{"id":9,"date":"2021-10-12T11:24:36","date_gmt":"2021-10-12T18:24:36","guid":{"rendered":"https:\/\/depts.washington.edu\/impower22\/?page_id=9"},"modified":"2021-11-16T11:10:08","modified_gmt":"2021-11-16T19:10:08","slug":"about","status":"publish","type":"page","link":"https:\/\/depts.washington.edu\/impower22\/about\/","title":{"rendered":"About"},"content":{"rendered":"<p><div class=\"fusion-fullwidth fullwidth-box fusion-builder-row-1 fusion-flex-container fusion-parallax-none DesktopOnly nonhundred-percent-fullwidth non-hundred-percent-height-scrolling lazyload\" style=\"background-color: rgba(255,255,255,0);background-position: right top;background-repeat: no-repeat;border-width: 0px 0px 0px 0px;border-color:#e2e2e2;border-style:solid;-webkit-background-size:cover;-moz-background-size:cover;-o-background-size:cover;background-size:cover;\" data-bg=\"https:\/\/depts.washington.edu\/impower22\/wp-content\/uploads\/2021\/10\/about_header.jpg\" id=\"AboutHeroBg\" ><div class=\"fusion-builder-row fusion-row fusion-flex-align-items-flex-end fusion-flex-align-content-flex-end\" style=\"max-width:1210.56px;margin-left: calc(-4% \/ 2 );margin-right: calc(-4% \/ 2 );\"><div class=\"fusion-layout-column fusion_builder_column fusion-builder-column-0 fusion_builder_column_1_1 1_1 fusion-flex-column\"><div class=\"fusion-column-wrapper fusion-flex-justify-content-flex-start fusion-content-layout-column\" style=\"background-position:left top;background-repeat:no-repeat;-webkit-background-size:cover;-moz-background-size:cover;-o-background-size:cover;background-size:cover;padding: 0px 0px 0px 0px;\"><div class=\"fusion-text fusion-text-1 HeroText\"><h1>Women suffer the highest rates of HIV infection around the world. By participating in studies to find new, effective HIV prevention methods, you can help women everywhere.<\/h1>\n<\/div><\/div><style type=\"text\/css\">.fusion-body .fusion-builder-column-0{width:100% !important;margin-top : 0px;margin-bottom : 35px;}.fusion-builder-column-0 > .fusion-column-wrapper {padding-top : 0px !important;padding-right : 0px !important;margin-right : 1.92%;padding-bottom : 0px !important;padding-left : 0px !important;margin-left : 1.92%;}@media only screen and (max-width:1024px) {.fusion-body .fusion-builder-column-0{width:100% !important;order : 0;}.fusion-builder-column-0 > .fusion-column-wrapper {margin-right : 1.92%;margin-left : 1.92%;}}@media only screen and (max-width:767px) {.fusion-body .fusion-builder-column-0{width:100% !important;order : 0;}.fusion-builder-column-0 > .fusion-column-wrapper {margin-right : 1.92%;margin-left : 1.92%;}}<\/style><\/div><\/div><style type=\"text\/css\">.fusion-body .fusion-flex-container.fusion-builder-row-1{ padding-top : 0px;margin-top : 0px;padding-right : 0px;padding-bottom : 0px;margin-bottom : 0px;padding-left : 0px;min-height:400px;}<\/style><\/div><div class=\"fusion-fullwidth fullwidth-box fusion-builder-row-2 fusion-flex-container MobileOnly hundred-percent-fullwidth non-hundred-percent-height-scrolling\" style=\"background-color: rgba(255,255,255,0);background-position: center center;background-repeat: no-repeat;border-width: 0px 0px 0px 0px;border-color:#e2e2e2;border-style:solid;\" id=\"HeroMobile\" ><div class=\"fusion-builder-row fusion-row fusion-flex-align-items-flex-start\" style=\"width:104% !important;max-width:104% !important;margin-left: calc(-4% \/ 2 );margin-right: calc(-4% \/ 2 );\"><div class=\"fusion-layout-column fusion_builder_column fusion-builder-column-1 fusion_builder_column_1_1 1_1 fusion-flex-column GoldBg NoBotMarg\"><div class=\"fusion-column-wrapper fusion-flex-justify-content-flex-start fusion-content-layout-column\" style=\"background-position:left top;background-repeat:no-repeat;-webkit-background-size:cover;-moz-background-size:cover;-o-background-size:cover;background-size:cover;padding: 0px 0px 0px 0px;\"><div style=\"text-align:center;\"><span class=\" fusion-imageframe imageframe-none imageframe-1 hover-type-none NoBotMarg TwelveHundredOnly\"><img decoding=\"async\" width=\"1200\" height=\"300\" title=\"about_header\" src=\"https:\/\/depts.washington.edu\/impower22\/wp-content\/uploads\/2021\/10\/about_header.jpg\" data-orig-src=\"https:\/\/depts.washington.edu\/impower22\/wp-content\/uploads\/2021\/10\/about_header.jpg\" alt class=\"lazyload img-responsive wp-image-24\" srcset=\"data:image\/svg+xml,%3Csvg%20xmlns%3D%27http%3A%2F%2Fwww.w3.org%2F2000%2Fsvg%27%20width%3D%271200%27%20height%3D%27300%27%20viewBox%3D%270%200%201200%20300%27%3E%3Crect%20width%3D%271200%27%20height%3D%27300%27%20fill-opacity%3D%220%22%2F%3E%3C%2Fsvg%3E\" data-srcset=\"https:\/\/depts.washington.edu\/impower22\/wp-content\/uploads\/2021\/10\/about_header-200x50.jpg 200w, https:\/\/depts.washington.edu\/impower22\/wp-content\/uploads\/2021\/10\/about_header-400x100.jpg 400w, https:\/\/depts.washington.edu\/impower22\/wp-content\/uploads\/2021\/10\/about_header-600x150.jpg 600w, https:\/\/depts.washington.edu\/impower22\/wp-content\/uploads\/2021\/10\/about_header-800x200.jpg 800w, https:\/\/depts.washington.edu\/impower22\/wp-content\/uploads\/2021\/10\/about_header.jpg 1200w\" data-sizes=\"auto\" data-orig-sizes=\"(max-width: 767px) 100vw, 1200px\" \/><\/span><\/div><div style=\"text-align:center;\"><span class=\" fusion-imageframe imageframe-none imageframe-2 hover-type-none NoBotMarg SixFortyOnly\"><img decoding=\"async\" width=\"640\" height=\"249\" title=\"about_header_mobile\" src=\"https:\/\/depts.washington.edu\/impower22\/wp-content\/uploads\/2021\/10\/about_header_mobile.jpg\" data-orig-src=\"https:\/\/depts.washington.edu\/impower22\/wp-content\/uploads\/2021\/10\/about_header_mobile.jpg\" alt class=\"lazyload img-responsive wp-image-92\" srcset=\"data:image\/svg+xml,%3Csvg%20xmlns%3D%27http%3A%2F%2Fwww.w3.org%2F2000%2Fsvg%27%20width%3D%27640%27%20height%3D%27249%27%20viewBox%3D%270%200%20640%20249%27%3E%3Crect%20width%3D%27640%27%20height%3D%27249%27%20fill-opacity%3D%220%22%2F%3E%3C%2Fsvg%3E\" data-srcset=\"https:\/\/depts.washington.edu\/impower22\/wp-content\/uploads\/2021\/10\/about_header_mobile-200x78.jpg 200w, https:\/\/depts.washington.edu\/impower22\/wp-content\/uploads\/2021\/10\/about_header_mobile-400x156.jpg 400w, https:\/\/depts.washington.edu\/impower22\/wp-content\/uploads\/2021\/10\/about_header_mobile-600x233.jpg 600w, https:\/\/depts.washington.edu\/impower22\/wp-content\/uploads\/2021\/10\/about_header_mobile.jpg 640w\" data-sizes=\"auto\" data-orig-sizes=\"(max-width: 767px) 100vw, 640px\" \/><\/span><\/div><div class=\"fusion-text fusion-text-2 HeroText\"><h1>Women suffer the highest rates of HIV infection around the world. By participating in studies to find new, effective HIV prevention methods, you can help women everywhere.