessary for heart development. Jamet S, Ha S, Ho TH, Houghtaling S, Timms A, Yu K, Paquette A, Maga AM, Greene NDE, <strong>Beier DR.<\/strong> G3 (Bethesda). 2022 Jul 29;12(8):jkac155.<\/p>\n<hr \/>\n<p>Okamura DM, Brewer CM, Wakenight P, Bahrami N, Bernardi K, Tran A, Olson J, Shi X, Yeh SY, Piliponsky A, Collins SJ, Nguyen ED, Timms AE, MacDonald JW, Bammler TK, Nelson BR, Millen KJ, <strong>Beier DR<\/strong>, Majesky MW. Spiny mice activate unique transcriptional programs after severe kidney injury regenerating organ function without fibrosis. iScience. 2021 Nov 3;24(11):103269.<\/p>\n<hr \/>\n<p>Ha S, Tripathi PP, Daza RA, Hevner RF, <strong>Beier DR<\/strong>. Reelin Mediates Hippocampal Cajal-Retzius Cell Positioning and Infrapyramidal Blade Morphogenesis. J Dev Biol, 2020, Sep 18;8(3):E20.<\/p>\n<hr \/>\n<p>Geister KA, Lopez-Jimenez AJ, Houghtaling S, Ho TH, Vanacore R, <strong>Beier DR.<\/strong> Loss of function of Colgalt1 disrupts collagen post-translational modification and causes musculoskeletal defects. <span style=\"text-decoration: underline;\">Dis Model Mech<\/span>. 2019 Jun 17;12(6)<\/p>\n<hr \/>\n<p>Geister KA, Timms AE, <strong>Beier DR.<\/strong> Optimizing genomic methods for mapping and identification of candidate variants in ENU mutagenesis screens using inbred mice. <span style=\"text-decoration: underline;\">G3 (Bethesda)<\/span>. 2018 Feb 2;8(2):401-409.<\/p>\n<hr \/>\n<p>Strassman A, Schn\u00fctgen F, Dai Q, Jones JC, Gomez AC, Pitstick L, Holton NE, Moskal R, Leslie ER, von Melchner H, <strong>Beier DR<\/strong>, Bjork BC. Generation of a multipurpose <em>Prdm16\u00a0<\/em>mouse allele by targeted gene trapping. <span style=\"text-decoration: underline;\">Dis Model Mech<\/span>. 2017 Jul 1;10(7):909-922.<\/p>\n<hr \/>\n<p class=\"desc\">Cassa CA, Weghorn D, Balick DJ, Jordan DM, Nusinow D, Samocha KE, O&#8217;Donnell-Luria A, MacArthur DG, Daly MJ,\u00a0<b>Beier DR<\/b>, Sunyaev SR. Estimating the selective effects of heterozygous protein-truncating variants from human exome data. <u>Nature Genetics.<\/u> 2017 May;49(5):806-810.<\/p>\n<hr \/>\n<p>Ha S, Tripathi PP, Mihalas AB, Hevner RF, <strong>Beier DR<\/strong>. C-Terminal Region Truncation of RELN Disrupts an Interaction with VLDLR, Causing Abnormal Development of the Cerebral Cortex and Hippocampus. <u>J Neurosci<\/u>. 2017 Jan 25;37(4):960-971.<\/p>\n<hr \/>\n<p>Gallego-Llamas J, Timms AE, Geister KA, Lindsay A, and <strong>Beier DR<\/strong>. Variant mapping and mutation discovery in inbred mice using next-generation sequencing. <u>BMC Genomics. <\/u>2015 Nov 9;16(1):913.<\/p>\n<hr \/>\n<p>Ha S, Stottmann RW, Furley AJ, <strong>Beier DR<\/strong>. A Forward Genetic Screen in Mice Identifies Mutants with Abnormal Cortical Patterning. <u>Cereb Cortex<\/u>. 2015 Jan;25(1):167-79.<\/p>\n<hr \/>\n<p>Tran PV, Talbott GC, Turbe-Doan A, Jacobs DT, Schonfeld MP, Silva LM, Chatterjee A, Prysak M, Allard BA, <strong>Beier DR<\/strong>. Downregulating Hedgehog signaling reduces renal cystogenic potential of mouse models. <u>J. Am Soc Nephrol.,<\/u> 2014 Oct;25(10):2201-12.<\/p>\n<hr \/>\n<p>Manning DK, Sergeev M, van Heesbeen RG, Wong MD, Oh JH, Liu Y, Henkelman RM, Drummond I, Shah JV, <strong>Beier DR<\/strong>.\u00a0 Loss of the ciliary kinase <em>Nek8<\/em> causes left-right asymmetry defects. <u>J Am Soc Nephrol<\/u>. 2013 Jan;24(1):100-12.<\/p>\n<hr \/>\n<p>Leshchiner I, Alexa K, Kelsey P, Adzhubei I, Austin-Tse CA, Cooney JD, Anderson H, King MJ, Stottmann RW, Garnaas MK, Ha S, Drummond IA, Paw BH, North TE, <strong>Beier DR<\/strong>, Goessling W, Sunyaev SR. Mutation mapping and identification by whole-genome sequencing. <u>Genome Res.<\/u> 2012 Aug;22(8):1541-8.<\/p>\n<hr \/>\n<p>Stottmann RW, Turbe-Doan AT, Tran P, Kratz LE, Moran JL<sup>,<\/sup>, Kelley RI, <strong>Beier DR<\/strong>. Cholesterol metabolism is required for intracellular hedgehog signal transduction <em>in vivo<\/em>. <u>PLoS Genetics<\/u>, 2011, 7:e1002224.