{"id":346,"date":"2015-05-12T23:32:54","date_gmt":"2015-05-12T23:32:54","guid":{"rendered":"http:\/\/depts.washington.edu\/cfrtc\/?page_id=346"},"modified":"2021-12-14T12:04:54","modified_gmt":"2021-12-14T20:04:54","slug":"past-pilots","status":"publish","type":"page","link":"https:\/\/depts.washington.edu\/cfrtc\/past-pilots\/","title":{"rendered":"Past Pilots"},"content":{"rendered":"

[et_pb_section fb_built=”1″ fullwidth=”on” _builder_version=”3.22″ global_colors_info=”{}”][et_pb_fullwidth_slider admin_label=”Fullwidth Slider” module_id=”interior” _builder_version=”3.16″ custom_padding=”|||” custom_padding_tablet=”|||” custom_padding_phone=”|||” box_shadow_style=”preset6″ box_shadow_blur=”10px” box_shadow_color=”rgba(0,0,0,0.1)” show_inner_shadow=”on” global_colors_info=”{}” button_text_size__hover_enabled=”off” button_one_text_size__hover_enabled=”off” button_two_text_size__hover_enabled=”off” button_text_color__hover_enabled=”off” button_one_text_color__hover_enabled=”off” button_two_text_color__hover_enabled=”off” button_border_width__hover_enabled=”off” button_one_border_width__hover_enabled=”off” button_two_border_width__hover_enabled=”off” button_border_color__hover_enabled=”off” button_one_border_color__hover_enabled=”off” button_two_border_color__hover_enabled=”off” button_border_radius__hover_enabled=”off” button_one_border_radius__hover_enabled=”off” button_two_border_radius__hover_enabled=”off” button_letter_spacing__hover_enabled=”off” button_one_letter_spacing__hover_enabled=”off” button_two_letter_spacing__hover_enabled=”off” button_bg_color__hover_enabled=”off” button_one_bg_color__hover_enabled=”off” button_two_bg_color__hover_enabled=”off”][et_pb_slide _builder_version=”3.16″ background_color=”#ffffff” background_image=”https:\/\/depts.washington.edu\/cfrtc\/wp-content\/uploads\/2014\/12\/microscope11.jpg” global_colors_info=”{}” sticky_transition=”on” button_text_size__hover_enabled=”off” button_one_text_size__hover_enabled=”off” button_two_text_size__hover_enabled=”off” button_text_color__hover_enabled=”off” button_one_text_color__hover_enabled=”off” button_two_text_color__hover_enabled=”off” button_border_width__hover_enabled=”off” button_one_border_width__hover_enabled=”off” button_two_border_width__hover_enabled=”off” button_border_color__hover_enabled=”off” button_one_border_color__hover_enabled=”off” button_two_border_color__hover_enabled=”off” button_border_radius__hover_enabled=”off” button_one_border_radius__hover_enabled=”off” button_two_border_radius__hover_enabled=”off” button_letter_spacing__hover_enabled=”off” button_one_letter_spacing__hover_enabled=”off” button_two_letter_spacing__hover_enabled=”off” button_bg_color__hover_enabled=”off” button_one_bg_color__hover_enabled=”off” button_two_bg_color__hover_enabled=”off”][\/et_pb_slide][\/et_pb_fullwidth_slider][\/et_pb_section][et_pb_section