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The UW/FHCRC Center for AIDS Research Developmental Core provides funds to support New Investigator Awards (NIAs) in the area of human immunodeficiency virus (HIV) and acquired immune deficiency syndrome (AIDS) related research.
The purpose of this award program is to encourage junior investigators (at a senior stage of training or recently independent) to conduct independent research, acquire preliminary date to use for exogenous grant submissions, receive mentorship, and write one or more grants to obtain funding to continue their HIV/AIDS research careers.
Note that applicants are required to have an MD or PhD or equivalent terminal degree in order to be eligible to apply. NIH K awards do not impact on eligibility as long as the requested funds support different items. (The research can be on the same topic.) Successful applicants usually have some preliminary data to support their application. Resubmission of revised projects by previous applicants that address critiques of prior proposal is allowed (see application instructions). Applicants are only allowed to submit one application to this program per cycle.
HIV-related research is defined broadly and includes basic science, clinical, epidemiological, behavioral, and health services research.
We specifically encourage applications in the field of HIV Cure, which is one of the CFAR Scientific Working Groups.
Per NIH, we cannot fund research with investigational drugs or clinical trials. If you are considering a study involving approved drugs and/or standard-of-care, please contact Ann Collier (email@example.com, cc: firstname.lastname@example.org; 206-744-3293) to determine whether your proposed project would be eligible for funding through CFAR.
Awards will be up to $45,000/year (direct costs) for non-interdisciplinary applications or up to $55,000 (direct costs) for interdisciplinary projects. Applicants may apply for up to 2 years of funding. The CFAR does not have funds to cover additional indirect costs, but has negotiated indirect cost waivers with several local institutions.
The award can be used for salary, technical support, laboratory supplies, equipment, and travel costs related to the project. Be sure to read our Computer Policy if you would like to budget for a computer [Go here: http://depts.washington.edu/cfar/sites/default/files/uploads/funding/Computer%20Policy.pdf]. Office supplies are not allowed.
Requests for Second Year of Funding: Second year funding is contingent upon demonstration of satisfactory progress during year one. Please include the second year of funding in your application budget, however.
Interdisciplinary Proposals: Multidisciplinary projects are encouraged and are defined as involving 2 or more investigators that have differing areas of expertise or different research focuses, e.g. applicant and a co-investigator with differing areas of expertise or applicant plus 1-2 co-mentors with at least one of the co-mentors having different expertise than the applicant (at least one mentor must be faculty at UW or a UW affiliated institution). The applicant must provide a rationale in the online submission as to why the applicant considers the project to be interdisciplinary.
Mentoring: It is strongly recommended that applicants identify a mentor while preparing their application. If needed, please contact Dr. Collier to provide suggestions for possible mentors. A statement from the applicant’s primary mentor that they have read and discussed the application with the applicant must accompany the application (should be included in the letter of support from the mentor). Please note that a Mentoring Committee will be formed for successful applicants to provide guidance for their career development and to assess progress of each NIA awardee at least annually.
Human Subjects and Animal Care Approvals: Animal Care and Institutional Review Board approvals, if applicable, must be obtained prior to receipt of award funding, but are not required to submit an application.
Use of CFAR Resources: We encourage all applicants to use or contact CFAR Cores or link to CFAR Scientific Working Groups. Several cores and scientific working groups have explicitly offered their consultations services (see Consultation Information below). Information about other CFAR cores and services can be found at http://depts.washington.edu/cfar/find-a-service.
Required for All Applicants
Biostatistical Consultation: All applicants are required to discuss their proposal with one of CFAR’s biostatisticians prior to/during the preparation of their application. This consultation is best done early in the preparation process but must occur before July 13, 2015. Sometimes the detailed discussion requirement is waived for those with prior biostatistical involvement or review of their projects or because a biostatistical consultation is not relevant for the project.
CFAR Membership: All applicants are required to be CFAR Members. Information about membership can be found at http://depts.washington.edu/cfar/get-involved/cfar-membership or by contacting Linh Nguyen (email@example.com).
Letter of Intent: Email Lauren Sterling (firstname.lastname@example.org) a non-binding “email of intent” listing proposed Principal Investigator, Project Title, Mentor(s), and names of collaborators by July 13, 2015. Please also include names and contact information of at least two non-conflicted senior reviewers from outside the Seattle area for your proposal.
Required for Some Applicants
International Applicants: International applicants must obtain approval that they are eligible to apply prior to development of their proposal. They should send an up to date NIH biosketch or curriculum vitae for review to Lauren Sterling (email@example.com; cc: firstname.lastname@example.org; Subject: NIA International Applicant Eligibility Check) no later than July 13, 2015 (preferred by July 6, 2015).
Institutional Approval for non-UW Applicants: Applicants from other institutions should prepare and submit a NIH 398 face page, with concurrence from their institution’s business official. UW applicants do not need departmental, school, or Office of Sponsored Programs signatures. For more information, contact Lauren Sterling (email@example.com; 206-744-8876) prior to the development of their proposal and no later than July 13, 2015.
These consultations are best done early in the preparation process but no later than July 13, 2015.
Administrative Consultation: Applicants from all (including UW) institutions are strongly encouraged to consult with the Program Manager about their budgets to clarify budgetary issues. Please send a draft copy of your budget and justification to Lauren Sterling at firstname.lastname@example.org.
Curative Therapies for HIV Study Consultation: Applicants proposing a study in HIV cure have the opportunity to have an expert from the Curative Therapies for HIV Scientific Working Group consult with them regarding their study. In order to receive this consultation, applicants should contact Tom Andrus at email@example.com.
