Annette L Fitzpatrick, PhD, MA
Research Professor, Family Medicine
Family Medicine Research Section
Phone: (206) 685-4295
e-mail: fitzpal@uw.edu


Biographical Profile

Annette Fitzpatrick, PhD, has been working in aging research for over 25 years in the field of epidemiology with a focus on cardiovascular disease and cognition. She has been leading the coordination of large multi-site studies of CVD and dementia as the first Program Director for the Cardiovascular Health Study (CHS) in 1990, and key investigator for the Multi-Ethnic Study of Atherosclerosis (MESA) and the Ginkgo Evaluation of Memory Study (GEMS). She is one of the founding members of the Collaborative Health Studies Coordinating Center in the Department of Biostatistics. Her expertise spans a wide range of methodologies including the development, conduct, and analysis of multi-site observational cohorts and clinical trials. Her own research has included ancillary studies to these large cohorts and independent studies funded by NIH, CDC and private foundations primarily focusing on coronary heart disease, stroke, dementia, cognitive decline, and functional aging. Dr. Fitzpatrick has been the PI or co-PI of multiple studies including: Cardiovascular Health Intervention Research and Translation Network (1 U48 DP000312-01), Telomeres and Biologic Aging (R01 HL80698-01), Domains of Inflammation and Risk of Dementia (R01 AT006668-01), Survival and Comorbidities after Dementia ( R03 AG21073), Epigenetics and Nutrition: DNA Methylation, Dietary Intake and CVD (R21HL104317), Use of Herbs and Dietary Supplements in Four Ethnicities (R21 AT002152), Neurological Manifestations of Cerebrovascular Disease in Vietnam (R21 TW008431), The Nepal Heart Health Pilot Study (UW Royalty Research Fund), The Dhulikehl Heart Study (Kathmandu University), Health Impact of the Dhanusha Community Drinking Water and Sanitation Project (Puget Sound Partners for Global Health). While the majority of her work has been carried out in the US, she has recently become involved in studies of chronic disease in low-resource settings including Vietnam, Nepal, Cambodia, Chile and Peru. Most recently Dr. Fitzpatrick helped lead the launch of the Dhulikhel Heart Study, designed to collect data on CVD risk factors but also incorporate the community into the local health care system in Nepal. Much of the work she has led or participated over the years is collaborative and her contributions to science have involved not only her own research but promotion of the work of others, especially new investigators and those residing in other countries. As an epidemiologist, providing expertise in study design, methods, and analysis has been a large part of these collaborations. Dr. Fitzpatrick's teaching role at UW has included development and instructing a course in Research Operations (EPI 587) and in mentoring students in writing grants (EPI 588). She has chaired the advisory committees for over 26 PhD and MS/MPH graduate students and been a member of committees for an additional 21 students over the past 15 years. She has presented seminars in the US and globally on her work. In Family Medicine, Dr. Fitzpatrick is the Co-Director of the NRSA Fellowship and welcomes opportunities to mentor new investigators or students in developing grant applications or manuscript publications.


Teaching Interests & Roles

EPI 587: Practical Issues in Research Operations
EPI 588 / HSERV 578: Preparing, Writing and Critiquing Scientific Research Proposals


Research Interests & Roles

Healthy Aging
Cardiovascular Disease and its Risk Factors
Hypertension
Diabetes
Physical Activity
Chronic Disease in Low Resource Settings
Global Health
Nepal
Vietnam
Cambodia
Chile
Peru


Scholarly Work

Selected Publications

Fitzpatrick AL, Powe NR, Cooper LS, Ives DG, Robbins JA. Barriers to health care access among the elderly and who perceives them. Am J Public Health 2004; 94:1788-1794.

Fitzpatrick AL, Kuller LH, Lopez LH, Kawas CH, Jagust W. Survival following dementia onset: Alzheimer’s disease and vascular dementia. J Neurol Sci 2005;229-230:43-49.

Fitzpatrick AL, Fried LP, Williamson J, Crowley P, Posey D, Kwong L, Bonk J, Moyer B, Chabot J, Kidoguchi L, DeKosky ST, Furberg C. Recruitment of the elderly into a pharmacologic prevention trial: The Ginkgo Evaluation of Memory Study. Contemporary Clinical Trials 2006; 27:541-553.

Fitzpatrick AL, Kronmal RA, Gardner JP, Psaty BM, Jenny NS, Tracy RP, Walston J, Kimura M, Aviv A. Leukocyte telomere length and cardiovascular disease in the Cardiovascular Health Study. Am J Epidemiol 2007;165:14-21.

Fitzpatrick, AL, Buchanan C, Nahin R, DeKosky S, Atkinson H, Carlson M, Williamson J. Associations of gait speed and other measures of physical function with cognition in a healthy cohort of the elderly. J Gerontol Med Sci 2007; 62A:1244-1251.

Velez JC, Fitzpatrick AL, Barbosa CI, Diaz M, Urzua M, Andrade AH. Nutritional status and obesity in children and young adults with disabilities in Punta Arenas (Pategonia), Chile. Int J Rehabil Res 2008; 31:305-13.