fb_built=”1″ _builder_version=”3.22″ global_colors_info=”{}”][et_pb_row _builder_version=”3.25″ background_size=”initial” background_position=”top_left” background_repeat=”repeat” global_colors_info=”{}” column_structure=”1_4,3_4″][et_pb_column type=”1_4″ _builder_version=”3.25″ custom_padding=”|||” global_colors_info=”{}” custom_padding__hover=”|||”][et_pb_sidebar area=”et_pb_widget_area_10″ admin_label=”Pilots Sidebar” _builder_version=”4.14.2″ hover_enabled=”0″ global_colors_info=”{}” sticky_enabled=”0″][\/et_pb_sidebar][\/et_pb_column][et_pb_column type=”3_4″ _builder_version=”3.25″ custom_padding=”|||” global_colors_info=”{}” custom_padding__hover=”|||”][et_pb_text admin_label=”Text” _builder_version=”3.27.4″ background_size=”initial” background_position=”top_left” background_repeat=”repeat” global_colors_info=”{}”]<\/p>\n

Past Pilots<\/h1>\n\n\n\n\n\t\n\n\t\n\t\n\t\n\t\n\t\n\t\n\t\n\t\n\t\n\t\n\t\n\t\n\t\n\t\n\t\n\t\n\t\n\t\n\t\n\t\n\t\n\t\n\t\n\t\n\t\n\t\n\t\n\t\n\t\n\t\n\t\n\t\n\t
Funding Source<\/th>Principal Investigator
\nDepartment<\/th>		Funding Period<\/th>Project title<\/th>\n<\/tr>\n<\/thead>\n
P30 CFRTC<\/td>Beno Freedman PhD<\/a> Nephrology<\/td>2022-24<\/td>Modeling CFTR function with human kidney organoids<\/td>\n<\/tr>\n
CFF RDP<\/td>Eric Morrell, MD<\/a>
\nPulmonary<\/td>		2021-24<\/td>Role of Soluble PD-L1 in Chronic Lung Allograft Dysfunction<\/td>\n<\/tr>\n
CFF RDP<\/td>Amy Willis, PhD<\/a>
\nBiostatistics<\/td>		2021-23<\/td>Estimating the composition of the cystic fibrosis pulmonary microbiome
\n<\/td>\n<\/tr>\n
P30 CFRTC<\/td>Pavan Bhatraju, MD<\/a>
\nPulmonary
\n<\/td>		2018-23<\/td>Identification of Predictive Biomarkers for Antibiotic Associated Nephrotoxicity in Cystic Fibrosis<\/a><\/td>\n<\/tr>\n
P30 CFRTC<\/td>Jim Kublin, MD, MPH<\/a>
\nVaccine & ID, Hutch
\n<\/td>		2020-23<\/td>Investigating Mechanisms of Vaccine Response Deficiency in Cystic Fibrosis<\/a><\/td>\n<\/tr>\n
P30 CFRTC<\/td>Sakeneh Zraika, PhD<\/a>
\nMetabolism<\/td>		2020-23<\/td>Impact of Intra-Islet GLP-1 Signaling on \u00df-cell Function in CFRD<\/a><\/td>\n<\/tr>\n
CFF RDP<\/td>Eric Morrell, MD, MA<\/a>
\nPulmonary<\/td>		2019-22<\/td>Immune Tolerance and Inflammation in Lung Transplant Rejection<\/a><\/td>\n<\/tr>\n
CFF RDP<\/td>David Sherman, PhD<\/a>
\nMicrobiology<\/td>		2019-21<\/td>Inferring drug interactions in M. abscessus using chemo-genomics and orthology<\/a><\/td>\n<\/tr>\n
CFF RDP<\/td>Richard James, PhD<\/a>
\nJason Debley, MD<\/a>
\nPediatrics<\/td>		2019-20<\/td>Approach to CFTR Editing in Differentiated Airway Epithelial Cells<\/a><\/td>\n<\/tr>\n
P30 CFRTC<\/td> Marion Pepper, PhD <\/a>
Immunology<\/td>		2018-21<\/td>Pseudomonas-specific immune responses in CF patients<\/a><\/td>\n<\/tr>\n
