Personal Statement
The University of Washington provides an extraordinary environment for research, teaching and clinical practice. Here, I can participate in translational research that takes the innovations of the laboratory into the clinic to assist in the diagnosis and treatment of vestibular and oculomotor disorders in adults and children. I can study motor and sensory function in humans, and using basic biological models. I can see patients in the clinic, and teach undergraduates, graduate students, and residents. I have an opportunity to collaborate with some of the finest researchers in the world. How cool is that! (More about James O. Phillips)
Affiliations:
- Department of Ophthalmology
- Department of Otolaryngology-HNS
- Department of Psychology
- Human Interface Technology Laboratory
- Virginia Merrill Bloedel Hearing Research Center
- Washington National Primate Research Center
Research Interests:
- Adaptation and learning in human and non-human primates
- Brainstem control of oculomotor function and vestibular sensation.
- Comparative biology of vestibular function.
- Development of behavior in infants and children
- Genetic influences on vestibular and oculomotor function.
- Neural mechanisms of adaptation and learning
- Neurovestibular consequences of spaceflight
- Vestibular and oculomotor testing in the clinic
Professional Activities:
- Director, Dizziness and Balance Center,
- Director, Vestibular diagnostic Laboratory
- University of Washington Medical Center
- Director, Clinical Oculomotor Laboratory,
- Children's Hospital and Medical Center
- PI, NASA NNA04CC60G, Gravitational Influence on Cerebellar
- Control of Gaze Movement and Adaptation
- Co-PI, NAAR, Linking Cerebellar Pathology to Functioning in Individuals with Autism: Implications for Translational Research
Laboratories:
- Vestibular Diagnostic Laboratory, UWMC
- Clinical Oculomotor Laboratory, CHRMC
- Oculomotor/vestibular Genetic Translations Laboratory, WNPRC
- Infant Oculomotor Laboratory, CHDD
- Oculomotor Neurophysiology Laboratory, WNPRC
- Zebra Fish Electrophysiology Laboratory
Research Projects:
- Adaptation of human saccades.
- Linking Cerebellar Pathology
- Development of Gaze Shifts
- HEAR Group
- Vestibular and optokinetic testing for research and clinic.
- Oculomotor System Studies
- Electrical Stimulation of the vestibular nerve.
Recent Publications:
- Weiss, A.H., Phillips, J.O. Ophthalmoplegic migraine. Pediatric Neurology, 30:64-66, 2004
- Fuchs, A.F., Ling, L., Phillips, J.O. Behavior of the pvp interneurons of the vestibulo-ocular reflex during head-free gaze shifts in the monkey J Neurophysiol.94(6):4481-90, 2005
- Street, V.A., Kallman, J.C., Robertson, N.G., Kuo, S.F., Morton, C.C., Phillips, J.O. A novel DFNA9 mutation in the VWFA2 domain of COCH alters a conserved cysteine residue and intrachain disulfide bond formation resulting in progressive hearing loss and site-specific vestibular and central oculomotor dysfunction. American Journal of Medical Genetics, 139(2):86-95, 2005
- Weiss, A.H., Phillips, J.O. Congenital and compensated vestibular dysfunction in childhood: an overlooked entity. Pediatric Neurology, in press
- Weiss, A.H., Phillips, J.O. Hypertropia Associated with Lateral Translation of the Superior Rectus Muscle Pulley in Unilateral Coronal Synostosis. Archives of Ophthalmology, in press
Teaching:
- Psychology
- Speech and Hearing
- Ophthalmology Resident Education
- Otolaryngology Resident Education