<\/h1>\n<\/div><\/div><style type=\"text\/css\">.fusion-body .fusion-builder-column-1{width:100% !important;margin-top : 0px;margin-bottom : 35px;}.fusion-builder-column-1 > .fusion-column-wrapper {padding-top : 0px !important;padding-right : 0px !important;margin-right : 1.92%;padding-bottom : 0px !important;padding-left : 0px !important;margin-left : 1.92%;}@media only screen and (max-width:1024px) {.fusion-body .fusion-builder-column-1{width:100% !important;order : 0;}.fusion-builder-column-1 > .fusion-column-wrapper {margin-right : 1.92%;margin-left : 1.92%;}}@media only screen and (max-width:767px) {.fusion-body .fusion-builder-column-1{width:100% !important;order : 0;}.fusion-builder-column-1 > .fusion-column-wrapper {margin-right : 1.92%;margin-left : 1.92%;}}<\/style><\/div><\/div><style type=\"text\/css\">.fusion-body .fusion-flex-container.fusion-builder-row-2{ padding-top : 0px;margin-top : 0px;padding-right : 0px;padding-bottom : 0px;margin-bottom : 0px;padding-left : 0px;}<\/style><\/div><div class=\"fusion-fullwidth fullwidth-box fusion-builder-row-3 fusion-flex-container TopSectionMarg nonhundred-percent-fullwidth non-hundred-percent-height-scrolling\" style=\"background-color: rgba(255,255,255,0);background-position: center center;background-repeat: no-repeat;border-width: 0px 0px 0px 0px;border-color:#e2e2e2;border-style:solid;\" id=\"AboutIntroBg\" ><div class=\"fusion-builder-row fusion-row fusion-flex-align-items-flex-start\" style=\"max-width:1210.56px;margin-left: calc(-4% \/ 2 );margin-right: calc(-4% \/ 2 );\"><div class=\"fusion-layout-column fusion_builder_column fusion-builder-column-2 fusion_builder_column_1_1 1_1 fusion-flex-column\"><div class=\"fusion-column-wrapper fusion-flex-justify-content-flex-start fusion-content-layout-column\" style=\"background-position:left top;background-repeat:no-repeat;-webkit-background-size:cover;-moz-background-size:cover;-o-background-size:cover;background-size:cover;padding: 0px 0px 0px 0px;\"><div class=\"fusion-text fusion-text-3\"><p>Pre-exposure prophylaxis, or PrEP, helps HIV-negative people protect themselves from getting HIV. PrEP medications work by preparing the body to block HIV before a person is exposed to it. The medication currently approved for PrEP use is a pill that is taken once a day.<\/p>\n<p><strong>But we know not everyone can take a pill every day.<\/strong><\/p>\n<p>This is your chance to help us understand if one pill per month can help prevent HIV.<\/p>\n<p>IMPOWER 22 is studying a new monthly PrEP pill called islatravir\u2014a small, powerful pill that could make protection against HIV much simpler. It looks very promising based on animal studies and is safe and well-tolerated in human studies. The next step is to see if it prevents HIV infection in humans. The IMPOWER 22 study will compare the efficacy and safety of monthly islatravir to daily emtricitabine\/tenofovir among cisgender women.<\/p>\n<\/div><\/div><style type=\"text\/css\">.fusion-body .fusion-builder-column-2{width:100% !important;margin-top : 0px;margin-bottom : 35px;}.fusion-builder-column-2 > .fusion-column-wrapper {padding-top : 0px !important;padding-right : 0px !important;margin-right : 1.92%;padding-bottom : 0px !important;padding-left : 0px !important;margin-left : 1.92%;}@media only screen and (max-width:1024px) {.fusion-body .fusion-builder-column-2{width:100% !important;order : 0;}.fusion-builder-column-2 > .fusion-column-wrapper {margin-right : 1.92%;margin-left : 1.92%;}}@media only screen and (max-width:767px) {.fusion-body .fusion-builder-column-2{width:100% !important;order : 0;}.fusion-builder-column-2 > .fusion-column-wrapper {margin-right : 1.92%;margin-left : 1.92%;}}<\/style><\/div><\/div><style type=\"text\/css\">.fusion-body .fusion-flex-container.fusion-builder-row-3{ padding-top : 0px;margin-top : 0px;padding-right : 0px;padding-bottom : 0px;margin-bottom : 0px;padding-left : 0px;}<\/style><\/div><div class=\"fusion-fullwidth fullwidth-box fusion-builder-row-4 fusion-flex-container nonhundred-percent-fullwidth non-hundred-percent-height-scrolling\" style=\"background-color: rgba(255,255,255,0);background-position: center center;background-repeat: no-repeat;border-width: 0px 0px 0px 0px;border-color:#e2e2e2;border-style:solid;\" id=\"AboutImage\" ><div class=\"fusion-builder-row fusion-row fusion-flex-align-items-flex-start\" style=\"max-width:1210.56px;margin-left: calc(-4% \/ 2 );margin-right: calc(-4% \/ 2 );\"><div class=\"fusion-layout-column fusion_builder_column fusion-builder-column-3 fusion_builder_column_1_1 1_1 fusion-flex-column\"><div class=\"fusion-column-wrapper fusion-flex-justify-content-flex-start fusion-content-layout-column\" style=\"background-position:left top;background-repeat:no-repeat;-webkit-background-size:cover;-moz-background-size:cover;-o-background-size:cover;background-size:cover;padding: 0px 0px 0px 0px;\"><div style=\"text-align:center;\"><span class=\" fusion-imageframe imageframe-none imageframe-3 hover-type-none\"><img decoding=\"async\" width=\"1164\" height=\"602\" title=\"about_image\" src=\"https:\/\/depts.washington.edu\/impower22\/wp-content\/uploads\/2021\/10\/about_image.png\" data-orig-src=\"https:\/\/depts.washington.edu\/impower22\/wp-content\/uploads\/2021\/10\/about_image.png\" alt class=\"lazyload img-responsive wp-image-34\" srcset=\"data:image\/svg+xml,%3Csvg%20xmlns%3D%27http%3A%2F%2Fwww.w3.org%2F2000%2Fsvg%27%20width%3D%271164%27%20height%3D%27602%27%20viewBox%3D%270%200%201164%20602%27%3E%3Crect%20width%3D%271164%27%20height%3D%27602%27%20fill-opacity%3D%220%22%2F%3E%3C%2Fsvg%3E\" data-srcset=\"https:\/\/depts.washington.edu\/impower22\/wp-content\/uploads\/2021\/10\/about_image-200x103.png 200w, https:\/\/depts.washington.edu\/impower22\/wp-content\/uploads\/2021\/10\/about_image-400x207.png 400w, https:\/\/depts.washington.edu\/impower22\/wp-content\/uploads\/2021\/10\/about_image-600x310.png 600w, https:\/\/depts.washington.edu\/impower22\/wp-content\/uploads\/2021\/10\/about_image-800x414.png 800w, https:\/\/depts.washington.edu\/impower22\/wp-content\/uploads\/2021\/10\/about_image.png 1164w\" data-sizes=\"auto\" data-orig-sizes=\"(max-width: 767px) 100vw, 1164px\" \/><\/span><\/div><\/div><style type=\"text\/css\">.fusion-body .fusion-builder-column-3{width:100% !important;margin-top : 0px;margin-bottom : 35px;}.fusion-builder-column-3 > .fusion-column-wrapper {padding-top : 0px !important;padding-right : 0px !important;margin-right : 1.92%;padding-bottom : 0px !important;padding-left : 0px !important;margin-left : 1.92%;}@media only screen and (max-width:1024px) {.fusion-body .fusion-builder-column-3{width:100% !important;order : 