P30 CFRTC<\/td>Jisun Paik, PhD<\/a>
Comparative Medicine
\n Luke Hoffman, MD, PhD<\/a>, Pediatrics<\/td>		2018-20<\/td>Gastrointestinal dysbiosis as a modifier of CF infant somatic growth: A murine investigation<\/a><\/td>\n<\/tr>\n
P30 CFRTC<\/td> Steve Salipante, MD, PhD<\/a>, Lab Medicine<\/td>2018-20<\/td>Cell-free Bacterial DNA to Identify Mycobacterial Lung Pathogens in CF<\/a><\/td>\n<\/tr>\n
CFF RDP<\/td>Andrew Graustein, MD<\/a>
\nPulmonary<\/td>		2017-20<\/td>The NLRP3 Inflammasome in The Cystic Fibrosis Lung<\/a><\/td>\n<\/tr>\n
CFF RDP<\/td>Thomas Hawn, MD, PhD<\/a>
\nAllergy & ID<\/td>		2017-19<\/td>The Inflammasome in Cystic Fibrosis<\/a><\/td>\n<\/tr>\n
CFF RDP<\/td>Jason Debley, MD<\/a>
\nDavid Nichols, MD
\nPediatrics<\/td>		2017-19<\/td>Testing association between epithelial chloride transport and measures of clinical improvement<\/a><\/td>\n<\/tr>\n
P30 CFRTC<\/td>Matthew Parsek, PhD<\/a>
\nMicrobiology<\/td>		2016-20<\/td>Microbial colonization and adaptation to the CF gut<\/td>\n<\/tr>\n
P30 CFRTC<\/td>Neal Paragas, PhD<\/a>
\nNephrology<\/td>		2016-19<\/td>Identification of Biomarkers for Cystic Fibrosis Associated Nephrotoxicity<\/td>\n<\/tr>\n
P30 CFRTC<\/td>Lynn Hajjar, DVM, PhD<\/a>
\nComparative Medicine
\n<\/td>		2016-18<\/td>Lung and gastrointestinal homeostasis in a germ-free CF mouse model<\/a><\/td>\n<\/tr>\n
P30 CFRTC<\/td>Marika Bogdani, PhD<\/a>
\nBenaroya<\/td>		2016-17<\/td>Hyalouronan and hlyaladherins in the pathogenesis of cystic fibrosis related diabetes<\/td>\n<\/tr>\n
CFF RDP<\/td>Steve Salipante, MD, PhD<\/a>, Lab Medicine<\/td>2015-18<\/td>Mechanisms and fitness of spontaneous aztreonam resistance in Pseudomonas aeruginosa<\/em><\/a><\/td>\n<\/tr>\n
CFF RDP<\/td>William Altemeier, MD<\/a>
\nPulmonary<\/td>		2015-18<\/td>Role of the Microvasculature in Neutrophilic Lung Disease of Cystic Fibrosis<\/a><\/td>\n<\/tr>\n
P30 CFRTC<\/td>Steven Kahn, MB, ChB<\/a>
\nMetabolism<\/td>		2014-19<\/td>Mechanisms of Late Hypoglycemia in Cystic Fibrosis<\/a><\/td>\n<\/tr>\n
P30 CFRTC<\/td>Ian de Boer, MD<\/a>
\nNephrology<\/td>		2014-18<\/td>Vitamin D metabolism in cystic fibrosis<\/a><\/td>\n<\/tr>\n
CFF RDP<\/td>Rafael Hernandez, MD, PhD<\/a>, Pediatrics<\/td>2014-17<\/td>Efflux Pumps in Nontuberculosis Mycobacteria<\/a><\/td>\n<\/tr>\n
P30 CFRTC<\/td>Anne Manicone, MD<\/a>
\nPulmonary<\/td>		2014-17<\/td>Functional Consequences and Signaling Pathways of Macrophage Repolarization<\/a><\/td>\n<\/tr>\n
CFF RDP<\/td>Donald Chi, DDS, PhD<\/a>
\nDentistry<\/td>		2013-17<\/td>Testing a Multifactorial Caries Model for Pediatric Patients with Cystic Fibrosis<\/a><\/td>\n<\/tr>\n
P30 CFRTC<\/td>Elhanan Borenstein, PhD<\/a>, Genome Sciences<\/td>2013-14<\/td>Advanced computational methods for identifying compositional shifts in the CF gut microbiome<\/a><\/td>\n<\/tr>\n
