ResultsSharingFormat

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The following variables should be included when sharing imputed results for meta-analysis:

variable name description
SNPID SNP ID as rs number
chr chromosome number
position physical position for the reference sequence (NCBI 35, 36)
coded_all coded allele, also called modeled allele (in example of A/G SNP in which AA=0, AG=1 and GG=2, the coded allele is G)
noncoded_all the alternate allele
strand_genome + or -, representing either the positive/forward strand or the negative/reverse strand of the human genome reference sequence; to clarify which strand the coded_all and noncoded_all are on
beta beta estimate from genotype-phenotype association, at least 5 decimal places
SE standard error of beta estimate, to at least 5 decimal places
pval p-value of test statistic, here just as a double check
AF_coded_all allele frequency for the coded allele
HWE_pval exact test Hardy-Weinberg equilibrium p-value
callrate genotyping callrate after exclusions
n_total total sample with phenotype and genotype for SNP
imputed 1/0 coding; 1=imputed SNP, 0=not imputed
used_for_imp 1/0 coding; 1=used for imputation, 0=not used for imputation
oevar_imp observed divided by expected variance for imputed allele dosage
avpostprob average posterior probability for imputed SNP allele dosage* (applies to best-guess genotype imputation)

Please note that a README should be uploaded with a very brief description of the data uploaded, the date, the NCBI human genome reference sequence used (e.g. NCBI 36.2) for strand reference, and the scale of the beta estimates; ; please also include in the README the SNP HWE p-value, callrate and minor allele frequency filters that have been applied.