DeKosky ST, Williamson JD, Fitzpatrick AL, Kronmal RA, Ives DG, Saxton JA, Lopez OL, Burke G, Carlson MC, Fried LP, Kuller LH, Robbins JA, Tracy RP, Woolard NF, Dunn L, Snitz BE, Nahin RL, Furberg CD, for the Ginkgo Evaluation of Memory (GEM) Study Investigators. Ginkgo biloba for prevention of dementia: a randomized controlled trial. JAMA 2008;300:2253-2262.

Fitzpatrick AL, Kuller LH, Lopez OL, Diehr P, O’Meara ES, Longstreth WT, Luchsinger J. Mid- and late-life obesity: risk of dementia in the Cardiovascular Health Cognition Study. Arch Neurology 2009;66:336-42.

Fitzpatrick, AL, Buchanan C, Nahin R, DeKosky S, Atkinson H, Carlson M, Williamson J. Associations of gait speed and other measures of physical function with cognition in a healthy cohort of the elderly. J Gerontol Med Sci 2007; 62A:1244-1251.

Fitzpatrick AL, Kuller LH, Lopez OL, Diehr P, O’Meara ES, Longstreth WT, Luchsinger J. Mid- and late-life obesity: risk of dementia in the Cardiovascular Health Cognition Study. Arch Neurology 2009; 66:336-342.

Fitzpatrick AL, Steinman LE, Tu S-P, Ly KA, Ton TGN, Yip M-P, Sin M-K. Communicating with pictures: Perceptions of cardiovascular health in Asian immigrants. Am J Pub Health 2009; 99:2147-9.

Gelaye B, Revilla L, Lopez T, Suarez L, Sanchez SE, Hevner K, Fitzpatrick AL, Williams MA. Association between insulin resistance and c-reactive protein among Peruvian adults. Diabetol Metab Syndr 2010 2:30-36.

Fitzpatrick AL, Kronmal RA, Kimura M, Gardner JP, Psaty BM, Jenny NS, Tracy RP, Hardikar S, Aviv A. Leukocyte telomere length and mortality in the Cardiovascular Health Study. J Gerontol Med Sci 2011; 66:421-9.

Ton TG, Steinman L, Yip MP, Ly KA, Sin MK, Fitzpatrick AL, Tu SP. Knowledge of Cardiovascular Health Among Chinese, Korean and Vietnamese Immigrants to the US. J Immigr Minor Health. 2011; 13:127-39.

Fitzpatrick AL, Steinman LE, Tu SP, Ly KA, Ton TGN, Yip MP, Sin MK. Using Photovoice to understand cardiovascular health awareness in Asian elders. Health Promot Pract 2012; 13(1):48-54.

Fitzpatrick AL, Ngo QV, Ly KA, Ton TG, Longstreth WT, Vo TT, Heitzinger K, Pham CH, Tirschwell DL. Symptoms and risk factors for stroke in a community-based observational sample in Da Nang, Viet Nam. J Epidem Global Health. 2012;2(155-163).

Tirschwell DL, Ton TG, Ly KA, Van Ngo Q, Vo TT, Pham CH, Longstreth Jr WT, Fitzpatrick AL. A prospective cohort study of stroke characteristics, care, and mortality in a hospital stroke registry in Viet Nam. BMC Neurol. 2012;12(1):150.

An Y, Yi S, Fitzpatrick AL, Gupta V, Prak PR, Oum S, Logerfo JP. Appropriate body mass index and waist circumference cutoff for overweight and central obesity among adults in Cambodia. PloS one. 2013;8:e77897.

Ly KA, Ton TG, Ngo QV, Vo TT, Fitzpatrick AL. Double burden: a cross-sectional survey assessing factors associated with underweight and overweight status in Danang, Vietnam. BMC Public Health. 2013;13(1):35.

Fitzpatrick AL, Irizarry MC, Cushman M, Jenny NS, Chi GC, Koro C. Lipoprotein-associated phospholipase A2 and Risk of Dementia in the Cardiovascular Health Study. Atherosclerosis 2014; 235:384-391.

Fitzpatrick AL, Rapp SR, Luchsinger J, et al. T. Sociodemographic Correlates of Cognition in the Multi-Ethnic Study of Atherosclerosis (MESA). Am J Geriatr Psychiatry 2015; 23:684-697.

Snowden MB, Atkins DC, Steinman LE, Bell JF, Bryant LL, Copeland C, Fitzpatrick AL Longitudinal Association of Dementia and Depression. Am J Geriatr Psychiatry. 2014 Sep 21 (in press).

Greenwood-Hickman M, Rosenberg DE, Phelan EA, Fitzpatrick AL. Participation in Older Adult Physical Activity Programs and Risk for Falls Requiring Medical Care. Prev Chronic Dis (in press).

Shrestha A, Koirala B, Koju RP, Sharma D, Baidya SG, Gautam SP, Mukamal KJ, Karmacharya BM, Shakya S, Fitzpatrick AL. Dietary Patterns, Hypertension and Diabetes in Nepal – a Community-Based Study. Int J of Health and Nutrition (in press).


Additional publications:


http://www.ncbi.nlm.nih.gov/myncbi/browse/collection/47968265/?sort=date&direction=ascending


Education & Training

Institution

 

Degree or Credential

 

Year

University of Washington, Seattle PhD, Epidemiology 1999
Southern Illinois University MA, Zoology 1981
Loyola University, Chicago BS, Biology 1975