{"id":162,"date":"2015-04-08T18:44:13","date_gmt":"2015-04-08T18:44:13","guid":{"rendered":"http:\/\/depts.washington.edu\/cfrtc\/?page_id=162"},"modified":"2015-08-14T19:06:34","modified_gmt":"2015-08-14T19:06:34","slug":"inflammation","status":"publish","type":"page","link":"https:\/\/depts.washington.edu\/cfrtc\/inflammation\/","title":{"rendered":"Host Response"},"content":{"rendered":"<p>[et_pb_section fullwidth=&#8221;on&#8221; specialty=&#8221;off&#8221;][et_pb_fullwidth_slider admin_label=&#8221;Fullwidth Slider&#8221; show_arrows=&#8221;on&#8221; show_pagination=&#8221;on&#8221; auto=&#8221;off&#8221; parallax=&#8221;off&#8221; parallax_method=&#8221;off&#8221; module_id=&#8221;interior&#8221;][et_pb_slide background_image=&#8221;https:\/\/depts.washington.edu\/cfrtc\/wp-content\/uploads\/2014\/12\/microscope.jpg&#8221; background_color=&#8221;#ffffff&#8221; alignment=&#8221;center&#8221; background_layout=&#8221;dark&#8221; \/][\/et_pb_fullwidth_slider][\/et_pb_section][et_pb_section][et_pb_row][et_pb_column type=&#8221;1_4&#8243;][et_pb_sidebar admin_label=&#8221;Host Reponse Core Sidebar&#8221; orientation=&#8221;left&#8221; area=&#8221;et_pb_widget_area_5&#8243; background_layout=&#8221;light&#8221; \/][\/et_pb_column][et_pb_column type=&#8221;3_4&#8243;][et_pb_text admin_label=&#8221;Host Response Core&#8221; background_layout=&#8221;light&#8221; text_orientation=&#8221;left&#8221;]<\/p>\n<h1>Host Response Core Services<\/h1>\n<p>The Host Response Core (HRC) is located within the <a href=\"http:\/\/www.uwhistologyandimaging.org\/\" target=\"_blank\">Histology and Imaging Core<\/a> (HIC) at the South Lake Union (SLU) campus of the University of Washington School of Medicine. The HRC provides access to state-of-the-art imaging facilities and technical assistance for histopathology, immunohistochemistry (IHC), imaging and quantitative morphological analysis to support cystic fibrosis (CF) related research. In addition, the HRC provides training in comparative pathology, immunohistochemistry, imaging and image analysis through seminars and hands on workshops and courses.\u00a0 The HRC will also assist users with gaining access to <a href=\"https:\/\/depts.washington.edu\/flowlab\/\" target=\"_blank\">The Cell Analysis Facility<\/a> in the Department of Immunology at UW-SLU for research requiring flow cytometry.\u00a0 For CFTRC investigators who are submitting a project to the HRC for the first time, please contact the Core Director, <a href=\"mailto:cfrevert@uw.edu\" target=\"_blank\">Dr. Charles Frevert<\/a>, to discuss your research goals and requirements. If you have any questions regarding procedures for submission of your sample or the services provided, please contact <a href=\"mailto:brianj18@uw.edu\" target=\"_blank\">Brian Johnson<\/a>, Manager of the Histology and Imaging Core.<\/p>\n<p>The scientific focus of the HRC is to obtain information on relevant parameters of the host response that is unique to CF using a variety of in vivo and in vitro imaging, analytical and functional endpoints.\u00a0 Among the endpoints and tools the Core\u2019s services will allow include:<\/p>\n<ul>\n<li>Special stains, immunohistochemistry, imaging and image analysis to provide spatial and quantitative data for proteins, cells and bacteria in tissues.<\/li>\n<li>Quantification of chemokines, cytokines, and other factors with ELISA and multiplex assays.<\/li>\n<li>Leukocyte cell counts and differentials in tissue and fluid samples.<\/li>\n<li>Live-cell imaging approaches and morphometric analyses.<\/li>\n<li>Cytometric assays to quantify, isolate, and phenotype specific cell types.<\/li>\n<li>Assays on leukocyte function and activation status.<\/li>\n<\/ul>\n<p>&nbsp;<\/p>\n<p><strong>Supported by a grant from the National Institutes of Health (<a href=\"http:\/\/www.niddk.nih.gov\/Pages\/default.aspx\" target=\"_blank\">NIDDK<\/a> P30 DK 89507). Please reference this grant number on all publications resulting from support provided by this Core Center grant.<\/strong><\/p>\n<p>&nbsp;<\/p>\n<p>[\/et_pb_text][\/et_pb_column][\/et_pb_row][\/et_pb_section]<\/p>\n","protected":false},"excerpt":{"rendered":"<p><div class=\"et_pb_section et_pb_section_0 et_section_regular\" >\n\t\t\t\t\n\t\t\t\t\n\t\t\t\t\n\t\t\t\t\n\t\t\t\t\n\t\t\t\t\n\t\t\t\t\n\t\t\t\t\n\t\t\t\t\n\t\t\t<\/div><div class=\"et_pb_row et_pb_row_0 et_pb_row_empty\">\n\t\t\t\t\n\t\t\t\t\n\t\t\t\t\n\t\t\t\t\n\t\t\t\t\n\t\t\t<\/div> Host Response Core Services The Host Response Core (HRC) is located within the Histology and Imaging Core (HIC) at the South Lake Union (SLU) campus of the University of Washington School of Medicine. The HRC provides access to state-of-the-art imaging facilities and technical assistance for histopathology, immunohistochemistry (IHC), imaging and quantitative morphological analysis to [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"open","ping_status":"open","template":"","meta":{"_et_pb_use_builder":"on","_et_pb_old_content":"","_et_gb_content_width":"","_monsterinsights_skip_tracking":false,"_monsterinsights_sitenote_active":false,"_monsterinsights_sitenote_note":"","_monsterinsights_sitenote_category":0,"footnotes":"","_links_to":"","_links_to_target":""},"_links":{"self":[{"href":"https:\/\/depts.washington.edu\/cfrtc\/wp-json\/wp\/v2\/pages\/162"}],"collection":[{"href":"https:\/\/depts.washington.edu\/cfrtc\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/depts.washington.edu\/cfrtc\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/depts.washington.edu\/cfrtc\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/depts.washington.edu\/cfrtc\/wp-json\/wp\/v2\/comments?post=162"}],"version-history":[{"count":10,"href":"https:\/\/depts.washington.edu\/cfrtc\/wp-json\/wp\/v2\/pages\/162\/revisions"}],"predecessor-version":[{"id":831,"href":"https:\/\/depts.washington.edu\/cfrtc\/wp-json\/wp\/v2\/pages\/162\/revisions\/831"}],"wp:attachment":[{"href":"https:\/\/depts.washington.edu\/cfrtc\/wp-json\/wp\/v2\/media?parent=162"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}