Changho Chun is a graduate student in the Department of Bioengineering.
- Aim 1. Investigate the neuroprotective role of normal astrocyte-derived extracellular vesicles on neuronal survival
- and function (published, 2021)
- Aim 2. Investigate the physiologic effect and mode of astrocyte-mediated neuromodulation in normal and ALS mutant condition,and identify molecular drivers of the observed phenotypic change using human iPSC-derived spinal astrocytes and motor neurons.
- Aim 3. Assess physiological relevance of the iPSC-spinal motor neurons by comparing transcriptomic trajectories of differentiating in vitro culture to that of the developing human spinal cord
