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Education and Training:

Bachelor of Arts with Honors (1967), Washington State University, Pullman, WA

Doctor of Medicine (1972), University of Washington, Seattle, WA

Masters in Public Health (1979), University of Hawaii at Manoa, Honolulu, HI

Intern, Internal Medicine (1972-1973), Presbyterian-University Hospital, Pittsburgh, PA

Residency, Internal Medicine (1975-1977), Tripler Army Medical Center, Honolulu, HI

Fellowship, Hematology & Medical Oncology (1982-1985), Fitzsimons Army Medical Center, Aurora, CO

Graduate (1989), US Army Command and General Staff College

John R. Hess, MD, MPH, FACP, FAAAS
Professor of Laboratory Medicine and Hematology
University of Washington School of Medicine

Hess Office Address:
Harborview Medical Center
325 N Ninth Ave, Box 359743
Seattle, WA 98104

Phone:        (206) 744-6575
Fax:            (206) 744-6565
E-mail:        hessj3@u.washington.edu


Blood Coagulation, Transfusion in Trauma, Red Blood Cells


Red blood cell storage


Holcomb JB, Jenkins D, Rhee P, Johannigman J, Mahoney P, Metha S, Cox ED, Gehrke MJ, Beilman GJ, Schreiber M, Flaherty SF, Grathwohl KW, Spinella PC, Perkins JG, Beekley AC, McMullins NR, Park MS, Gonzales EA, Wade CE, Dubick MA, Schwab CW, Moore FA, Champion HR, Hoyt DB, Hess JR. Damage control resuscitation: Directly addressing the early coagulopathy of trauma. J Trauma 2007; 62: 307-310.

Hess JR, B, Brohi K, Dutton RP, Hauser CJ, Holcomb JB, Kluger Y, Mackway-Jones K, Parr MJ, Rizoli SB, Yurioka T, Hoyt DB, Bouillon B. The coagulopathy of trauma: A review of mechanisms. J Trauma 2008; 65:748-754.

Slichter SJ, Kaufman RM, Assmann SF, McCullough J, Triulzi DJ, Strauss RG, Gernsheimer TB, Ness PM, Brecher ME, Josephson CD, Konkle BA, Woodson RD, Ortel TL, Hillyer CD, Skerrett DL, McCrae KR, Sloan SR, Uhl L, George JN, Aquino VM, Manno C, McFarland JG, Hess JR, Leissinger C, Granger S. Dose of Prophylactic platelet transfusion and prevention of hemorrhage. N Engl J Med 2010; 362:600-613.

Hess JR, for the BEST Collaborative. Scientific problems in the regulation of red cell products. Transfusion 2012; 52:1827-1835.

Hess JR, Lelkens CCM, Holcomb JB, Scalea TM. Advances in military, field, and austere transfusion medicine in the last decade. Transfus Apheresis Sci 2013; 49:380-386.

Hess JR. Resuscitation of trauma-induced coagulopathy. Hematology 2013; 2013:664-667.

Stansbury LG, Hess AS, Thompson K, Kramer E, Scalea TM, Hess Jr. The clinical significance of platelet counts in the first 24 hours after severe injury. Transfusion 2013; 53(4):783-789.

Hess JR. Measures of stored red blood cell quality. Vox Sang 2014; 107:1-6.

Holcomb JB, Tilley BC, Baraniuk S, Fox EE, Wade CE, Podbielski JM, del Junco DJ, Brasel KJ, Bulger EM, Callcut RA, Cohen MJ, Cotton BA, Fabian TC, Inaba K, Kerby JD, Muskat P, O’Keeffe T, Rizoli S, Robinson BRH, Scalea TM, Schreiber MA, Stein DM, Weinberg JA, Callum JL, Hess JR, Matijevic N, Miller CN, Pittet J-F, Hoyt DB, Pearson GD, Leroux B, van Belle G for the PROPPR Study Group. Transfusion of plasma, platelets, and red blood cells in a 1:1:1 vs. a 1:1:2 ratio and mortality in patients with severe trauma: The PROPPR Randomized Clinical Trial. JAMA. 2015;313(5):483-494.

Novak DJ, Bai Y, Cooke RK, Marques MB, Fontaine MJ, Gottschall JL, Carey PM, Scanlan RM, Fiebig EW, Shulman IA, Nelson JM, Flax S, Duncan V, Daniel-Johnson JA, Callum J, Holcomb JB, Fox EE, Baraniuk S, Schreiber MA, Inaba K, Rizoli S, Podbielski J, Cotton BA, Hess JR on behalf of the PROPPR Study Group. Making thawed universal donor plasma available rapidly for massively bleeding trauma patients: the experience of the PROPPR trial centers. Transfusion 2015; 55:1331-1339.

Hess JR, Holcomb JB. Resuscitating PROPPRly. Transfusion 2015 Jun; 55:1362-1364.

Hess JR, Trachtenberg FL, Assmann SF, Triulzi DJ, Kaufman RM, Strauss RG, Granger S, Slichter SJ. Clinical and Laboratory Correlates of Platelet Alloimmunization and Refractoriness in the PLADO Trial. Vox Sang 2016; (In Press)