P30 CFRTC<\/td>Lucas Hoffman, MD, PhD<\/a>
\nPediatrics<\/td>		2013-14<\/td>Acute Effects of Kalydeco in People with CF and the G551D Mutation<\/a><\/td>\n<\/tr>\n
P30 CFRTC<\/td>Rebecca Hull, PhD<\/a>
\nMetabolism
\nSrinath Sanda, MD<\/a>
\nPediatrics, UCSF<\/td>		2012-17<\/td>Role of Islet Amyloid and IL-1\u03b2 Signaling in \u03b2-cell Loss in Cystic Fibrosis-Related Diabetes<\/a><\/td>\n<\/tr>\n
P30 CFRTC<\/td>Ian Sweet, PhD<\/a>
\nMetabolism<\/td>		2012-15<\/td>Biochemical Mechanisms Mediating Impaired Insulin Secretion in Mouse Models of Cystic Fibrosis<\/a><\/td>\n<\/tr>\n
P30 CFRTC<\/td>Lev Becker, PhD<\/a>
\nPediatrics, U Chicago<\/td>		2012-15<\/td>Investigating the effects of CFTR Correction on Myeloid Cell Function<\/a><\/td>\n<\/tr>\n
P30 CFRTC<\/td>Lev Becker, PhD<\/a>
\nPulmonary<\/td>		2010-13<\/td>Macrophage and Dendritic Cell Pathways in Cystic Fibrosis<\/a><\/td>\n<\/tr>\n
P30 CFRTC<\/td>Lucas Hoffman, MD, PhD<\/a>
\nPediatrics<\/td>		2010-13<\/td>Describing the gut microbiome of early childhood and infant Cystic Fibrosis patients<\/a><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n\n

 <\/p>\n

 
\n[\/et_pb_text][\/et_pb_column][\/et_pb_row][\/et_pb_section]<\/p>\n","protected":false},"excerpt":{"rendered":"

Past Pilots \n\n\n\n\t\n\n\t\n\t\n\t\n\t\n\t\n\t\n\t\n\t\n\t\n\t\n\t\n\t\n\t\n\t\n\t\n\t\n\t\n\t\n\t\n\t\n\t\n\t\n\t\n\t\n\t\n\t\n\t\n\t\n\t\n\t\n\t\n\t\n\t
Funding Source<\/th>Principal Investigator
\nDepartment<\/th>		Funding Period<\/th>Project title<\/th>\n<\/tr>\n<\/thead>\n
P30 CFRTC<\/td>Beno Freedman PhD<\/a> Nephrology<\/td>2022-24<\/td>Modeling CFTR function with human kidney organoids<\/td>\n<\/tr>\n
CFF RDP<\/td>Eric Morrell, MD<\/a>
\nPulmonary<\/td>		2021-24<\/td>Role of Soluble PD-L1 in Chronic Lung Allograft Dysfunction<\/td>\n<\/tr>\n
CFF RDP<\/td>Amy Willis, PhD<\/a>
\nBiostatistics<\/td>		2021-23<\/td>Estimating the composition of the cystic fibrosis pulmonary microbiome
\n<\/td>\n<\/tr>\n
P30 CFRTC<\/td>Pavan Bhatraju, MD<\/a>
\nPulmonary
\n<\/td>		2018-23<\/td>Identification of Predictive Biomarkers for Antibiotic Associated Nephrotoxicity in Cystic Fibrosis<\/a><\/td>\n<\/tr>\n
P30 CFRTC<\/td>Jim Kublin, MD, MPH<\/a>
\nVaccine & ID, Hutch
\n<\/td>		2020-23<\/td>Investigating Mechanisms of Vaccine Response Deficiency in Cystic Fibrosis<\/a><\/td>\n<\/tr>\n
P30 CFRTC<\/td>Sakeneh Zraika, PhD<\/a>
\nMetabolism<\/td>		2020-23<\/td>Impact of Intra-Islet GLP-1 Signaling on \u00df-cell Function in CFRD<\/a><\/td>\n<\/tr>\n
CFF RDP<\/td>Eric Morrell, MD, MA<\/a>
\nPulmonary<\/td>		2019-22<\/td>Immune Tolerance and Inflammation in Lung Transplant Rejection<\/a><\/td>\n<\/tr>\n
CFF RDP<\/td>David Sherman, PhD<\/a>
