{"id":69,"date":"2020-04-30T13:46:53","date_gmt":"2020-04-30T20:46:53","guid":{"rendered":"https:\/\/depts.washington.edu\/doxypepstudy\/?page_id=69"},"modified":"2022-05-19T19:43:25","modified_gmt":"2022-05-20T02:43:25","slug":"about","status":"publish","type":"page","link":"https:\/\/depts.washington.edu\/doxypepstudy\/about\/","title":{"rendered":"About"},"content":{"rendered":"

The DoxyPEP study is now closed to enrollment. If you are a current or former study participant, please reach out to the study team for more information.<\/strong><\/p>\n

The Doxy PEP study was organized as a response to the high rates of syphilis, gonorrhea and chlamydia among men who have sex with men and transgender women in the US.<\/p>\n

\"DoxyPEP<\/a><\/p>\n

DoxyPEP campaign poster<\/span><\/p>\n<\/div>\n

Preliminary findings from a French study done in 2017 suggests that doxycycline taken 24-72 hours after condomless sex (as post-exposure prophylaxis or PEP), reduced new cases of syphilis and chlamydia by 70% but had no effect on reducing gonorrhea.\u00a0 Over half of gonorrhea is resistance to doxycycline in France, and about one quarter of gonorrhea in the US is as well.<\/p>\n

In order to guide policy about doxycycline PEP for STI prevention, we need more information about doxycycline PEP\u2019s effectiveness, safety and effect on antimicrobial resistance in both men who have sex with men (MSM) and\u00a0 transgender women (TGW) living with HIV, in addition to MSM and TGW on PrEP.<\/p>\n

We designed the doxyPEP study to learn whether doxycycline PEP reduces syphilis, chlamydia and gonorrhea among MSM and TGW on PrEP and those living with HIV.\u00a0 We also are studying the effect on antimicrobial resistance, specifically whether intermittent use of doxycycline as PEP leads to resistance in gonorrhea, chlamydia and syphilis, Staph Aureus and other bacteria that we commonly carry.<\/p>\n","protected":false},"excerpt":{"rendered":"

The Doxy PEP study was organized as a response to the high rates of syphilis, gonorrhea and chlamydia among men who have sex with men and transgender women in the US. Preliminary findings from a French study done in 2017 suggests that doxycycline taken 24-72 hours after condomless sex (as post-exposure prophylaxis or PEP), reduced…<\/p>\n

Read more<\/a><\/div>\n","protected":false},"author":2,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"footnotes":""},"class_list":["post-69","page","type-page","status-publish","hentry"],"_links":{"self":[{"href":"https:\/\/depts.washington.edu\/doxypepstudy\/wp-json\/wp\/v2\/pages\/69","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/depts.washington.edu\/doxypepstudy\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/depts.washington.edu\/doxypepstudy\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/depts.washington.edu\/doxypepstudy\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/depts.washington.edu\/doxypepstudy\/wp-json\/wp\/v2\/comments?post=69"}],"version-history":[{"count":6,"href":"https:\/\/depts.washington.edu\/doxypepstudy\/wp-json\/wp\/v2\/pages\/69\/revisions"}],"predecessor-version":[{"id":144,"href":"https:\/\/depts.washington.edu\/doxypepstudy\/wp-json\/wp\/v2\/pages\/69\/revisions\/144"}],"wp:attachment":[{"href":"https:\/\/depts.washington.edu\/doxypepstudy\/wp-json\/wp\/v2\/media?parent=69"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}