<\/p>\n<hr \/>\n<p>Stottmann RW, Moran JL, Turbe-Doan A, Driver E, Kelley M, <strong>Beier DR<\/strong>. Focusing forward genetics: A tri-partite ENU screen for neurodevelopmental mutations in the mouse. <u>Genetics<\/u> 2011,188:615-24.<\/p>\n<hr \/>\n<p>Dwyer ND, Manning DK, Moran JL, Mudbhary R, Fleming MS, Favero CB, Vock VM, O&#8217;Leary DD, Walsh CA, <strong>Beier DR<\/strong>. A forward genetic screen with a thalamocortical axon reporter mouse yields novel neurodevelopment mutants and a distinct <em>Emx2<\/em> mutant phenotype. <u>Neural Development<\/u>, 2011 6:3.<\/p>\n<hr \/>\n<p>Smits P, Bolton AD, Funari V, Hong M, Boyden ED, Lu L, Manning DK, Dwyer ND, Moran JL, Prysak M, Merriman B, Nelson SF, Bonafe L, Superti-Furga A, Ikegawa S, Krakow D, Cohn DH, Kirchhausen T, Warman ML, <strong>Beier DR<\/strong>. Lethal skeletal dysplasia in mice and humans lacking the Golgin GMAP-210. <u>N Engl J Med <\/u>2010, 362:206-16.<\/p>\n<hr \/>\n<p>Tran PV, Haycraft CJ, Besschetnova TY, Turbe-Doan A, Stottmann RW, Herron BJ, Chesebro AL,\u00a0 Qiu H, Scherz PJ, Shah JV, Yoder BK, <strong>Beier DR<\/strong>.\u00a0 THM1 negatively modulates mouse Sonic Hedgehog signal transduction and affects retrograde intraflagellar transport in cilia. <u>Nature Genetics<\/u> 2008, 40: 403-10.<\/p>\n<hr \/>\n<p>Moran JL,\u00a0 Bolton AD, Tran PV, Brown A, Dwyer ND, Manning DK, Li C, Montgomery K, Siepka SM, Vitaterna MH, Takahashi JS, Wiltshire T, Kwiatkowski DJ, Kucherlapati R, <strong>Beier DR<\/strong>. Utilization of a whole genome SNP panel for efficient genetic mapping in the mouse. <u>Genome Research <\/u>2006, 16:436-40.<\/p>\n<hr \/>\n<p>Ackerman, K, Herron BJ, Vargas S, Huang H, Kochilas L, Rao C, Pober P, Babiuk R, Epstein J,\u00a0 Greer J, <strong>Beier DR<\/strong>. <em>Fog2<\/em> is required for Normal Diaphragm and Lung Development in Mice and Man. <u>PLoS Genetics <\/u>2005, 1:58-65.<\/p>\n<hr \/>\n<p>Liu S, Lu W, Obara T, Kuida K, Lehoczky J, Dewar K, Drummond IA, <strong>Beier DR<\/strong>. A defect in a novel Nek-family kinase causes cystic kidney disease in the mouse and in zebrafish. <u>Development <\/u>2002, 129:5839-5846.<\/p>\n<hr \/>\n<p>Herron BJ, Lu W, Rao C, Liu S, Peters H, Bronson RT,\u00a0 Justice MJ, McDonald JD, <strong>Beier DR<\/strong>. Efficient generation and mapping of recessive developmental mutations using ENU mutagenesis. <u>Nature Genetics <\/u>2002, 30:185-9.<\/p>\n<hr \/>\n<p><a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/?term=Beier+DR%5BAuthor%5D\" target=\"_blank\" rel=\"noopener noreferrer\">See all publications&#8230;<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>See all publications&#8230; The arginine methyltransferase Carm1 is necessary for heart development. Jamet S, Ha S, Ho TH, Houghtaling S, Timms A, Yu K, Paquette A, Maga AM, Greene NDE, Beier DR. G3 (Bethesda). 2022 Jul 29;12(8):jkac155. Okamura DM, Brewer CM, Wakenight P, Bahrami N, Bernardi K, Tran A, Olson J, Shi X, Yeh SY, &#8230; <\/p>\n<p class=\"read-more-container\"><a title=\"Publications\" class=\"read-more button\" href=\"https:\/\/depts.washington.edu\/cdbrm\/wordpress\/research-labs-center-for-developmental-biology-and-regenerative-medicine\/beier-lab\/publications-david-beier\/#more-18\" aria-label=\"More on Publications\">Read more<\/a><\/p>\n","protected":false},"author":1,"featured_media":587,"parent":10,"menu_order":4,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_monsterinsights_skip_tracking":false,"_monsterinsights_sitenote_active":false,"_monsterinsights_sitenote_note":"","_monsterinsights_sitenote_category":0,"footnotes":""},"class_list":{"0":"post-18","1":"page","2":"type-page","3":"status-publish","4":"has-post-thumbnail","6":"no-featured-image-padding"},"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v18.3 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>Publications - 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