{"id":17741,"date":"2025-03-19T10:50:41","date_gmt":"2025-03-19T17:50:41","guid":{"rendered":"https:\/\/depts.washington.edu\/globalwach\/?p=17741"},"modified":"2026-04-24T09:51:43","modified_gmt":"2026-04-24T16:51:43","slug":"researchers-present-the-latest-scientific-discoveries-in-hiv-research-at-croi-2025","status":"publish","type":"post","link":"https:\/\/depts.washington.edu\/globalwach\/2025\/03\/19\/researchers-present-the-latest-scientific-discoveries-in-hiv-research-at-croi-2025\/","title":{"rendered":"Researchers present the latest scientific discoveries in HIV research at CROI 2025"},"content":{"rendered":"<p>&nbsp;<\/p>\n<div id=\"attachment_17743\" class=\"wp-caption aligncenter\" style=\"width: 608px\"><img loading=\"lazy\" decoding=\"async\" class=\"wp-image-17743\" src=\"https:\/\/depts.washington.edu\/globalwach\/wordpress\/wp-content\/uploads\/2025\/03\/DGH_CROI-2025_560x380.jpeg\" alt=\"\" width=\"598\" height=\"406\" srcset=\"https:\/\/depts.washington.edu\/globalwach\/wordpress\/wp-content\/uploads\/2025\/03\/DGH_CROI-2025_560x380.jpeg 560w, https:\/\/depts.washington.edu\/globalwach\/wordpress\/wp-content\/uploads\/2025\/03\/DGH_CROI-2025_560x380-300x204.jpeg 300w, https:\/\/depts.washington.edu\/globalwach\/wordpress\/wp-content\/uploads\/2025\/03\/DGH_CROI-2025_560x380-375x254.jpeg 375w\" sizes=\"auto, (max-width: 598px) 100vw, 598px\" \/><\/p>\n<p class=\"wp-caption-text\"><em>Researchers from the US and Kenya at CROI 2025.<\/em><\/span><\/p>\n<\/div>\n<p>Global WACh researchers and collaborators participated in this year\u2019s Conference on Retroviruses and Opportunistic Infections (CROI), held from March 9th-12th in San Francisco, CA. They shared the latest discoveries in the HIV and Co-Infectious Through the Lifecycle research portfolio related to health outcomes among children exposed to HIV and ART in utero, HIV acquisition and prevention during pregnancy and breastfeeding, and preventative therapies to treat tuberculosis among people living with HIV.<!--more--><\/p>\n<p>&nbsp;<\/p>\n<p>&nbsp;<\/p>\n<div id=\"attachment_17744\" class=\"wp-caption aligncenter\" style=\"width: 613px\"><img loading=\"lazy\" decoding=\"async\" class=\"wp-image-17744\" src=\"https:\/\/depts.washington.edu\/globalwach\/wordpress\/wp-content\/uploads\/2025\/03\/Njuguna_CROI2025-scaled.jpg\" alt=\"\" width=\"603\" height=\"452\" srcset=\"https:\/\/depts.washington.edu\/globalwach\/wordpress\/wp-content\/uploads\/2025\/03\/Njuguna_CROI2025-scaled.jpg 2560w, https:\/\/depts.washington.edu\/globalwach\/wordpress\/wp-content\/uploads\/2025\/03\/Njuguna_CROI2025-300x225.jpg 300w, https:\/\/depts.washington.edu\/globalwach\/wordpress\/wp-content\/uploads\/2025\/03\/Njuguna_CROI2025-1024x769.jpg 1024w, https:\/\/depts.washington.edu\/globalwach\/wordpress\/wp-content\/uploads\/2025\/03\/Njuguna_CROI2025-768x577.jpg 768w, https:\/\/depts.washington.edu\/globalwach\/wordpress\/wp-content\/uploads\/2025\/03\/Njuguna_CROI2025-1536x1153.jpg 1536w, https:\/\/depts.washington.edu\/globalwach\/wordpress\/wp-content\/uploads\/2025\/03\/Njuguna_CROI2025-2048x1538.jpg 2048w, https:\/\/depts.washington.edu\/globalwach\/wordpress\/wp-content\/uploads\/2025\/03\/Njuguna_CROI2025-375x282.jpg 375w, https:\/\/depts.washington.edu\/globalwach\/wordpress\/wp-content\/uploads\/2025\/03\/Njuguna_CROI2025-750x563.jpg 750w, https:\/\/depts.washington.edu\/globalwach\/wordpress\/wp-content\/uploads\/2025\/03\/Njuguna_CROI2025-1140x856.jpg 1140w, https:\/\/depts.washington.edu\/globalwach\/wordpress\/wp-content\/uploads\/2025\/03\/Njuguna_CROI2025-108x81.jpg 108w\" sizes=\"auto, (max-width: 603px) 100vw, 603px\" \/><\/p>\n<p class=\"wp-caption-text\"><em>Dr. Irene Njuguna presenting at CROI 2025 on March 10th.