CHDD

Center on Human Development and Disability

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Nicholas Poolos, M.D., Ph.D.

Professor of Neurology
Research Affiliate, Center on Human Development and Disability
npoolos@uw.edu
206-341-5423
University of Washington
Box 356560
Seattle, WA 98195-6560

Dr. Poolos studies epilepsy, one of the most common causes of neurological disability in children. Current treatments do not reliably prevent seizures and associated neuronal damage in about 25 percent of individuals with epilepsy. In particular, Poolos and his colleagues study links between epilepsy and neuronal ion channel dysfunction. Dysfunctional ion channels can cause hyperexcitability in neurons, which in turn produces seizures. The team hopes to discover new molecular targets for antiepileptic drugs by dissecting the signaling pathways underlying ion channel dysfunction in epilepsy.

For more information on his research activities please see Nicholas Poolos' page on the Graduate Program in Neuroscience website

University of Washington • Center on Human Development and Disability • Box 357920 • Seattle WA 98195-7920 USA • 206-543-7701 • chdd@uw.edu