0;}.fusion-builder-column-3 > .fusion-column-wrapper {margin-right : 1.92%;margin-left : 1.92%;}}@media only screen and (max-width:767px) {.fusion-body .fusion-builder-column-3{width:100% !important;order : 0;}.fusion-builder-column-3 > .fusion-column-wrapper {margin-right : 1.92%;margin-left : 1.92%;}}<\/style><\/div><\/div><style type=\"text\/css\">.fusion-body .fusion-flex-container.fusion-builder-row-4{ padding-top : 0px;margin-top : 0px;padding-right : 0px;padding-bottom : 0px;margin-bottom : 0px;padding-left : 0px;}<\/style><\/div><div class=\"fusion-fullwidth fullwidth-box fusion-builder-row-5 fusion-flex-container SectionMargBottom nonhundred-percent-fullwidth non-hundred-percent-height-scrolling\" style=\"background-color: rgba(255,255,255,0);background-position: center center;background-repeat: no-repeat;border-width: 0px 0px 0px 0px;border-color:#e2e2e2;border-style:solid;\" id=\"GroupsBg\" ><div class=\"fusion-builder-row fusion-row fusion-flex-align-items-stretch\" style=\"max-width:1210.56px;margin-left: calc(-4% \/ 2 );margin-right: calc(-4% \/ 2 );\"><div class=\"fusion-layout-column fusion_builder_column fusion-builder-column-4 fusion_builder_column_1_1 1_1 fusion-flex-column NoBotMarg\"><div class=\"fusion-column-wrapper fusion-flex-justify-content-flex-start fusion-content-layout-column\" style=\"background-position:left top;background-repeat:no-repeat;-webkit-background-size:cover;-moz-background-size:cover;-o-background-size:cover;background-size:cover;padding: 0px 0px 0px 0px;\"><div class=\"fusion-text fusion-text-4\"><h2>Who can be in the IMPOWER study?<\/h2>\n<p>IMPOWER 22 is recruiting women aged 16 to 45 to join the study. About 4500 women will participate in this trial\u2014about 4000 women from<br \/>\nsites in Africa and 500 women from sites in the United States. See if you\u2019re in a <a href=\"https:\/\/depts.washington.edu\/impower22\/trial-locations\/\">location<\/a> where the study is being done.<\/p>\n<h2>How does the study work?<\/h2>\n<p>You will be randomly chosen to be in one of 2 groups.<\/p>\n<\/div><\/div><style type=\"text\/css\">.fusion-body .fusion-builder-column-4{width:100% !important;margin-top : 0px;margin-bottom : 35px;}.fusion-builder-column-4 > .fusion-column-wrapper {padding-top : 0px !important;padding-right : 0px !important;margin-right : 1.92%;padding-bottom : 0px !important;padding-left : 0px !important;margin-left : 1.92%;}@media only screen and (max-width:1024px) {.fusion-body .fusion-builder-column-4{width:100% !important;order : 0;}.fusion-builder-column-4 > .fusion-column-wrapper {margin-right : 1.92%;margin-left : 1.92%;}}@media only screen and (max-width:767px) {.fusion-body .fusion-builder-column-4{width:100% !important;order : 0;}.fusion-builder-column-4 > .fusion-column-wrapper {margin-right : 1.92%;margin-left : 1.92%;}}<\/style><\/div><div class=\"fusion-layout-column fusion_builder_column fusion-builder-column-5 fusion_builder_column_1_2 1_2 fusion-flex-column GroupInfoBg GroupInfoCol\"><div class=\"fusion-column-wrapper fusion-flex-justify-content-space-between fusion-content-layout-column\" style=\"background-position:left top;background-repeat:no-repeat;-webkit-background-size:cover;-moz-background-size:cover;-o-background-size:cover;background-size:cover;padding: 0px 0px 0px 0px;\"><div class=\"fusion-text fusion-text-5 WhiteText\"><h3>Group 1<\/h3>\n<p>Take the monthly pill (islatravir) plus a daily placebo pill.<\/p>\n<\/div><div style=\"text-align:center;\"><span class=\" fusion-imageframe imageframe-none imageframe-4 hover-type-none\"><img decoding=\"async\" width=\"389\" height=\"130\" title=\"group_image_1\" src=\"https:\/\/depts.washington.edu\/impower22\/wp-content\/uploads\/2021\/10\/group_image_1.png\" data-orig-src=\"https:\/\/depts.washington.edu\/impower22\/wp-content\/uploads\/2021\/10\/group_image_1.png\" alt class=\"lazyload img-responsive wp-image-35\" srcset=\"data:image\/svg+xml,%3Csvg%20xmlns%3D%27http%3A%2F%2Fwww.w3.org%2F2000%2Fsvg%27%20width%3D%27389%27%20height%3D%27130%27%20viewBox%3D%270%200%20389%20130%27%3E%3Crect%20width%3D%27389%27%20height%3D%27130%27%20fill-opacity%3D%220%22%2F%3E%3C%2Fsvg%3E\" data-srcset=\"https:\/\/depts.washington.edu\/impower22\/wp-content\/uploads\/2021\/10\/group_image_1-200x67.png 200w, https:\/\/depts.washington.edu\/impower22\/wp-content\/uploads\/2021\/10\/group_image_1.png 389w\" data-sizes=\"auto\" data-orig-sizes=\"(max-width: 767px) 100vw, 389px\" \/><\/span><\/div><\/div><style type=\"text\/css\">.fusion-body .fusion-builder-column-5{width:50% !important;margin-top : 0px;margin-bottom : 35px;}.fusion-builder-column-5 > .fusion-column-wrapper {padding-top : 0px !important;padding-right : 0px !important;margin-right : 3.84%;padding-bottom : 0px !important;padding-left : 0px !important;margin-left : 3.84%;}@media only screen and (max-width:1024px) {.fusion-body .fusion-builder-column-5{width:50% !important;order : 0;}.fusion-builder-column-5 > .fusion-column-wrapper {margin-right : 3.84%;margin-left : 3.84%;}}@media only screen and (max-width:767px) {.fusion-body .fusion-builder-column-5{width:100% !important;order : 0;}.fusion-builder-column-5 > .fusion-column-wrapper {margin-right : 1.92%;margin-left : 1.92%;}}<\/style><\/div><div class=\"fusion-layout-column fusion_builder_column fusion-builder-column-6 fusion_builder_column_1_2 1_2 fusion-flex-column GroupInfoBg GroupInfoCol\"><div class=\"fusion-column-wrapper fusion-flex-justify-content-space-between fusion-content-layout-column\" style=\"background-position:left top;background-repeat:no-repeat;-webkit-background-size:cover;-moz-background-size:cover;-o-background-size:cover;background-size:cover;padding: 0px 0px 0px 0px;\"><div class=\"fusion-text fusion-text-6 WhiteText\"><h3>Group 2<\/h3>\n<p>Take the daily emtricitabine\/tenofovir pill plus a monthly placebo pill.<\/p>\n<p>The placebos look exactly like islatravir or emtricitabine\/tenofovir but have no active ingredients. You, the study doctor, and the study staff will not know which study treatment group you are in.