Substance Abuse and HIV/STI Study Consultation: Applicants proposing a study in the field of substance abuse and HIV/STI have the opportunity to have an expert from the Substance Abuse and HIV/STI Scientific Working Group consult with them regarding their study. In order to receive this consultation, applicants should contact Dennis Donovan at firstname.lastname@example.org.
International Study Consultation: International applicants have the option of receiving an International Core Consultation to help evaluate their study design. In order to receive this consultation, applicants must email a draft of their application to Julia Dettinger at email@example.com.
Health Economics Consultation: Applicants using Health Economic Methods have the options of receiving a Health Economics Impact Study Team Consultation to help their study design. In order to receive this consultation, applicants must email a draft of their application to Julia Dettinger at firstname.lastname@example.org.
Sociobehavioral Study Consultation: Applicants performing behavioral or qualitative research have the opportunity to have an expert from the Sociobehavioral and Prevention Research Core consult with them regarding their study design. In order to receive this consultation, applicants must email a draft of their application to Joanna Bove at email@example.com.
Clinical Research Study Consultation: Those proposing clinical, translational or basic research projects that require access to local research subjects, clinical specimens/procedures or viral assays such as droplet PCR, 2LTR, single copy RNA tests and proviral DNA measurements may contact the Clinical and Retrovirology Research Core to discuss their proposal. Applicants should contact the Core Manager Michalina Montano (firstname.lastname@example.org) with a short description of the study and requested resources for assistance.
Immunological Study Consultation: Applicants proposing an immunology or other appropriate basic research study have the opportunity to have an expert from the Immunology Core consult with them regarding their experimental design. In order to receive this consultation, applicants should contact Stephen De Rosa at email@example.com.
Implementation Science Study Consultation: Applicants proposing a study in the field of implementation science have the opportunity to have an expert from the Implementation Science Working Group consult with them regarding their study. In order to receive this consultation, applicants should contact Kenny Sherr at firstname.lastname@example.org.
Computational Biology and Molecular Profiling Consultation: Applicants proposing a study involving sequence based assays have the opportunity to have an expert from the Molecular Profiling and Computational Biology core consult with them regarding their study. To receive this consultation, applicants should send a brief email to email@example.com including a few sentences describing, briefly, the nature of your questions and your contact information.
Community Action Board Consultation: Applicants proposing to conduct research with human subjects, especially local and/or underserved communities, are encouraged to consult with the CFAR Community Action Board (CAB). Other applicants are welcome to consult with the CAB, also. This consultation can occur at the monthly CAB meeting on June 22nd or on an ad hoc basis. The CAB can advise on the acceptability and feasibility of research methods in underserved communities, as well as discuss implementation and research dissemination strategies (more information: http://depts.washington.edu/cfar/community-action-board-consultations). In order to receive your consultation, please contact Joanna Bove at firstname.lastname@example.org.
Human Subjects and Animal Care Approvals: Prior to funding, a copy of all Institutional Biohazard, Animal Care and IRB approvals must be forwarded to the CFAR Program Manager. If the project involves human subjects and the institutional IRB has deemed the study “greater than minimal risk”, the awardee must submit a Clinical Research Checklist to the CFAR Program Manager before funding is released. Proposals involving either international sites or clinical research above minimal risk will require additional clearance from NIH prior to receipt of an award, which includes IRB approval from all participating sites and human subjects training certification for all key personnel. It is recommended that if your study is minimal risk or below and linked to a non-minimal risk study, you apply for independent approval by the UW IRB – this will expedite the regulatory approval process.
Mentoring Committee and Agreement: Awardees will draw up a brief written agreement with their mentor and identify members of the mentoring committee.
Reporting and Presentation Requirements: Awardees will be required to submit yearly progress reports to the CFAR and make an oral presentation at the annual UW AIDS & STD Research Symposium. The chair of the mentoring committee will also be required to submit a brief progress report annually before Year 2 funding can be received.
CFAR Support: CFAR support (P30 AI027757) must be acknowledged in all publications and presentations derived from CFAR funding (see: http://depts.washington.edu/cfar/discover-cfar/acknowledge-cfar).
Other Support: In the event that pending other support is funded which overlaps with or reduces your effort on this CFAR project, you must notify the CFAR Program Manager. Your funding status will be reviewed and if it is determined that you are unable to meet the specific aims of your CFAR proposal, the CFAR award will be revoked.
Post-Award Requirements: After project is completed, awardees need to agree to provide contact information and respond to annual queries about publications, collaborations and future grants related to the CFAR project.
After completing all pre-submission requirements, submit the following in one PDF (preferred) or MS Word file by 5:00 p.m. PDT July 20, 2015 to https://depts.washington.edu/cfar/find-funding/new-investigator-awards/submission-form. Please note that there are several questions on the submission form that you will need to answer in order to submit your application. They are listed below the proposal information so that you can prepare your answers ahead of time.
The full proposal will be on PHS 398 forms and should follow a modified NIH investigator initiated grant application (R01) format (For more resources see: http://www.niaid.nih.gov/researchfunding/grant/pages/appsamples.aspx) with the modifications listed below). The Research Plan (Specific Aims through Approach) is limited to 4 pages (Bibliography and References Cited sections do not count toward the page limit). No appendices are allowed. Do not submit Targeted/Planned Enrollment Tables. Submit a detailed budget, not a modular budget.
Additional Information Requested in the Online Submission Form:
Topic Key Words (5-10)
Justification for Interdisciplinary Award (if applicable)
Suggested Reviewers (2 non-Seattle, non-conflicted investigators required)
- Previous application title and date submitted
- Major changes from the prior application
- Your response to the reviewer’s comments from your prior submission
- Any other information relevant to the resubmission
The evaluation criteria for proposals include: