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Directory >> Christine Johnston, MD, MPH


Contact Information

Christine Johnston, MD, MPH

  • Assistant Professor, Division of Allergy and Infectious Disease
    Associate Medical Director, Virology Research Clinic
  • University of Washington

  • Research Affiliate
  • Fred Hutchinson Cancer Research Center

Dr. Johnston is a physician-scientist who performs clinical studies of genital herpes simplex virus type 2 (HSV-2) infection, focused on characterizing spatial localization of subclinical genital shedding and host-virus interactions. In addition, research interests include studies of existing and novel antiviral agents to suppress HSV-2 genital shedding, and the interactions between HSV-2 and coinfections in the female genital tract, specifically HIV-1 and bacterial vaginosis.

Selected Publications

Johnston C, Magaret A, Selke S, Remington M, Corey L, Wald A. Herpes simplex virus viremia during primary genital infection. J Infect Dis. 2008; 198(1): 31-4.
PubMed Abstract

Johnston C, Orem J, Okuku F, Kalinaki M, Saracino M, Mbidde-Katongole E. Impact of HIV infection and Kaposi Sarcoma on human herpesvirus-8 mucosal and replication and dissemination in Uganda. PLoS ONE. 2009; 4(1): e4222.
PubMed Abstract

Tronstein E, Johnston C, Huang M, et al. Genital shedding of herpes simplex virus among symptomatic and asymptomatic persons with HSV-2 infection. JAMA. 2011; 305(14): 1441-9.
PubMed Abstract

Johnston C, Koelle DM, Wald A. HSV-2: in pursuit of a vaccine. J Clin Invest. 2011; 121(12), 4600-9.
PubMed Abstract

Johnston C, Saracino M, Kuntz S, et al. Standard-dose and high-dose daily antiviral therapy for short episodes of genital HSV-2 reactivation: three randomised, open-label, cross-over trials. Lancet. 2012; 179(9816): 641-7.
PubMed Abstract

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