<\/p>\n<\/div><div style=\"text-align:center;\"><span class=\" fusion-imageframe imageframe-none imageframe-5 hover-type-none\"><img decoding=\"async\" width=\"313\" height=\"128\" title=\"group_image_2\" src=\"https:\/\/depts.washington.edu\/impower22\/wp-content\/uploads\/2021\/10\/group_image_2.png\" data-orig-src=\"https:\/\/depts.washington.edu\/impower22\/wp-content\/uploads\/2021\/10\/group_image_2.png\" alt class=\"lazyload img-responsive wp-image-36\" srcset=\"data:image\/svg+xml,%3Csvg%20xmlns%3D%27http%3A%2F%2Fwww.w3.org%2F2000%2Fsvg%27%20width%3D%27313%27%20height%3D%27128%27%20viewBox%3D%270%200%20313%20128%27%3E%3Crect%20width%3D%27313%27%20height%3D%27128%27%20fill-opacity%3D%220%22%2F%3E%3C%2Fsvg%3E\" data-srcset=\"https:\/\/depts.washington.edu\/impower22\/wp-content\/uploads\/2021\/10\/group_image_2-200x82.png 200w, https:\/\/depts.washington.edu\/impower22\/wp-content\/uploads\/2021\/10\/group_image_2.png 313w\" data-sizes=\"auto\" data-orig-sizes=\"(max-width: 767px) 100vw, 313px\" \/><\/span><\/div><\/div><style type=\"text\/css\">.fusion-body .fusion-builder-column-6{width:50% !important;margin-top : 0px;margin-bottom : 35px;}.fusion-builder-column-6 > .fusion-column-wrapper {padding-top : 0px !important;padding-right : 0px !important;margin-right : 3.84%;padding-bottom : 0px !important;padding-left : 0px !important;margin-left : 3.84%;}@media only screen and (max-width:1024px) {.fusion-body .fusion-builder-column-6{width:50% !important;order : 0;}.fusion-builder-column-6 > .fusion-column-wrapper {margin-right : 3.84%;margin-left : 3.84%;}}@media only screen and (max-width:767px) {.fusion-body .fusion-builder-column-6{width:100% !important;order : 0;}.fusion-builder-column-6 > .fusion-column-wrapper {margin-right : 1.92%;margin-left : 1.92%;}}<\/style><\/div><\/div><style type=\"text\/css\">.fusion-body .fusion-flex-container.fusion-builder-row-5{ padding-top : 0px;margin-top : 0px;padding-right : 0px;padding-bottom : 0px;margin-bottom : 0px;padding-left : 0px;}<\/style><\/div><div class=\"fusion-fullwidth fullwidth-box fusion-builder-row-6 fusion-flex-container SectionMargBottom nonhundred-percent-fullwidth non-hundred-percent-height-scrolling\" style=\"background-color: rgba(255,255,255,0);background-position: center center;background-repeat: no-repeat;border-width: 0px 0px 0px 0px;border-color:#e2e2e2;border-style:solid;\" id=\"AboutBoxesBg\" ><div class=\"fusion-builder-row fusion-row fusion-flex-align-items-stretch\" style=\"max-width:1210.56px;margin-left: calc(-4% \/ 2 );margin-right: calc(-4% \/ 2 );\"><div class=\"fusion-layout-column fusion_builder_column fusion-builder-column-7 fusion_builder_column_1_1 1_1 fusion-flex-column NoBotMarg\"><div class=\"fusion-column-wrapper fusion-flex-justify-content-flex-start fusion-content-layout-column\" style=\"background-position:left top;background-repeat:no-repeat;-webkit-background-size:cover;-moz-background-size:cover;-o-background-size:cover;background-size:cover;padding: 0px 0px 0px 0px;\"><div class=\"fusion-text fusion-text-7\"><h2>What else is important to know about IMPOWER?<\/h2>\n<\/div><\/div><style type=\"text\/css\">.fusion-body .fusion-builder-column-7{width:100% !important;margin-top : 0px;margin-bottom : 35px;}.fusion-builder-column-7 > .fusion-column-wrapper {padding-top : 0px !important;padding-right : 0px !important;margin-right : 1.92%;padding-bottom : 0px !important;padding-left : 0px !important;margin-left : 1.92%;}@media only screen and (max-width:1024px) {.fusion-body .fusion-builder-column-7{width:100% !important;order : 0;}.fusion-builder-column-7 > .fusion-column-wrapper {margin-right : 1.92%;margin-left : 1.92%;}}@media only screen and (max-width:767px) {.fusion-body .fusion-builder-column-7{width:100% !important;order : 0;}.fusion-builder-column-7 > .fusion-column-wrapper {margin-right : 1.92%;margin-left : 1.92%;}}<\/style><\/div><div class=\"fusion-layout-column fusion_builder_column fusion-builder-column-8 fusion_builder_column_1_3 1_3 fusion-flex-column AboutInfoBoxes\"><div class=\"fusion-column-wrapper lazyload fusion-flex-justify-content-flex-start fusion-content-layout-column\" style=\"background-position:center center;background-repeat:no-repeat;-webkit-background-size:cover;-moz-background-size:cover;-o-background-size:cover;background-size:cover;padding: 0px 0px 0px 0px;\" data-bg-url=\"https:\/\/depts.washington.edu\/impower22\/wp-content\/uploads\/2021\/10\/purple_card.png\" data-bg=\"https:\/\/depts.washington.edu\/impower22\/wp-content\/uploads\/2021\/10\/purple_card.png\"><div class=\"fusion-text fusion-text-8 WhiteText\"><h3>Timeline<\/h3>\n<p>You will be in this study for up to 3 years<\/p>\n<\/div><\/div><style type=\"text\/css\">.fusion-body .fusion-builder-column-8{width:33.333333333333% !important;margin-top : 0px;margin-bottom : 35px;}.fusion-builder-column-8 > .fusion-column-wrapper {padding-top : 0px !important;padding-right : 0px !important;margin-right : 5.76%;padding-bottom : 0px !important;padding-left : 0px !important;margin-left : 5.76%;}@media only screen and (max-width:1024px) {.fusion-body .fusion-builder-column-8{width:33.333333333333% !important;order : 0;}.fusion-builder-column-8 > .fusion-column-wrapper {margin-right : 5.76%;margin-left : 5.76%;}}@media only screen and (max-width:767px) {.fusion-body .fusion-builder-column-8{width:100% !important;order : 0;}.fusion-builder-column-8 > .fusion-column-wrapper {margin-right : 1.92%;margin-left : 1.92%;}}<\/style><\/div><div class=\"fusion-layout-column fusion_builder_column fusion-builder-column-9 fusion_builder_column_1_3 1_3 fusion-flex-column AboutInfoBoxes\"><div class=\"fusion-column-wrapper lazyload fusion-flex-justify-content-flex-start fusion-content-layout-column\" style=\"background-position:left top;background-repeat:no-repeat;-webkit-background-size:cover;-moz-background-size:cover;-o-background-size:cover;background-size:cover;padding: 0px 0px 0px 0px;\" data-bg-url=\"https:\/\/depts.washington.edu\/impower22\/wp-content\/uploads\/2021\/10\/red_card.png\" data-bg=\"https:\/\/depts.washington.edu\/impower22\/wp-content\/uploads\/2021\/10\/red_card.png\"><div class=\"fusion-text fusion-text-9 WhiteText\"><h3>Everyone takes medicine<\/h3>\n<p>Every participant will take a daily pill and a monthly pill. But only one of the pills will have the active medication<\/p>\n<\/div><\/div><style type=\"text\/css\">.fusion-body .fusion-builder-column-9{width:33.333333333333% !important;margin-top : 0px;margin-bottom : 35px;}.fusion-builder-column-9 > .fusion-column-wrapper {padding-top : 0px !important;padding-right : 0px !important;margin-right : 5.76%;padding-bottom : 0px !important;padding-left : 0px !important;margin-left : 5.76%;}@media only screen and (max-width:1024px) {.fusion-body .fusion-builder-column-9{width:33.333333333333% !important;order : 0;}.fusion-builder-column-9 > .fusion-column-wrapper {margin-right : 5.76%;margin-left : 5.76%;}}@media only screen and (max-width:767px) {.fusion-body .fusion-builder-column-9{width:100% !important;order : 0;}.fusion-builder-column-9 > .fusion-column-wrapper {margin-right : 1.92%;margin-left : 1.92%;}}<\/style><\/div><div class=\"fusion-layout-column fusion_builder_column fusion-builder-column-10 fusion_builder_column_1_3 1_3 fusion-flex-column AboutInfoBoxes\"><div class=\"fusion-column-wrapper lazyload fusion-flex-justify-content-flex-start