<\/em><\/span><\/p>\n<\/div>\n<p>Dr. Irene Njuguna, researcher with appointments at Global WACh and Kenyatta National Hospital, presented a symposia talk titled, <strong>\u201cHIV Care Continuum in Children: successes, gaps, and the future\u201d<\/strong> in the \u201cFilling the Gaps: Challenges and Opportunities in the Care of Children and Youth With Perinatal HIV\u201d symposium.\u00a0 The talk highlighted evidence-based opportunities for intervention to improve HIV testing, treatment initiation and viral suppression among children living with HIV and summarized key research gaps.<\/p>\n<p>&nbsp;<\/p>\n<p>&nbsp;<\/p>\n<div id=\"attachment_17745\" class=\"wp-caption aligncenter\" style=\"width: 610px\"><img loading=\"lazy\" decoding=\"async\" class=\"wp-image-17745\" src=\"https:\/\/depts.washington.edu\/globalwach\/wordpress\/wp-content\/uploads\/2025\/03\/Kinutha_CROI2025.jpeg\" alt=\"\" width=\"600\" height=\"450\" srcset=\"https:\/\/depts.washington.edu\/globalwach\/wordpress\/wp-content\/uploads\/2025\/03\/Kinutha_CROI2025.jpeg 1600w, https:\/\/depts.washington.edu\/globalwach\/wordpress\/wp-content\/uploads\/2025\/03\/Kinutha_CROI2025-300x225.jpeg 300w, https:\/\/depts.washington.edu\/globalwach\/wordpress\/wp-content\/uploads\/2025\/03\/Kinutha_CROI2025-1024x768.jpeg 1024w, https:\/\/depts.washington.edu\/globalwach\/wordpress\/wp-content\/uploads\/2025\/03\/Kinutha_CROI2025-768x576.jpeg 768w, https:\/\/depts.washington.edu\/globalwach\/wordpress\/wp-content\/uploads\/2025\/03\/Kinutha_CROI2025-1536x1152.jpeg 1536w, https:\/\/depts.washington.edu\/globalwach\/wordpress\/wp-content\/uploads\/2025\/03\/Kinutha_CROI2025-375x281.jpeg 375w, https:\/\/depts.washington.edu\/globalwach\/wordpress\/wp-content\/uploads\/2025\/03\/Kinutha_CROI2025-750x563.jpeg 750w, https:\/\/depts.washington.edu\/globalwach\/wordpress\/wp-content\/uploads\/2025\/03\/Kinutha_CROI2025-1140x855.jpeg 1140w, https:\/\/depts.washington.edu\/globalwach\/wordpress\/wp-content\/uploads\/2025\/03\/Kinutha_CROI2025-108x81.jpeg 108w\" sizes=\"auto, (max-width: 600px) 100vw, 600px\" \/><\/p>\n<p class=\"wp-caption-text\"><em>Dr. John Kinuthia presenting at CROI 2025 on March 11th.<\/em><\/span><\/p>\n<\/div>\n<p>Dr. John Kinuthia, obstetrician gynecologist and Head of Research and Programs at Kenyatta National Hospital, gave a plenary talk titled, <strong>\u201cHIV in Pregnancy and Breastfeeding.\u201d<\/strong> The talk highlighted significant progress in accelerating PrEP treatment to pregnant and breastfeeding women, including contribution from GWACh PrEP work in Kenya, and evidence-based models to improve uptake.<\/p>\n<p>Both talks highlighted the significant contribution of PEPFAR in accelerating access to HIV care in low resource settings.<\/p>\n<p>Eight poster abstracts developed by our researchers and collaborators are listed below.