The Neurochip3 is a small biophysical signal recorder designed for open and closed loop stimulation experiments. Depending on the version of the Intan Technologies amplifier chip, data from 16 differential or 32 single-ended recording sites can be sampled at up to 20,000 samples per second and stored on a micro SD card for off-line analysis. Spike discrimination can be performed on up to 8 of these channels to drive spike-time dependent stimulation experiments.
Paper:
Neurochip3: An Autonomous Multichannel Bidirectional Brain-Computer Interface for Closed-Loop Activity-Dependent Stimulation, Front. Neurosci. 15:718465. doi: 10.3389/fnins.2021.718465. [PDF]
Download links:
Neurochip3 Power Point Presentation
Neurochip3 User's Manual (v3.32)
Neurochip3 Software CD (Neurochip3_v332.zip)
Older versions:
Neurochip3 User's Manual (v3.26)
Neurochip3 Software CD (Neurochip3_v323_2.zip)
Hardware Overview
- Biophysical signal amplifier with 32 single ended inputs
- 16-bit samples recorded at 5 kHz, 10 kHz, or 20 kHz
- 3 channel differential stimulator with 60 Volt compliance
- Micro SDCard slot for 32/64/128 GB data storage
- IrDA port for client communications
- Cyclone V FPGA to handle hardware devices and data streaming
- Atmel SAM4 MCU to interface with the client and run the experiment setup
- 3-axis accelerometer
- Rechargeable battery packs for approximately 12 hours of operation with ability to combine two packs for 24 hour operation.
Firmware (FPGA and CPU)
- Collect summary data and single channel sweeps for client review
- 8 window discriminators / random event generators (uniform or exponential distributions)
- Continuous data streaming to the SDCard
- 8 programmable conditions each with a separate stimulation protocol
- Delayed stimulation for paired pulse experiments
- Activity dependent stimulation based on recent signal levels or firing rates
- Support for pulse trains up to 1000 Hz.
- Asymmetrical bi-phasic stimulation waveforms
- Electrode impedence testing
- Integrate and fire spiking neural network with up to 250 units and 2000 connections
Software
- MATLAB client interface for parameter setup and review of data collection in progress
- Data downloaded directly from SDCard to individual raw data files
- Review downloaded data files
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