fusion-content-layout-column\" style=\"background-position:left top;background-repeat:no-repeat;-webkit-background-size:cover;-moz-background-size:cover;-o-background-size:cover;background-size:cover;padding: 0px 0px 0px 0px;\" data-bg-url=\"https:\/\/depts.washington.edu\/impower22\/wp-content\/uploads\/2021\/10\/purple_card.png\" data-bg=\"https:\/\/depts.washington.edu\/impower22\/wp-content\/uploads\/2021\/10\/purple_card.png\"><div class=\"fusion-text fusion-text-10 WhiteText\"><h3>Voluntary<\/h3>\n<p>Being in this study is voluntary, and you can stop for any reason at any time<\/p>\n<\/div><\/div><style type=\"text\/css\">.fusion-body .fusion-builder-column-10{width:33.333333333333% !important;margin-top : 0px;margin-bottom : 35px;}.fusion-builder-column-10 > .fusion-column-wrapper {padding-top : 0px !important;padding-right : 0px !important;margin-right : 5.76%;padding-bottom : 0px !important;padding-left : 0px !important;margin-left : 5.76%;}@media only screen and (max-width:1024px) {.fusion-body .fusion-builder-column-10{width:33.333333333333% !important;order : 0;}.fusion-builder-column-10 > .fusion-column-wrapper {margin-right : 5.76%;margin-left : 5.76%;}}@media only screen and (max-width:767px) {.fusion-body .fusion-builder-column-10{width:100% !important;order : 0;}.fusion-builder-column-10 > .fusion-column-wrapper {margin-right : 1.92%;margin-left : 1.92%;}}<\/style><\/div><div class=\"fusion-layout-column fusion_builder_column fusion-builder-column-11 fusion_builder_column_1_3 1_3 fusion-flex-column AboutInfoBoxes\"><div class=\"fusion-column-wrapper lazyload fusion-flex-justify-content-flex-start fusion-content-layout-column\" style=\"background-position:left top;background-repeat:no-repeat;-webkit-background-size:cover;-moz-background-size:cover;-o-background-size:cover;background-size:cover;padding: 0px 0px 0px 0px;\" data-bg-url=\"https:\/\/depts.washington.edu\/impower22\/wp-content\/uploads\/2021\/10\/red_card.png\" data-bg=\"https:\/\/depts.washington.edu\/impower22\/wp-content\/uploads\/2021\/10\/red_card.png\"><div class=\"fusion-text fusion-text-11 WhiteText\"><h3>Free, monthly medical visits<\/h3>\n<p>You\u2019ll have monthly appointments that will include a check-up, as well as counseling, condoms, contraception, and STI testing<\/p>\n<\/div><\/div><style type=\"text\/css\">.fusion-body .fusion-builder-column-11{width:33.333333333333% !important;margin-top : 0px;margin-bottom : 35px;}.fusion-builder-column-11 > .fusion-column-wrapper {padding-top : 0px !important;padding-right : 0px !important;margin-right : 5.76%;padding-bottom : 0px !important;padding-left : 0px !important;margin-left : 5.76%;}@media only screen and (max-width:1024px) {.fusion-body .fusion-builder-column-11{width:33.333333333333% !important;order : 0;}.fusion-builder-column-11 > .fusion-column-wrapper {margin-right : 5.76%;margin-left : 5.76%;}}@media only screen and (max-width:767px) {.fusion-body .fusion-builder-column-11{width:100% !important;order : 0;}.fusion-builder-column-11 > .fusion-column-wrapper {margin-right : 1.92%;margin-left : 1.92%;}}<\/style><\/div><div class=\"fusion-layout-column fusion_builder_column fusion-builder-column-12 fusion_builder_column_1_3 1_3 fusion-flex-column AboutInfoBoxes\"><div class=\"fusion-column-wrapper lazyload fusion-flex-justify-content-flex-start fusion-content-layout-column\" style=\"background-position:left top;background-repeat:no-repeat;-webkit-background-size:cover;-moz-background-size:cover;-o-background-size:cover;background-size:cover;padding: 0px 0px 0px 0px;\" data-bg-url=\"https:\/\/depts.washington.edu\/impower22\/wp-content\/uploads\/2021\/10\/purple_card.png\" data-bg=\"https:\/\/depts.washington.edu\/impower22\/wp-content\/uploads\/2021\/10\/purple_card.png\"><div class=\"fusion-text fusion-text-12 WhiteText\"><h3>Experienced care<\/h3>\n<p>Your health will be closely monitored by an experienced team of clinicians and counselors while you are in this study<\/p>\n<\/div><\/div><style type=\"text\/css\">.fusion-body .fusion-builder-column-12{width:33.333333333333% !important;margin-top : 0px;margin-bottom : 35px;}.fusion-builder-column-12 > .fusion-column-wrapper {padding-top : 0px !important;padding-right : 0px !important;margin-right : 5.76%;padding-bottom : 0px !important;padding-left : 0px !important;margin-left : 5.76%;}@media only screen and (max-width:1024px) {.fusion-body .fusion-builder-column-12{width:33.333333333333% !important;order : 0;}.fusion-builder-column-12 > .fusion-column-wrapper {margin-right : 5.76%;margin-left : 5.76%;}}@media only screen and (max-width:767px) {.fusion-body .fusion-builder-column-12{width:100% !important;order : 0;}.fusion-builder-column-12 > .fusion-column-wrapper {margin-right : 1.92%;margin-left : 1.92%;}}<\/style><\/div><div class=\"fusion-layout-column fusion_builder_column fusion-builder-column-13 fusion_builder_column_1_3 1_3 fusion-flex-column AboutInfoBoxes\"><div class=\"fusion-column-wrapper lazyload fusion-flex-justify-content-flex-start fusion-content-layout-column\" style=\"background-position:left top;background-repeat:no-repeat;-webkit-background-size:cover;-moz-background-size:cover;-o-background-size:cover;background-size:cover;padding: 0px 0px 0px 0px;\" data-bg-url=\"https:\/\/depts.washington.edu\/impower22\/wp-content\/uploads\/2021\/10\/red_card.png\" data-bg=\"https:\/\/depts.washington.edu\/impower22\/wp-content\/uploads\/2021\/10\/red_card.png\"><div class=\"fusion-text fusion-text-13 WhiteText\"><h3>Reimbursement<\/h3>\n<p>You will be reimbursed for your study visits to offset transportation costs and expenses you incur<\/p>\n<\/div><\/div><style type=\"text\/css\">.fusion-body .fusion-builder-column-13{width:33.333333333333% !important;margin-top : 0px;margin-bottom : 35px;}.fusion-builder-column-13 > .fusion-column-wrapper {padding-top : 0px !important;padding-right : 0px !important;margin-right : 5.76%;padding-bottom : 0px !important;padding-left : 0px !important;margin-left : 5.76%;}@media only screen and (max-width:1024px) {.fusion-body .fusion-builder-column-13{width:33.333333333333% !important;order : 0;}.fusion-builder-column-13 > .fusion-column-wrapper {margin-right : 5.76%;margin-left : 5.76%;}}@media only screen and (max-width:767px) {.fusion-body .fusion-builder-column-13{width:100% !important;order : 0;}.fusion-builder-column-13 > .fusion-column-wrapper {margin-right : 1.92%;margin-left : 1.92%;}}<\/style><\/div><div class=\"fusion-layout-column fusion_builder_column fusion-builder-column-14 fusion_builder_column_1_3 1_3 fusion-flex-column AboutInfoBoxes\"><div class=\"fusion-column-wrapper lazyload fusion-flex-justify-content-flex-start fusion-content-layout-column\" style=\"background-position:left