\nMicrobiology<\/td>		2019-21<\/td>Inferring drug interactions in M. abscessus using chemo-genomics and orthology<\/a><\/td>\n<\/tr>\n
CFF RDP<\/td>Richard James, PhD<\/a>
\nJason Debley, MD<\/a>
\nPediatrics<\/td>		2019-20<\/td>Approach to CFTR Editing in Differentiated Airway Epithelial Cells<\/a><\/td>\n<\/tr>\n
P30 CFRTC<\/td> Marion Pepper, PhD <\/a>
Immunology<\/td>		2018-21<\/td>Pseudomonas-specific immune responses in CF patients<\/a><\/td>\n<\/tr>\n
P30 CFRTC<\/td>Jisun Paik, PhD<\/a>
Comparative Medicine
\n Luke Hoffman, MD, PhD<\/a>, Pediatrics<\/td>		2018-20<\/td>Gastrointestinal dysbiosis as a modifier of CF infant somatic growth: A murine investigation<\/a><\/td>\n<\/tr>\n
P30 CFRTC<\/td> Steve Salipante, MD, PhD<\/a>, Lab Medicine<\/td>2018-20<\/td>Cell-free Bacterial DNA to Identify Mycobacterial Lung Pathogens in CF<\/a><\/td>\n<\/tr>\n
CFF RDP<\/td>Andrew Graustein, MD<\/a>
\nPulmonary<\/td>		2017-20<\/td>The NLRP3 Inflammasome in The Cystic Fibrosis Lung<\/a><\/td>\n<\/tr>\n
CFF RDP<\/td>Thomas Hawn, MD, PhD<\/a>
\nAllergy & ID<\/td>		2017-19<\/td>The Inflammasome in Cystic Fibrosis<\/a><\/td>\n<\/tr>\n
CFF RDP<\/td>Jason Debley, MD<\/a>
\nDavid Nichols, MD
\nPediatrics<\/td>		2017-19<\/td>Testing association between epithelial chloride transport and measures of clinical improvement<\/a><\/td>\n<\/tr>\n
P30 CFRTC<\/td>Matthew Parsek, PhD<\/a>
\nMicrobiology<\/td>		2016-20<\/td>Microbial colonization and adaptation to the CF gut<\/td>\n<\/tr>\n
P30 CFRTC<\/td>Neal Paragas, PhD<\/a>
\nNephrology<\/td>		2016-19<\/td>Identification of Biomarkers for Cystic Fibrosis Associated Nephrotoxicity<\/td>\n<\/tr>\n
P30 CFRTC<\/td>Lynn Hajjar, DVM, PhD<\/a>
\nComparative Medicine
\n<\/td>		2016-18<\/td>Lung and gastrointestinal homeostasis in a germ-free CF mouse model<\/a><\/td>\n<\/tr>\n
P30 CFRTC<\/td>Marika Bogdani, PhD<\/a>
\nBenaroya<\/td>		2016-17<\/td>Hyalouronan and hlyaladherins in the pathogenesis of cystic fibrosis related diabetes<\/td>\n<\/tr>\n
CFF RDP<\/td>Steve Salipante, MD, PhD<\/a>, Lab Medicine<\/td>2015-18<\/td>Mechanisms and fitness of spontaneous aztreonam resistance in Pseudomonas aeruginosa<\/em><\/a><\/td>\n<\/tr>\n
CFF RDP<\/td>William Altemeier, MD<\/a>
\nPulmonary<\/td>		2015-18<\/td>Role of the Microvasculature in Neutrophilic Lung Disease of Cystic Fibrosis<\/a><\/td>\n<\/tr>\n
P30 CFRTC<\/td>Steven Kahn, MB, ChB<\/a>
\nMetabolism<\/td>		2014-19<\/td>Mechanisms of Late Hypoglycemia in Cystic Fibrosis<\/a><\/td>\n<\/tr>\n
P30 CFRTC<\/td>Ian de Boer, MD<\/a>
\nNephrology<\/td>		2014-18<\/td>Vitamin D metabolism in cystic fibrosis<\/a><\/td>\n<\/tr>\n
CFF RDP<\/td>Rafael Hernandez, MD, PhD<\/a>, Pediatrics<\/td>2014-17<\/td>Efflux Pumps in Nontuberculosis Mycobacteria<\/a><\/td>\n<\/tr>\n
P30 CFRTC<\/td>Anne Manicone, MD<\/a>
