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Directory >> Mari M. Kitahata, MD, MPH


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Mari M. Kitahata, MD, MPH

  • Professor, Division of Allergy and Infectious Diseases, Department of Medicine
    University of Washington

Dr. Kitahata is Director of the University of Washington (UW) Center for AIDS Research (CFAR) Clinical Epidemiology and Health Services Research (CE&HSR) Core and the PI of the UW HIV Cohort, a prospective observational study of HIV-infected patients in care at UW, the largest single provider of HIV care in the northwestern US and an HIV/AIDS center of excellence. The CE&HSR Core developed the UW HIV Information System (UWHIS) to integrate comprehensive clinical data on the UW HIV Cohort including demographic, medication, laboratory (e.g. CD4+ T cell count, HIV-1 RNA level, viral resistance), diagnosis, and patient-reported data (e.g. substance use, adherence), linked to biological specimens stored in the UW HIV Specimen Repository to support clinical, epidemiological, basic and translational HIV research.

Dr. Kitahata's research focuses on improving HIV outcomes and has elucidated key determinants of increased survival among HIV-infected individuals including physician HIV expertise and early initiation of antiretroviral treatment. She helped establish networks of national and international HIV research collaborations to address critical questions in HIV treatment and outcomes that can not be addressed through single cohorts or clinical trials that include examining factors associated with the increasing incidence of serious HIV-associated co-morbidities such as cardiovascular, renal and liver disease.

Dr. Kitahata is the UW PI of the CFAR Network of Integrated Clinical Systems (CNICS) and directs the CNICS Data Core that developed the CNICS Repository integrating comprehensive data on >30,000 patients from eight CFARs across the US (UW, UAB, UCSD, UCSF, CWRU, Harvard/Fenway, Johns Hopkins, UNC). Dr. Kitahata is the UW PI of the NIH-funded North American AIDS Cohort Collaboration on Research and Design (NA-ACCORD) region of the global International Epidemiologic Databases to Evaluate AIDS (IeDEA) project and directs the NA-ACCORD Data Core that merges clinical data on >130,000 HIV-infected individuals in care at >200 sites across the US and Canada. These unique research platforms (UWHIS, CNICS and NA-ACCORD) support a wide range of innovative interdisciplinary HIV/AIDS research..

Selected Publications

Kitahata MM, Gange SJ, Abraham AG, et al. Effect of early versus deferred antiretroviral therapy for HIV on survival. N Engl J Med. 2009; 360(18): 1815-26.
PubMed Abstract

Kitahata MM, Koepsell TD, Deyo RA, et al. Physicians' experience with the acquired immunodeficiency syndrome as a factor in patients' survival. N Engl J Med. 1996; 334(11): 701-6.
PubMed Abstract

Kitahata MM, Rodriguez B, Haubrich R, et al. Cohort profile: the Centers for AIDS Research Network of Integrated Clinical Systems. Int J Epidemiol. 2008; 37(5): 948-55.
Link to PubMed

Gange SJ, Kitahata MM, Saag MS, Bangsberg DR, Bosch RJ, Brooks JT, Calzavara L, Deeks SG, Eron JJ, Gebo KA, John Gill M, Haas DW, Hogg RS, Horberg MA, Jacobson LP, Justice AC, Kirk GD, Klein MB, Martin JN, McKaig RG, Rodriguez B, Rourke SB, Sterling TR, Freeman AM, Moore RD. Cohort Profile: The North American AIDS Cohort Collaboration on Research and Design (NA-ACCORD). Int J Epidemiol. 8 Jan 2007; 36(2):294-301.
Link to PubMed

Dombrowski JC, Kitahata MM, Van Rompaey SE, Crane HM, Mugavero MJ, Eron JJ, Boswell SL, Rodriguez B, Mathews WC, Martin JN, Moore RD, Golden MR. High levels of antiretroviral use and viral suppression among persons in HIV care in the United States, 2010. J Acquir Immune Defic Syndr. Jul 1 2013;63(3):299-306.
Link to PubMed

Kim HN, Rodriguez CV, Van Rompaey S, Eron JJ, Thio CL, Crane HM, Overton ET, Saag MS, Martin J, Geng E, Mugavero M, Rodriguez B, Mathews WC, Boswell S, Moore R, Kitahata MM; for the Centers for AIDS Research Network of Integrated Clinical Systems (CNICS). Factors associated with delayed hepatitis B viral suppression on tenofovir among HBV-HIV coinfected patients in the CNICS cohort. J Acquir Immune Defic Syndr. 2014 Feb 3. [Epub ahead of print]
Link to PubMed

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