top;background-repeat:no-repeat;-webkit-background-size:cover;-moz-background-size:cover;-o-background-size:cover;background-size:cover;padding: 0px 0px 0px 0px;\" data-bg-url=\"https:\/\/depts.washington.edu\/impower22\/wp-content\/uploads\/2021\/10\/purple_card.png\" data-bg=\"https:\/\/depts.washington.edu\/impower22\/wp-content\/uploads\/2021\/10\/purple_card.png\"><div class=\"fusion-text fusion-text-14 WhiteText\"><h3>No guarantee<\/h3>\n<p>There is no guarantee that, if you are randomized to take islatravir, it will protect you against HIV<\/p>\n<\/div><\/div><style type=\"text\/css\">.fusion-body .fusion-builder-column-14{width:33.333333333333% !important;margin-top : 0px;margin-bottom : 35px;}.fusion-builder-column-14 > .fusion-column-wrapper {padding-top : 0px !important;padding-right : 0px !important;margin-right : 5.76%;padding-bottom : 0px !important;padding-left : 0px !important;margin-left : 5.76%;}@media only screen and (max-width:1024px) {.fusion-body .fusion-builder-column-14{width:33.333333333333% !important;order : 0;}.fusion-builder-column-14 > .fusion-column-wrapper {margin-right : 5.76%;margin-left : 5.76%;}}@media only screen and (max-width:767px) {.fusion-body .fusion-builder-column-14{width:100% !important;order : 0;}.fusion-builder-column-14 > .fusion-column-wrapper {margin-right : 1.92%;margin-left : 1.92%;}}<\/style><\/div><\/div><style type=\"text\/css\">.fusion-body .fusion-flex-container.fusion-builder-row-6{ padding-top : 0px;margin-top : 0px;padding-right : 0px;padding-bottom : 0px;margin-bottom : 0px;padding-left : 0px;}<\/style><\/div><div class=\"fusion-fullwidth fullwidth-box fusion-builder-row-7 fusion-flex-container SectionMargBottom nonhundred-percent-fullwidth non-hundred-percent-height-scrolling\" style=\"background-color: rgba(255,255,255,0);background-position: center center;background-repeat: no-repeat;border-width: 0px 0px 0px 0px;border-color:#e2e2e2;border-style:solid;\" id=\"QuoteBg\" ><div class=\"fusion-builder-row fusion-row fusion-flex-align-items-flex-start\" style=\"max-width:1210.56px;margin-left: calc(-4% \/ 2 );margin-right: calc(-4% \/ 2 );\"><div class=\"fusion-layout-column fusion_builder_column fusion-builder-column-15 fusion_builder_column_1_1 1_1 fusion-flex-column PurpleQuoteBg QuoteCol\"><div class=\"fusion-column-wrapper fusion-flex-justify-content-flex-start fusion-content-layout-column\" style=\"background-position:left top;background-repeat:no-repeat;-webkit-background-size:cover;-moz-background-size:cover;-o-background-size:cover;background-size:cover;padding: 0px 0px 0px 0px;\"><div class=\"fusion-text fusion-text-15 QuoteText WhiteText\"><h2>&#8220;Imagine the dream of being able to prevent HIV using an easy, discreet, convenient, once-a-month tablet becoming a reality. Let\u2019s be the ones who make this dream a reality!&#8221;<\/h2>\n<p>\u2014Dr. Pearl Selepe, Clinical Research Site Leader, The Aurum Institute<\/p>\n<\/div><\/div><style type=\"text\/css\">.fusion-body .fusion-builder-column-15{width:100% !important;margin-top : 0px;margin-bottom : 35px;}.fusion-builder-column-15 > .fusion-column-wrapper {padding-top : 0px !important;padding-right : 0px !important;margin-right : 1.92%;padding-bottom : 0px !important;padding-left : 0px !important;margin-left : 1.92%;}@media only screen and (max-width:1024px) {.fusion-body .fusion-builder-column-15{width:100% !important;order : 0;}.fusion-builder-column-15 > .fusion-column-wrapper {margin-right : 1.92%;margin-left : 1.92%;}}@media only screen and (max-width:767px) {.fusion-body .fusion-builder-column-15{width:100% !important;order : 0;}.fusion-builder-column-15 > .fusion-column-wrapper {margin-right : 1.92%;margin-left : 1.92%;}}<\/style><\/div><\/div><style type=\"text\/css\">.fusion-body .fusion-flex-container.fusion-builder-row-7{ padding-top : 0px;margin-top : 0px;padding-right : 0px;padding-bottom : 0px;margin-bottom : 0px;padding-left : 0px;}<\/style><\/div><div class=\"fusion-fullwidth fullwidth-box fusion-builder-row-8 fusion-flex-container SectionMargBottom nonhundred-percent-fullwidth non-hundred-percent-height-scrolling\" style=\"background-color: rgba(255,255,255,0);background-position: center center;background-repeat: no-repeat;border-width: 0px 0px 0px 0px;border-color:#e2e2e2;border-style:solid;\" ><div class=\"fusion-builder-row fusion-row fusion-flex-align-items-flex-start\" style=\"max-width:1210.56px;margin-left: calc(-4% \/ 2 );margin-right: calc(-4% \/ 2 );\"><div class=\"fusion-layout-column fusion_builder_column fusion-builder-column-16 fusion_builder_column_1_1 1_1 fusion-flex-column\" id=\"AboutToggles\"><div class=\"fusion-column-wrapper fusion-flex-justify-content-flex-start fusion-content-layout-column\" style=\"background-position:left top;background-repeat:no-repeat;-webkit-background-size:cover;-moz-background-size:cover;-o-background-size:cover;background-size:cover;padding: 0px 0px 0px 0px;\"><style type=\"text\/css\">#accordion-9-1 .fusion-panel:hover, #accordion-9-1 .fusion-panel.hover{ background-color: #f6f6f6 } #accordion-9-1 .fusion-panel { border-color:#002e5a; border-width:1px; background-color:#f6f6f6; }.fusion-accordian  #accordion-9-1 .panel-title a .fa-fusion-box{ color: #ffffff;}.fusion-accordian  #accordion-9-1 .panel-title a .fa-fusion-box:before{ font-size: 18px; width: 18px;}.fusion-accordian  #accordion-9-1.fusion-toggle-icon-right .fusion-toggle-heading{ margin-right: 36px;}.fusion-accordian  #accordion-9-1 .panel-title a{font-size:18px;}.fusion-accordian  #accordion-9-1 .fa-fusion-box { background-color: #002e5a;border-color: #002e5a;}.fusion-accordian  #accordion-9-1 .panel-title a:hover, #accordion-9-1 .fusion-toggle-boxed-mode:hover .panel-title a { color: #002e5a;}.fusion-accordian  #accordion-9-1 .panel-title .active .fa-fusion-box,.fusion-accordian  #accordion-9-1 .panel-title a:hover .fa-fusion-box { background-color: #002e5a!important;border-color: #002e5a!important;}<\/style><div class=\"accordian fusion-accordian\"><div class=\"panel-group fusion-toggle-icon-right\" id=\"accordion-9-1\"><div class=\"fusion-panel panel-default fusion-toggle-no-divider fusion-toggle-boxed-mode\"><div class=\"panel-heading\"><h4 class=\"panel-title toggle\"><a aria-expanded=\"false\" aria-controls=\"e087b92951a795e02\" role=\"button\" data-toggle=\"collapse\" data-parent=\"#accordion-9-1\" data-target=\"#e087b92951a795e02\" href=\"#e087b92951a795e02\"><span class=\"fusion-toggle-icon-wrapper\" aria-hidden=\"true\"><i class=\"fa-fusion-box\" aria-hidden=\"true\"><\/i><\/span><span class=\"fusion-toggle-heading\">Can you tell me more about PrEP?