{"id":1286,"date":"2025-01-30T08:38:05","date_gmt":"2025-01-30T16:38:05","guid":{"rendered":"https:\/\/depts.washington.edu\/eph\/wordpress\/?p=1286"},"modified":"2025-01-30T08:38:05","modified_gmt":"2025-01-30T16:38:05","slug":"engineered-human-neuromuscular-junctions","status":"publish","type":"post","link":"https:\/\/depts.washington.edu\/eph\/wordpress\/engineered-human-neuromuscular-junctions\/","title":{"rendered":"Engineered human neuromuscular junctions"},"content":{"rendered":"\n

NDRG investigators, led by Alec Smith<\/a>, in collaboration with Curi Bio<\/a>, have just published a study creating engineered neuromuscular junctions from human induced pluripotent stem cells. Our platform enables simultaneous measurement of neuromuscular junction function across 24 engineered tissues! We’re now working with industry leaders to use this system as a means to remove animal testing from the development of botox products that are widely used in both the medical and cosmetic fields.<\/p>\n\n\n\n

https:\/\/www.sciencedirect.com\/science\/article\/pii\/S2666027X25000040?via%3Dihub#f0025<\/a><\/p>\n\n\n\n

\"\"<\/figure>\n","protected":false},"excerpt":{"rendered":"

NDRG investigators, led by Alec Smith, in collaboration with Curi Bio, have just published a study creating engineered neuromuscular junctions from human induced pluripotent stem cells. Our platform enables simultaneous measurement of neuromuscular junction function across 24 engineered tissues! We’re now working with industry leaders to use this system as a means to remove animal […]<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"site-sidebar-layout":"default","site-content-layout":"","ast-site-content-layout":"default","site-content-style":"default","site-sidebar-style":"default","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"","ast-breadcrumbs-content":"","ast-featured-img":"","footer-sml-layout":"","ast-disable-related-posts":"","theme-transparent-header-meta":"","adv-header-id-meta":"","stick-header-meta":"","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","astra-migrate-meta-layouts":"set","ast-page-background-enabled":"default","ast-page-background-meta":{"desktop":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"ast-content-background-meta":{"desktop":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"_jetpack_memberships_contains_paid_content":false,"footnotes":""},"categories":[8,5],"tags":[],"class_list":["post-1286","post","type-post","status-publish","format-standard","hentry","category-publications","category-research"],"jetpack_featured_media_url":"","jetpack_sharing_enabled":true,"_links":{"self":[{"href":"https:\/\/depts.washington.edu\/eph\/wordpress\/wp-json\/wp\/v2\/posts\/1286","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/depts.washington.edu\/eph\/wordpress\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/depts.washington.edu\/eph\/wordpress\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/depts.washington.edu\/eph\/wordpress\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/depts.washington.edu\/eph\/wordpress\/wp-json\/wp\/v2\/comments?post=1286"}],"version-history":[{"count":1,"href":"https:\/\/depts.washington.edu\/eph\/wordpress\/wp-json\/wp\/v2\/posts\/1286\/revisions"}],"predecessor-version":[{"id":1288,"href":"https:\/\/depts.washington.edu\/eph\/wordpress\/wp-json\/wp\/v2\/posts\/1286\/revisions\/1288"}],"wp:attachment":[{"href":"https:\/\/depts.washington.edu\/eph\/wordpress\/wp-json\/wp\/v2\/media?parent=1286"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/depts.washington.edu\/eph\/wordpress\/wp-json\/wp\/v2\/categories?post=1286"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/depts.washington.edu\/eph\/wordpress\/wp-json\/wp\/v2\/tags?post=1286"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}