{"id":309,"date":"2020-03-15T05:29:09","date_gmt":"2020-03-15T05:29:09","guid":{"rendered":"https:\/\/depts.washington.edu\/eph\/wordpress\/?page_id=309"},"modified":"2022-01-18T18:32:03","modified_gmt":"2022-01-19T02:32:03","slug":"changho-chun","status":"publish","type":"page","link":"https:\/\/depts.washington.edu\/eph\/wordpress\/the-team\/changho-chun\/","title":{"rendered":"Changho Chun"},"content":{"rendered":"\n<div class=\"wp-block-media-text alignwide is-stacked-on-mobile is-vertically-aligned-top\" style=\"grid-template-columns:18% auto\"><figure class=\"wp-block-media-text__media\"><img data-recalc-dims=\"1\" loading=\"lazy\" decoding=\"async\" width=\"204\" height=\"234\" src=\"https:\/\/i0.wp.com\/depts.washington.edu\/eph\/wordpress\/wp-content\/uploads\/2022\/01\/changho.jpg?resize=204%2C234&#038;ssl=1\" alt=\"\" class=\"wp-image-1026 size-full\"\/><\/figure><div class=\"wp-block-media-text__content\">\n<p class=\"has-drop-cap has-normal-font-size\">Changho Chun is a graduate student in the Department of Bioengineering.<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Aim 1. Investigate the neuroprotective role of normal astrocyte-derived extracellular vesicles on neuronal survival<\/li><li>and function (published, 2021)<\/li><li>Aim 2. Investigate the physiologic effect and mode of astrocyte-mediated neuromodulation in normal and ALS mutant condition,and identify molecular drivers of the observed phenotypic change using human iPSC-derived spinal astrocytes and motor neurons.<\/li><li>Aim 3. Assess physiological relevance of the iPSC-spinal motor neurons by comparing transcriptomic trajectories of differentiating in vitro culture to that of the developing human spinal cord<\/li><\/ul>\n<\/div><\/div>\n\n\n\n<figure class=\"wp-block-image size-large\"><img data-recalc-dims=\"1\" loading=\"lazy\" decoding=\"async\" width=\"1024\" height=\"325\" src=\"https:\/\/i0.wp.com\/depts.washington.edu\/eph\/wordpress\/wp-content\/uploads\/2022\/01\/changho-projects.png?resize=1024%2C325&#038;ssl=1\" alt=\"\" class=\"wp-image-1028\" srcset=\"https:\/\/i0.wp.com\/depts.washington.edu\/eph\/wordpress\/wp-content\/uploads\/2022\/01\/changho-projects.png?resize=1024%2C325&amp;ssl=1 1024w, https:\/\/i0.wp.com\/depts.washington.edu\/eph\/wordpress\/wp-content\/uploads\/2022\/01\/changho-projects.png?resize=300%2C95&amp;ssl=1 300w, https:\/\/i0.wp.com\/depts.washington.edu\/eph\/wordpress\/wp-content\/uploads\/2022\/01\/changho-projects.png?resize=768%2C244&amp;ssl=1 768w, https:\/\/i0.wp.com\/depts.washington.edu\/eph\/wordpress\/wp-content\/uploads\/2022\/01\/changho-projects.png?resize=1536%2C487&amp;ssl=1 1536w, https:\/\/i0.wp.com\/depts.washington.edu\/eph\/wordpress\/wp-content\/uploads\/2022\/01\/changho-projects.png?resize=2048%2C650&amp;ssl=1 2048w, https:\/\/i0.wp.com\/depts.washington.edu\/eph\/wordpress\/wp-content\/uploads\/2022\/01\/changho-projects.png?resize=500%2C159&amp;ssl=1 500w, https:\/\/i0.wp.com\/depts.washington.edu\/eph\/wordpress\/wp-content\/uploads\/2022\/01\/changho-projects.png?resize=800%2C254&amp;ssl=1 800w, https:\/\/i0.wp.com\/depts.washington.edu\/eph\/wordpress\/wp-content\/uploads\/2022\/01\/changho-projects.png?resize=1280%2C406&amp;ssl=1 1280w, https:\/\/i0.wp.com\/depts.washington.edu\/eph\/wordpress\/wp-content\/uploads\/2022\/01\/changho-projects.png?resize=1920%2C609&amp;ssl=1 