<\/p>\n<h3>Accepted Abstracts<\/h3>\n<table>\n<tbody>\n<tr>\n<td width=\"206\"><strong>Title<\/strong><\/td>\n<td width=\"158\"><strong>Presenting Author<\/strong><\/td>\n<td width=\"328\"><strong>Authors<\/strong><\/td>\n<\/tr>\n<tr>\n<td width=\"206\"><a href=\"https:\/\/www.croiconference.org\/abstract\/3254-2025\/\">Comparing Telomere Length Between Children Who Were and Were Not Exposed to HIV in Kenya<\/a><\/td>\n<td width=\"158\">Jillian Neary<\/p>\n<p>University of Washington<\/td>\n<td width=\"328\">Jillian Neary, Irene Njuguna, Tiffany Pan, Daniel Matemo, Fiona McBride, Alvin Onyango, Maureen King&#8217;e, Prestone O. Owiti, Celestine Adogo, Dalton Wamalwa, Dan T. A. Eisenberg, Grace John-Stewart<\/td>\n<\/tr>\n<tr>\n<td width=\"206\"><a href=\"https:\/\/www.croiconference.org\/abstract\/2492-2025\/\" target=\"_blank\" rel=\"noopener\">HIV Exposure Does Not Affect Cytomegalovirus Acquisition Risk in a Setting of Optimized Maternal ART<\/a><\/td>\n<td width=\"158\">Emily Begnel<\/p>\n<p>University of Washington<\/td>\n<td width=\"328\">Emily R. Begnel, Mi-Suk Kang Dufour, Kerusha Govender, Jing Hu, Elisabeth McClymont, Ednah Ojee, Prestone Owiti, Judith Adhiambo, Eliza Mabele, Bhavna H. Chohan, Dara A. Lehman, John Kinuthia, Dalton Wamalwa, Soren Gantt, Jennifer Slyker<\/td>\n<\/tr>\n<tr>\n<td width=\"206\"><a href=\"https:\/\/www.croiconference.org\/abstract\/1407-2025\/\" target=\"_blank\" rel=\"noopener\">HIV Exposure Affects Gut Virome Richness but Not Diversity Among Kenyan Infants<\/a><\/td>\n<td width=\"158\">Emily Begnel<\/p>\n<p>University of Washington<\/td>\n<td width=\"328\">Emily R. Begnel, Rabia Maqsood, LaRinda A. Holland, Ednah Ojee, Prestone Owiti, Judith Adhiambo, Eliza Mabele, Soren Gantt, Bhavna H. Chohan, John Kinuthia, Dalton Wamalwa, Efrem S. Lim, Dara A. Lehman, Jennifer Slyker<\/td>\n<\/tr>\n<tr>\n<td width=\"206\"><a href=\"https:\/\/www.croiconference.org\/abstract\/2471-2025\/\">Inflammatory Cytokines in ART-Naive Kenyan Children Diagnosed With HIV at Hospital Admission<\/a><\/td>\n<td width=\"158\">Emily Begnel<\/p>\n<p>University of Washington<\/td>\n<td width=\"328\">Lasata Shrestha, Irene Njuguna, Elizabeth M. Obimbo, Lisa Marie Cranmer, Emily R. Begnel, Daisy Chebet, Judith Adhiambo, Kenneth A. Tapia, Barbra Richardson, Hellen M. Okinyi, Cheryl Day, Grace John-Stewart, Dalton Wamalwa, Jennifer Slyker<\/td>\n<\/tr>\n<tr>\n<td width=\"206\"><a href=\"https:\/\/www.croiconference.org\/abstract\/718-2025\/\">Impact of Offering PrEP Choice on HIV Incidence in High-Risk Pregnant Women in Kenya<\/a><\/td>\n<td width=\"158\">Tessa Concepcion<\/p>\n<p>University of Washington<\/td>\n<td width=\"328\">Tessa Concepcion, John Kinuthia, Felix Abuna, Eunita Akim, Lauren A. Gomez, Emma Mukenyi, Nancy Ngumbau, Jerusha Mogaka, Ben Ochieng, Monisha Sharma, Grace John-Stewart, Jillian Pintye<\/td>\n<\/tr>\n<tr>\n<td width=\"206\"><a href=\"https:\/\/www.croiconference.org\/abstract\/3883-2025\/\">Prenatal PrEP Exposure and Language Development Among Children at 5 Years<\/a><\/td>\n<td width=\"158\">Laur\u00e9n Gom\u00e9z<\/p>\n<p>University of Washington<\/td>\n<td width=\"328\">Laur\u00e9n A. Gom\u00e9z, John Kinuthia, Felix Abuna, Sarah Benki, Mary Marwa, Salphine Watoyi, Bilhah Aomo, Nancy Ngumbau, Ben Ochieng, Anna Larsen, Joshua