\nPulmonary<\/td>		2014-17<\/td>Functional Consequences and Signaling Pathways of Macrophage Repolarization<\/a><\/td>\n<\/tr>\n
CFF RDP<\/td>Donald Chi, DDS, PhD<\/a>
\nDentistry<\/td>		2013-17<\/td>Testing a Multifactorial Caries Model for Pediatric Patients with Cystic Fibrosis<\/a><\/td>\n<\/tr>\n
P30 CFRTC<\/td>Elhanan Borenstein, PhD<\/a>, Genome Sciences<\/td>2013-14<\/td>Advanced computational methods for identifying compositional shifts in the CF gut microbiome<\/a><\/td>\n<\/tr>\n
P30 CFRTC<\/td>Lucas Hoffman, MD, PhD<\/a>
\nPediatrics<\/td>		2013-14<\/td>Acute Effects of Kalydeco in People with CF and the G551D Mutation<\/a><\/td>\n<\/tr>\n
P30 CFRTC<\/td>Rebecca Hull, PhD<\/a>
\nMetabolism
\nSrinath Sanda, MD<\/a>
\nPediatrics, UCSF<\/td>		2012-17<\/td>Role of Islet Amyloid and IL-1\u03b2 Signaling in \u03b2-cell Loss in Cystic Fibrosis-Related Diabetes<\/a><\/td>\n<\/tr>\n
P30 CFRTC<\/td>Ian Sweet, PhD<\/a>
\nMetabolism<\/td>		2012-15<\/td>Biochemical Mechanisms Mediating Impaired Insulin Secretion in Mouse Models of Cystic Fibrosis<\/a><\/td>\n<\/tr>\n
P30 CFRTC<\/td>Lev Becker, PhD<\/a>
\nPediatrics, U Chicago<\/td>		2012-15<\/td>Investigating the effects of CFTR Correction on Myeloid Cell Function<\/a><\/td>\n<\/tr>\n
P30 CFRTC<\/td>Lev Becker, PhD<\/a>
\nPulmonary<\/td>		2010-13<\/td>Macrophage and Dendritic Cell Pathways in Cystic Fibrosis<\/a><\/td>\n<\/tr>\n
P30 CFRTC<\/td>Lucas Hoffman, MD, PhD<\/a>
\nPediatrics<\/td>		2010-13<\/td>Describing the gut microbiome of early childhood and infant Cystic Fibrosis patients<\/a><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n    <\/p>\n","protected":false},"author":1,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"open","template":"","meta":{"_et_pb_use_builder":"on","_et_pb_old_content":"","_et_gb_content_width":"","_monsterinsights_skip_tracking":false,"_monsterinsights_sitenote_active":false,"_monsterinsights_sitenote_note":"","_monsterinsights_sitenote_category":0,"footnotes":"","_links_to":"","_links_to_target":""},"_links":{"self":[{"href":"https:\/\/depts.washington.edu\/cfrtc\/wp-json\/wp\/v2\/pages\/346"}],"collection":[{"href":"https:\/\/depts.washington.edu\/cfrtc\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/depts.washington.edu\/cfrtc\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/depts.washington.edu\/cfrtc\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/depts.washington.edu\/cfrtc\/wp-json\/wp\/v2\/comments?post=346"}],"version-history":[{"count":11,"href":"https:\/\/depts.washington.edu\/cfrtc\/wp-json\/wp\/v2\/pages\/346\/revisions"}],"predecessor-version":[{"id":2493,"href":"https:\/\/depts.washington.edu\/cfrtc\/wp-json\/wp\/v2\/pages\/346\/revisions\/2493"}],"wp:attachment":[{"href":"https:\/\/depts.washington.edu\/cfrtc\/wp-json\/wp\/v2\/media?parent=346"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}