1920w, https:\/\/i0.wp.com\/depts.washington.edu\/eph\/wordpress\/wp-content\/uploads\/2022\/01\/changho-projects.png?w=3000&amp;ssl=1 3000w\" sizes=\"auto, (max-width: 1000px) 100vw, 1000px\" \/><\/figure>\n\n\n\n<figure class=\"wp-block-image size-full\"><img data-recalc-dims=\"1\" loading=\"lazy\" decoding=\"async\" width=\"1024\" height=\"321\" src=\"https:\/\/i0.wp.com\/depts.washington.edu\/eph\/wordpress\/wp-content\/uploads\/2022\/01\/changhoastro.png?resize=1024%2C321&#038;ssl=1\" alt=\"\" class=\"wp-image-1030\" srcset=\"https:\/\/i0.wp.com\/depts.washington.edu\/eph\/wordpress\/wp-content\/uploads\/2022\/01\/changhoastro.png?w=1024&amp;ssl=1 1024w, https:\/\/i0.wp.com\/depts.washington.edu\/eph\/wordpress\/wp-content\/uploads\/2022\/01\/changhoastro.png?resize=300%2C94&amp;ssl=1 300w, https:\/\/i0.wp.com\/depts.washington.edu\/eph\/wordpress\/wp-content\/uploads\/2022\/01\/changhoastro.png?resize=768%2C241&amp;ssl=1 768w, https:\/\/i0.wp.com\/depts.washington.edu\/eph\/wordpress\/wp-content\/uploads\/2022\/01\/changhoastro.png?resize=500%2C157&amp;ssl=1 500w, https:\/\/i0.wp.com\/depts.washington.edu\/eph\/wordpress\/wp-content\/uploads\/2022\/01\/changhoastro.png?resize=800%2C251&amp;ssl=1 800w\" sizes=\"auto, (max-width: 1000px) 100vw, 1000px\" \/><figcaption><strong>Astrocytes<\/strong><\/figcaption><\/figure>\n\n\n\n<figure class=\"wp-block-image size-full\"><img data-recalc-dims=\"1\" loading=\"lazy\" decoding=\"async\" width=\"825\" height=\"257\" src=\"https:\/\/i0.wp.com\/depts.washington.edu\/eph\/wordpress\/wp-content\/uploads\/2022\/01\/spinal-neurons.png?resize=825%2C257&#038;ssl=1\" alt=\"\" class=\"wp-image-1031\" srcset=\"https:\/\/i0.wp.com\/depts.washington.edu\/eph\/wordpress\/wp-content\/uploads\/2022\/01\/spinal-neurons.png?w=825&amp;ssl=1 825w, https:\/\/i0.wp.com\/depts.washington.edu\/eph\/wordpress\/wp-content\/uploads\/2022\/01\/spinal-neurons.png?resize=300%2C93&amp;ssl=1 300w, https:\/\/i0.wp.com\/depts.washington.edu\/eph\/wordpress\/wp-content\/uploads\/2022\/01\/spinal-neurons.png?resize=768%2C239&amp;ssl=1 768w, https:\/\/i0.wp.com\/depts.washington.edu\/eph\/wordpress\/wp-content\/uploads\/2022\/01\/spinal-neurons.png?resize=500%2C156&amp;ssl=1 500w, https:\/\/i0.wp.com\/depts.washington.edu\/eph\/wordpress\/wp-content\/uploads\/2022\/01\/spinal-neurons.png?resize=800%2C249&amp;ssl=1 800w\" sizes=\"auto, (max-width: 825px) 100vw, 825px\" \/><figcaption>Spinal neurons<\/figcaption><\/figure>\n\n\n\n<figure class=\"wp-block-image size-large\"><img data-recalc-dims=\"1\" loading=\"lazy\" decoding=\"async\" width=\"1024\" height=\"720\" src=\"https:\/\/i0.wp.com\/depts.washington.edu\/eph\/wordpress\/wp-content\/uploads\/2022\/01\/ch.png?resize=1024%2C720&#038;ssl=1\" alt=\"\" class=\"wp-image-1032\" srcset=\"https:\/\/i0.wp.com\/depts.washington.edu\/eph\/wordpress\/wp-content\/uploads\/2022\/01\/ch.png?resize=1024%2C720&amp;ssl=1 1024w, https:\/\/i0.wp.com\/depts.washington.edu\/eph\/wordpress\/wp-content\/uploads\/2022\/01\/ch.png?resize=300%2C211&amp;ssl=1 300w, https:\/\/i0.wp.com\/depts.washington.edu\/eph\/wordpress\/wp-content\/uploads\/2022\/01\/ch.png?resize=768%2C540&amp;ssl=1 