<\/span><\/a><\/h4><\/div><div id=\"e087b92951a795e02\" class=\"panel-collapse collapse \"><div class=\"panel-body toggle-content fusion-clearfix\">\n<p>About 1000 young women are infected with HIV every day\u2014and many of the young women who are getting infected live in Africa. We have made progress in HIV prevention but need additional prevention tools so that people have options and can choose what works best for them.<\/p>\n<p>Pre-exposure prophylaxis (PrEP) is when someone takes a medication to prepare their body to block HIV before being exposed. This medication lowers the chance of that person getting infected. It\u2019s like taking a pill to keep from getting malaria or using birth control to prevent pregnancy. It\u2019s the same idea.<\/p>\n<p>There is a PrEP pill available now (it has a couple of different names, including \u201cemtricitabine\/tenofovir\u201d or \u201cFTC\/TDF,\u201d also called \u201cTruvada\u201d), and it works very well. It is very effective in protecting against getting HIV when taken every day. Over 120 countries have adopted the World Health Organization PrEP guidelines, and access to PrEP is increasing globally. There are studies from Australia, Kenya, Uganda, and the United States that show it is possible to make an impact on the HIV epidemic on a population level if enough people get on PrEP and take it consistently.<\/p>\n<p>But for some people, it is hard to take a pill daily. Maybe someone is not able to take a pill every day, or maybe they don\u2019t want someone else finding a bottle of pills and wondering what they are for.<\/p>\n<p>This is why we are looking at PrEP drugs that last longer in the body. We want to find highly effective PrEP medications that are easier for people to use than a pill every day.<\/p>\n<\/div><\/div><\/div><div class=\"fusion-panel panel-default fusion-toggle-no-divider fusion-toggle-boxed-mode\"><div class=\"panel-heading\"><h4 class=\"panel-title toggle\"><a aria-expanded=\"false\" aria-controls=\"c99380a9f25d75e02\" role=\"button\" data-toggle=\"collapse\" data-parent=\"#accordion-9-1\" data-target=\"#c99380a9f25d75e02\" href=\"#c99380a9f25d75e02\"><span class=\"fusion-toggle-icon-wrapper\" aria-hidden=\"true\"><i class=\"fa-fusion-box\" aria-hidden=\"true\"><\/i><\/span><span class=\"fusion-toggle-heading\">Can you tell me more about the drug you are studying?<\/span><\/a><\/h4><\/div><div id=\"c99380a9f25d75e02\" class=\"panel-collapse collapse \"><div class=\"panel-body toggle-content fusion-clearfix\">\n<p>This study is testing a new HIV drug, called islatravir, for PrEP. Islatravir stays in the body for at least a month, much longer than a daily pill. It remains in the body in amounts that we think could prevent HIV. The IMPOWER study will look at how well islatravir works to prevent HIV and how safe it is, compared to the PrEP pill, called emtricitabine\/tenofovir (or FTC\/TDF), that has been shown to be safe and effective and is being used now.<\/p>\n<p>Women in the study will be seen in the study every month for up to 36 months. At each monthly visit, they will get an HIV test, a pregnancy test, and a month\u2019s supply of FTC\/TDF (or placebo, depending on what arm they are a part of), and a single dose of islatravir (or placebo). Every 3 months they will get blood tests for the kidneys and liver to learn more about the safety of these drugs.<\/p>\n<p>If women become pregnant during the study, they will learn which drug they were taking, and they will be offered the choice to continue taking their assigned drug or stop their assigned drug and switch to daily oral FTC\/TDF PrEP. During this time, women stay in the study and we will learn about the safety of islatravir and FTC\/TDF during pregnancy. With FTC\/TDF PrEP, it took several years for pregnant women to be able to access it after we knew that it worked because there was limited information about its safety in pregnancy. If islatravir works to prevent HIV and is safe to use, the data on islatravir during pregnancy that we get from IMPOWER could shorten the time from when we have results to when pregnant women could use islatravir.<\/p>\n<p>If women become infected with HIV, they will stop their study drug, be tested for the amount of virus in their blood and its sensitivity to specific antiretroviral medications, and be referred for treatment of HIV. The study staff will spend time with women who become infected with HIV during the study and offer counseling and other services to help them understand and adjust to their diagnoses.<\/p>\n<\/div><\/div><\/div><div class=\"fusion-panel panel-default fusion-toggle-no-divider fusion-toggle-boxed-mode\"><div class=\"panel-heading\"><h4 class=\"panel-title toggle\"><a aria-expanded=\"false\" aria-controls=\"bf5a3b1231240ffab\" role=\"button\" data-toggle=\"collapse\" data-parent=\"#accordion-9-1\" data-target=\"#bf5a3b1231240ffab\" href=\"#bf5a3b1231240ffab\"><span class=\"fusion-toggle-icon-wrapper\" aria-hidden=\"true\"><i class=\"fa-fusion-box\" aria-hidden=\"true\"><\/i><\/span><span class=\"fusion-toggle-heading\">Who is running this study?<\/span><\/a><\/h4><\/div><div id=\"bf5a3b1231240ffab\" class=\"panel-collapse collapse \"><div class=\"panel-body toggle-content fusion-clearfix\">\n<p>There are several partners for IMPOWER 22. Merck is the sponsor, has developed islatravir, and will work to have it approved for medical providers to prescribe if it is shown to be safe and effective. The Bill and Melinda Gates Foundation is supporting the study through a partnership with Merck and the University of Washington International Clinical Research Center (ICRC).<\/p>\n<\/div><\/div><\/div><div class=\"fusion-panel panel-default fusion-toggle-no-divider fusion-toggle-boxed-mode\"><div class=\"panel-heading\"><h4 class=\"panel-title toggle\"><a aria-expanded=\"false\" aria-controls=\"6d6906ef0b0e0a51c\" role=\"button\" data-toggle=\"collapse\" data-parent=\"#accordion-9-1\" data-target=\"#6d6906ef0b0e0a51c\" href=\"#6d6906ef0b0e0a51c\"><span class=\"fusion-toggle-icon-wrapper\" aria-hidden=\"true\"><i class=\"fa-fusion-box\" aria-hidden=\"true\"><\/i><\/span><span class=\"fusion-toggle-heading\">Have others reviewed this study to make sure I\u2019m protected?<\/span><\/a><\/h4><\/div><div id=\"6d6906ef0b0e0a51c\" class=\"panel-collapse collapse \"><div class=\"panel-body toggle-content fusion-clearfix\">\n<p>Yes, this study has been reviewed and approved by national drug authorities and local and national ethic and regulatory committees in the places where the study is being conducted. They looked carefully at the study design and the protection of participants like you.