Stern, Barbra Richardson, Grace John-Stewart, Jillian Pintye<\/td>\n<\/tr>\n<tr>\n<td width=\"206\"><a href=\"https:\/\/www.croiconference.org\/abstract\/2807-2025\/\">STI Testing Is Associated With Lower PrEP Discontinuation Among Women Initiating PrEP in Pregnancy<\/a><\/td>\n<td width=\"158\">Jerusha Mogaka<\/p>\n<p>University of Washington<\/td>\n<td width=\"328\">Jerusha Mogaka, Felix Abuna, Eunita Akim, John Kinuthia, Lauren A. Gomez, Mary Marwa, Chelsea Morroni, Aamirah Mussa, Nancy Ngumbau, Celestine Adogo, Peter Okoth, Salphine Watoyi, Barbra Richardson, Grace John-Stewart, Jillian Pintye<\/td>\n<\/tr>\n<tr>\n<td width=\"206\"><a href=\"https:\/\/www.croiconference.org\/abstract\/2306-2025\/\">Weekly Rifapentine and Isoniazid (3HP) vs Isoniazid Preventive Therapy (6H) Among People With HIV<\/a><\/td>\n<td width=\"158\">Dickens Onyango<\/p>\n<p>Kisumu County Department of Health<\/td>\n<td width=\"328\">Dickens Onyango, Jerphason Mecha, Lilian N. Njagi, Samson Aoro, John Kinuthia, Grace John-Stewart, Sylvia LaCourse<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n","protected":false},"excerpt":{"rendered":"<p>&nbsp; Global WACh researchers and collaborators participated in this year\u2019s Conference on Retroviruses and Opportunistic Infections (CROI), held from March 9th-12th in San Francisco, CA. They shared the latest discoveries in the HIV and Co-Infectious Through the Lifecycle research portfolio related to health outcomes among children exposed to HIV and ART in utero, HIV acquisition&#8230;<\/p>\n<div><a class=\"more\" href=\"https:\/\/depts.washington.edu\/globalwach\/2025\/03\/19\/researchers-present-the-latest-scientific-discoveries-in-hiv-research-at-croi-2025\/\" aria-label=\"Read more about Researchers present the latest scientific discoveries in HIV research at CROI 2025\">Read more<\/a><\/div>\n","protected":false},"author":3,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[89,91,16],"tags":[],"class_list":["post-17741","post","type-post","status-publish","format-standard","hentry","category-hiv-and-co-infections","category-prep","category-research"],"_links":{"self":[{"href":"https:\/\/depts.washington.edu\/globalwach\/wp-json\/wp\/v2\/posts\/17741","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/depts.washington.edu\/globalwach\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/depts.washington.edu\/globalwach\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/depts.washington.edu\/globalwach\/wp-json\/wp\/v2\/users\/3"}],"replies":[{"embeddable":true,"href":"https:\/\/depts.washington.edu\/globalwach\/wp-json\/wp\/v2\/comments?post=17741"}],"version-history":[{"count":14,"href":"https:\/\/depts.washington.edu\/globalwach\/wp-json\/wp\/v2\/posts\/17741\/revisions"}],"predecessor-version":[{"id":19040,"href":"https:\/\/depts.washington.edu\/globalwach\/wp-json\/wp\/v2\/posts\/17741\/revisions\/19040"}],"wp:attachment":[{"href":"https:\/\/depts.washington.edu\/globalwach\/wp-json\/wp\/v2\/media?parent=17741"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/depts.washington.edu\/globalwach\/wp-json\/wp\/v2\/categories?post=17741"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/depts.washington.edu\/globalwach\/wp-json\/wp\/v2\/tags?post=17741"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}