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Matthew Thompson, MBChB, MPH, DPhil, MRCGP
Helen D. Cohen Endowed Professor and Vice Chair for Research, Family Medicine
Family Medicine Research Section

Biographical Information

Matthew Thompson is Professor of Family Medicine and Vice Chair for Research, and a practicing Family Doctor. He completed an NRSA Primary Care Research Fellowship and MPH at the University of Washington, and a DPhil from the University of Oxford. Within these he has used observational studies, trials of new interventions, systematic reviews and qualitative studies.

His current research interests are broad, but focus on areas of improving use of technology to improve diagnosis and monitoring for acute and chronic conditions in primary care. This includes diagnostic studies of new point of care blood tests, better ways of diagnosing and monitoring common conditions such as hypertension or atrial fibrillation, as well as clinical prediction rules for common conditions. In child health he has conducted some seminal work to improve knowledge about how primary care clinicians can better identify children presenting in primary care who have a serious illness from the large number who attend with self-limiting conditions. His research in infection has focussed on common respiratory infections- including targetting which adults and children are most likely to benefit from antibioitics or antivirals, the effectiveness of steroids for sore throats and sinusitis, and more accurate information about expected durations of common respiratory infections. Finally he has been involved in evidence syntheses and developing guidelines for the US Preventive Services Task Force, NICE in the UK, and the Cochrane Collaboration.

As Vice Chair for Research in the Department, his vision includes growing the size and scope of the Research Section, working closely with colleagues in the other Sections on research and scholarship, and increasing research collaborations across the WWAMI region and nationally.

Teaching Interests & Roles

-Evidence based medicine teaching for students, residents, clinicians and medical technology industry
-Diagnostic research study designs
-Systematic reviews of interventions, diagnostics, and observational studies.
-Research study design in primary care
-Clinical teaching related to pediatrics, infectious diseases in primary care, diagnostic test use, chronic disease management

Research Interests & Roles

-Diagnostic testing in primary care
-Improving monitoring of chronic disease
-Child health, including diagnosis of serious and common illnesses, use of antibioitics, management of respiratory tract infections
-Evidence syntheses and evidence based guideline development and implementation
-Global primary care related to child health and chronic disease management
-Improved use of new technology in primary care settings
-Research methods including cohort studies, diagnostic accuracy studies, qualitative, systematic reviews, RCTs

Current Projects

Development & Implementation of New Diagnostic Processes and Technologies in Primary Care

Trial of electronic IMCI and vital signs to improve detection of children with serious illness in Africa

Improving the pathways of care from primary care to the intensive care unit in Cape Town

RCT of steroids for treatment of adults with sore throat (Treatment Options without Antibiotics for Sore Throat (TOAST) trial

Monitoring long term conditions in primary care

Improving the recognition of type 1 and type 2 diabetes mellitus in children in primary care

A pilot study on the effects of adding C-reactive protein point of care testing in the management of acutely ill children in primary care

Effectiveness of Self Care strategies in Non-Communicable Diseases.

Improving the Use of Antibiotics for Children with Acute Respiratory Infections in Primary Care

Update and Amalgamation of Two Cochrane Reviews: Neuraminidase Inhibitors for Preventing and Treating Influenza in Healthy Adults and Children

Cohort study of adults presenting with suspected lower respiratory tract infection in primary care to determine predictors of hospital admission with pneumonia.