768w, https:\/\/i0.wp.com\/depts.washington.edu\/eph\/wordpress\/wp-content\/uploads\/2022\/01\/ch.png?resize=1536%2C1081&amp;ssl=1 1536w, https:\/\/i0.wp.com\/depts.washington.edu\/eph\/wordpress\/wp-content\/uploads\/2022\/01\/ch.png?resize=2048%2C1441&amp;ssl=1 2048w, https:\/\/i0.wp.com\/depts.washington.edu\/eph\/wordpress\/wp-content\/uploads\/2022\/01\/ch.png?resize=500%2C352&amp;ssl=1 500w, https:\/\/i0.wp.com\/depts.washington.edu\/eph\/wordpress\/wp-content\/uploads\/2022\/01\/ch.png?resize=800%2C563&amp;ssl=1 800w, https:\/\/i0.wp.com\/depts.washington.edu\/eph\/wordpress\/wp-content\/uploads\/2022\/01\/ch.png?resize=1280%2C901&amp;ssl=1 1280w, https:\/\/i0.wp.com\/depts.washington.edu\/eph\/wordpress\/wp-content\/uploads\/2022\/01\/ch.png?resize=1920%2C1351&amp;ssl=1 1920w\" sizes=\"auto, (max-width: 1000px) 100vw, 1000px\" \/><\/figure>\n","protected":false},"excerpt":{"rendered":"<p>Changho Chun is a graduate student in the Department of Bioengineering. Aim 1. Investigate the neuroprotective role of normal astrocyte-derived extracellular vesicles on neuronal survival and function (published, 2021) Aim 2. Investigate the physiologic effect and mode of astrocyte-mediated neuromodulation in normal and ALS mutant condition,and identify molecular drivers of the observed phenotypic change using [&hellip;]<\/p>\n","protected":false},"author":4,"featured_media":0,"parent":324,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"site-sidebar-layout":"default","site-content-layout":"default","ast-site-content-layout":"default","site-content-style":"default","site-sidebar-style":"default","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"","ast-breadcrumbs-content":"","ast-featured-img":"","footer-sml-layout":"","ast-disable-related-posts":"","theme-transparent-header-meta":"default","adv-header-id-meta":"","stick-header-meta":"","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","astra-migrate-meta-layouts":"default","ast-page-background-enabled":"default","ast-page-background-meta":{"desktop":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"ast-content-background-meta":{"desktop":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"footnotes":""},"class_list":["post-309","page","type-page","status-publish","hentry"],"jetpack_sharing_enabled":true,"_links":{"self":[{"href":"https:\/\/depts.washington.edu\/eph\/wordpress\/wp-json\/wp\/v2\/pages\/309","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/depts.washington.edu\/eph\/wordpress\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/depts.washington.edu\/eph\/wordpress\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/depts.washington.edu\/eph\/wordpress\/wp-json\/wp\/v2\/users\/4"}],"replies":[{"embeddable":true,"href":"https:\/\/depts.washington.edu\/eph\/wordpress\/wp-json\/wp\/v2\/comments?post=309"}],"version-history":[{"count":5,"href":"https:\/\/depts.washington.edu\/eph\/wordpress\/wp-json\/wp\/v2\/pages\/309\/revisions"}],"predecessor-version":[{"id":1034,"href":"https:\/\/depts.washington.edu\/eph\/wordpress\/wp-json\/wp\/v2\/pages\/309\/revisions\/1034"}],"up":[{"embeddable":true,"href":"https:\/\/depts.washington.edu\/eph\/wordpress\/wp-json\/wp\/v2\/pages\/324"}],"wp:attachment":[{"href":"https:\/\/depts.washington.edu\/eph\/wordpress\/wp-json\/wp\/v2\/media?parent=309"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}