<\/p>\n<\/div><\/div><\/div><div class=\"fusion-panel panel-default fusion-toggle-no-divider fusion-toggle-boxed-mode\"><div class=\"panel-heading\"><h4 class=\"panel-title toggle\"><a aria-expanded=\"false\" aria-controls=\"5be544fc35cacf3ed\" role=\"button\" data-toggle=\"collapse\" data-parent=\"#accordion-9-1\" data-target=\"#5be544fc35cacf3ed\" href=\"#5be544fc35cacf3ed\"><span class=\"fusion-toggle-icon-wrapper\" aria-hidden=\"true\"><i class=\"fa-fusion-box\" aria-hidden=\"true\"><\/i><\/span><span class=\"fusion-toggle-heading\">How do you know if islatravir is safe and effective?<\/span><\/a><\/h4><\/div><div id=\"5be544fc35cacf3ed\" class=\"panel-collapse collapse \"><div class=\"panel-body toggle-content fusion-clearfix\">\n<p>An independent group of clinical research experts called the Data and Safety Monitoring Board (DSMB) review how the study is going. Importantly, the DSMB looks at the safety and efficacy data, which the study team is not allowed to see, so that the study team and investigators remain blinded to these key outcomes. The IMPOWER study will have DSMB reviews every six months. Participants will be informed if there is a change in risk in participating in the trial.<\/p>\n<\/div><\/div><\/div><div class=\"fusion-panel panel-default fusion-toggle-no-divider fusion-toggle-boxed-mode\"><div class=\"panel-heading\"><h4 class=\"panel-title toggle\"><a aria-expanded=\"false\" aria-controls=\"5645280aa09f510ef\" role=\"button\" data-toggle=\"collapse\" data-parent=\"#accordion-9-1\" data-target=\"#5645280aa09f510ef\" href=\"#5645280aa09f510ef\"><span class=\"fusion-toggle-icon-wrapper\" aria-hidden=\"true\"><i class=\"fa-fusion-box\" aria-hidden=\"true\"><\/i><\/span><span class=\"fusion-toggle-heading\">Is there any more information about this trial?<\/span><\/a><\/h4><\/div><div id=\"5645280aa09f510ef\" class=\"panel-collapse collapse \"><div class=\"panel-body toggle-content fusion-clearfix\">\n<p>ClinicalTrials.gov is a site that lists lots of different studies. The study\u2019s ClinicalTrials.gov Identifier number is NCT04644029 and it can be accessed online at <a href=\"https:\/\/clinicaltrials.gov\/ct2\/show\/NCT04644029\" target=\"_blank\" rel=\"noopener\">https:\/\/clinicaltrials.gov\/ct2\/show\/NCT04644029<\/a>, and you can find even more information about IMPOWER there.<\/p>\n<\/div><\/div><\/div><\/div><\/div><\/div><style type=\"text\/css\">.fusion-body .fusion-builder-column-16{width:100% !important;margin-top : 0px;margin-bottom : 35px;}.fusion-builder-column-16 > .fusion-column-wrapper {padding-top : 0px !important;padding-right : 0px !important;margin-right : 1.92%;padding-bottom : 0px !important;padding-left : 0px !important;margin-left : 1.92%;}@media only screen and (max-width:1024px) {.fusion-body .fusion-builder-column-16{width:100% !important;order : 0;}.fusion-builder-column-16 > .fusion-column-wrapper {margin-right : 1.92%;margin-left : 1.92%;}}@media only screen and (max-width:767px) {.fusion-body .fusion-builder-column-16{width:100% !important;order : 0;}.fusion-builder-column-16 > .fusion-column-wrapper {margin-right : 1.92%;margin-left : 1.92%;}}<\/style><\/div><\/div><style type=\"text\/css\">.fusion-body .fusion-flex-container.fusion-builder-row-8{ padding-top : 0px;margin-top : 0px;padding-right : 0px;padding-bottom : 0px;margin-bottom : 0px;padding-left : 0px;}<\/style><\/div><div class=\"fusion-fullwidth fullwidth-box fusion-builder-row-9 fusion-flex-container SectionMargBottom nonhundred-percent-fullwidth non-hundred-percent-height-scrolling\" style=\"background-color: rgba(255,255,255,0);background-position: center center;background-repeat: no-repeat;border-width: 0px 0px 0px 0px;border-color:#e2e2e2;border-style:solid;\" id=\"QuoteBg\" ><div class=\"fusion-builder-row fusion-row fusion-flex-align-items-flex-start\" style=\"max-width:1210.56px;margin-left: calc(-4% \/ 2 );margin-right: calc(-4% \/ 2 );\"><div class=\"fusion-layout-column fusion_builder_column fusion-builder-column-17 fusion_builder_column_1_1 1_1 fusion-flex-column GoldQuoteBg QuoteCol\"><div class=\"fusion-column-wrapper fusion-flex-justify-content-flex-start fusion-content-layout-column\" style=\"background-position:left top;background-repeat:no-repeat;-webkit-background-size:cover;-moz-background-size:cover;-o-background-size:cover;background-size:cover;padding: 0px 0px 0px 0px;\"><div class=\"fusion-text fusion-text-16 QuoteText WhiteText\"><h2>\u201cFewer and less frequent tablets are always easier\u2014imagine that with HIV PrEP!&#8221;<\/h2>\n<p>\u2014 Margaret Kasaro, , MBChB, MSc, Research Assistant Professor, Global Women\u2019s Health, UNC<\/p>\n<\/div><\/div><style type=\"text\/css\">.fusion-body .fusion-builder-column-17{width:100% !important;margin-top : 0px;margin-bottom : 35px;}.fusion-builder-column-17 > .fusion-column-wrapper {padding-top : 0px !important;padding-right : 0px !important;margin-right : 1.92%;padding-bottom : 0px !important;padding-left : 0px !important;margin-left : 1.92%;}@media only screen and (max-width:1024px) {.fusion-body .fusion-builder-column-17{width:100% !important;order : 0;}.fusion-builder-column-17 > .fusion-column-wrapper {margin-right : 1.92%;margin-left : 1.92%;}}@media only screen and (max-width:767px) {.fusion-body .fusion-builder-column-17{width:100% !important;order : 0;}.fusion-builder-column-17 > .fusion-column-wrapper {margin-right : 1.92%;margin-left : 1.92%;}}<\/style><\/div><\/div><style type=\"text\/css\">.fusion-body .fusion-flex-container.fusion-builder-row-9{ padding-top : 0px;margin-top : 0px;padding-right : 0px;padding-bottom : 0px;margin-bottom : 0px;padding-left : 0px;}<\/style><\/div><\/p>\n","protected":false},"excerpt":{"rendered":"","protected":false},"author":6,"featured_media":0,"parent":0,"menu_order":10,"comment_status":"closed","ping_status":"closed","template":"100-width.php","meta":{"footnotes":""},"class_list":["post-9","page","type-page","status-publish","hentry"],"_links":{"self":[{"href":"https:\/\/depts.washington.edu\/impower22\/wp-json\/wp\/v2\/pages\/9","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/depts.washington.edu\/impower22\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/depts.washington.edu\/impower22\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/depts.washington.edu\/impower22\/wp-json\/wp\/v2\/users\/6"}],"replies":[{"embeddable":true,"href":"https:\/\/depts.washington.edu\/impower22\/wp-json\/wp\/v2\/comments?post=9"}],"version-history":[{"count":1,"href":"https:\/\/depts.washington.edu\/impower22\/wp-json\/wp\/v2\/pages\/9\/revisions"}],"predecessor-version":[{"id":118,"href":"https:\/\/depts.washington.edu\/impower22\/wp-json\/wp\/v2\/pages\/9\/revisions\/118"}],"wp:attachment":[{"href":"https:\/\/depts.washington.edu\/impower22\/wp-json\/wp\/v2\/media?parent=9"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}