ResultsSharingFormat: Difference between revisions
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The following variables should be included when sharing imputed results for meta-analysis | The following variables should be included when sharing imputed results for meta-analysis; large files can be shared among small groups via secure file transfer site (as described in [[ResultsSharing|Results Sharing]]) | ||
{| class="prettytable" width="800" border="1" | {| class="prettytable" width="800" border="1" | ||
|- | |- | ||
| variable name | | width="200" | '''''variable name''''' | ||
| description | | '''''description''''''''''''''' | ||
|- | |- | ||
| SNPID | | '''SNPID''' | ||
| SNP ID as rs number | | SNP ID as rs number | ||
|- | |- | ||
| chr | | '''chr''' | ||
| chromosome number | | chromosome number | ||
|- | |- | ||
| position | | '''position''' | ||
| physical position for the reference sequence (NCBI 35, 36) | | physical position for the reference sequence (NCBI 35, 36) | ||
|- | |- | ||
| coded_all | | '''coded_all''' | ||
| coded allele, also called modeled allele (in example of A/G SNP in which AA=0, AG=1 and GG=2, the coded allele is G) | | coded allele, also called modeled allele (in example of A/G SNP in which AA=0, AG=1 and GG=2, the coded allele is G) | ||
|- | |- | ||
| noncoded_all | | '''noncoded_all''' | ||
| the alternate allele | | the alternate allele | ||
|- | |- | ||
| strand_genome | | '''strand_genome''' | ||
| + or -, representing either the positive/forward strand or the negative/reverse strand of the human genome reference sequence; to clarify which strand the coded_all and noncoded_all are on | | + or -, representing either the positive/forward strand or the negative/reverse strand of the human genome reference sequence; to clarify which strand the coded_all and noncoded_all are on | ||
|- | |- | ||
| beta | | '''beta''' | ||
| beta estimate from genotype-phenotype association, at least 5 decimal places | | beta estimate from genotype-phenotype association, at least 5 decimal places | ||
|- | |- | ||
| SE | | '''SE''' | ||
| standard error of beta estimate, to at least 5 decimal places | | standard error of beta estimate, to at least 5 decimal places | ||
|- | |- | ||
| pval | | '''pval''' | ||
| p-value of test statistic, here just as a double check | | p-value of test statistic, here just as a double check | ||
|- | |- | ||
| AF_coded_all | | '''AF_coded_all''' | ||
| allele frequency for the coded allele | | allele frequency for the coded allele | ||
|- | |- | ||
| HWE_pval | | '''HWE_pval''' | ||
| exact test Hardy-Weinberg equilibrium p-value | | exact test Hardy-Weinberg equilibrium p-value | ||
|- | |- | ||
| callrate | | '''callrate''' | ||
| genotyping callrate after exclusions | | genotyping callrate after exclusions | ||
|- | |- | ||
| n_total | | '''n_total''' | ||
| total sample with phenotype and genotype for SNP | | total sample with phenotype and genotype for SNP | ||
|- | |- | ||
| imputed | | '''imputed''' | ||
| 1/0 coding; 1=imputed SNP, 0=not imputed | | 1/0 coding; 1=imputed SNP, 0=not imputed | ||
|- | |- | ||
| used_for_imp | | '''used_for_imp''' | ||
| 1/0 coding; 1=used for imputation, 0=not used for imputation | | 1/0 coding; 1=used for imputation, 0=not used for imputation | ||
|- | |- | ||
| oevar_imp | | '''oevar_imp''' | ||
| observed divided by expected variance for imputed allele dosage | | observed divided by expected variance for imputed allele dosage | ||
|- | |- | ||
| avpostprob | | '''avpostprob''' | ||
| average posterior probability for imputed SNP allele dosage* (applies to best-guess genotype imputation) | | average posterior probability for imputed SNP allele dosage* ''(applies to best-guess genotype imputation)'' | ||
|} | |} | ||
''Please note that a README should be uploaded with a very brief description of the data uploaded, the date, the NCBI human genome reference sequence used (e.g. NCBI 36.2) for strand reference, and the scale of the beta estimates | ''Please note that a README should be uploaded with a very brief description of the data uploaded, the date, the NCBI human genome reference sequence used (e.g. NCBI 36.2) for strand reference, and the scale of the beta estimates; please also include in the README the SNP HWE p-value, callrate and minor allele frequency filters that have been applied.'' |
Revision as of 17:50, 9 May 2008
The following variables should be included when sharing imputed results for meta-analysis; large files can be shared among small groups via secure file transfer site (as described in Results Sharing)
variable name | description'''''''''' |
SNPID | SNP ID as rs number |
chr | chromosome number |
position | physical position for the reference sequence (NCBI 35, 36) |
coded_all | coded allele, also called modeled allele (in example of A/G SNP in which AA=0, AG=1 and GG=2, the coded allele is G) |
noncoded_all | the alternate allele |
strand_genome | + or -, representing either the positive/forward strand or the negative/reverse strand of the human genome reference sequence; to clarify which strand the coded_all and noncoded_all are on |
beta | beta estimate from genotype-phenotype association, at least 5 decimal places |
SE | standard error of beta estimate, to at least 5 decimal places |
pval | p-value of test statistic, here just as a double check |
AF_coded_all | allele frequency for the coded allele |
HWE_pval | exact test Hardy-Weinberg equilibrium p-value |
callrate | genotyping callrate after exclusions |
n_total | total sample with phenotype and genotype for SNP |
imputed | 1/0 coding; 1=imputed SNP, 0=not imputed |
used_for_imp | 1/0 coding; 1=used for imputation, 0=not used for imputation |
oevar_imp | observed divided by expected variance for imputed allele dosage |
avpostprob | average posterior probability for imputed SNP allele dosage* (applies to best-guess genotype imputation) |
Please note that a README should be uploaded with a very brief description of the data uploaded, the date, the NCBI human genome reference sequence used (e.g. NCBI 36.2) for strand reference, and the scale of the beta estimates; please also include in the README the SNP HWE p-value, callrate and minor allele frequency filters that have been applied.