Institute for Stem Cell & Regenerative Medicine

at the University of Washington

Recent Research

Abundance of Drug Transporters in the Human Kidney Cortex as Quantified by Quantitative Targeted Proteomics
Drug Metabolism & Disposition, December 2016


Carotid plaque fissure: An underestimated source of intraplaque hemorrhage
Atherosclerosis, November 2016



Characterization of atherosclerotic disease in thoracic aorta: A 3D, multicontrast vessel wall imaging study
European Journal of Radiology, November 2016



Depth-resolved 3D visualization of coronary microvasculature with optical microangiography
Physics in Medicine and Biology, November 2016


Engineered Microvessels for the Study of Human Disease
Journal of Biomechanical Engineering, November 2016


Liver and Kidney on Chips: Microphysiological Models to Understand Transporter Function
Clinical Pharmacology & Therapeutics, November 2016


Mapping 3D genome architecture through in situ DNase Hi-C
Nature Protocol, November 2016


Nicorandil, a Nitric Oxide Donor and ATP-Sensitive Potassium Channel Opener, Protects Against Dystrophin-Deficient Cardiomyopathy
Journal of Cardiovascular Pharmacology and Therapeutics, November 2016


Transporter Expression in Liver Tissue from Subjects with Alcoholic or Hepatitis C Cirrhosis Quantified by Targeted Quantitative Proteomics
Drug Metabolism & Disposition, November 2016


Vessel wall imaging for intracranial vascular disease evaluation
Journal of NeuroInterventional Surgery, November 2016



CaMKII induces permeability transition through Drp1 phosphorylation during chronic β-AR stimulation
Nature Communications, October 2016

Decellularized Human Kidney Cortex Hydrogels Enhance Kidney Microvascular Endothelial Cell Maturation and Quiescence
Tissue Engineering Part A, October 2016


Imaging to Assess the Effect of Anti-Inflammatory Therapy in Aortic and Carotid Atherosclerosis
Journal of the American College of Cardiology, October 2016


Invited commentary
Journal of Vascular Surgery, October 2016



Nonmuscle Myosin IIA Regulates Platelet Contractile Forces Through Rho Kinase and Myosin Light-Chain Kinase
Journal of Biomechanical Engineering, October 2016



Species Differences in Microsomal Oxidation and Glucuronidation of 4-Ipomeanol: Relationship to Target Organ Toxicity
Drug Metabolism & Disposition, October 2016


The microRNA expression profile of mouse Müller glia in vivo and in vitro
Nature Scientific Reports, October 2016


Wnt/β-catenin signaling promotes self-renewal and inhibits the primed state transition in naïve human embryonic stem cells
PNAS, October 2016


Cholesterol Efflux Capacity and Subclasses of HDL Particles in Healthy Women Transitioning Through Menopause
The Journal of Clinical Endocrinology & Metabolism, September 2016


Conversion of Prostate Adenocarcinoma to Small Cell Carcinoma-Like by Reprogramming
Journal of Cellular Physiology, September 2016


Development of a microphysiological model of human kidney proximal tubule function
Kidney International, September 2016


Muscular dystrophy in a dish: engineered human skeletal muscle mimetics for disease modeling and drug discovery
Drug Discovery Today, September 2016


Normalization of NAD+ Redox Balance as a Therapy for Heart Failure
Circulation, September 2016


SCAP/SREBP pathway is required for the full steroidogenic response to cyclic AMP
PNAS, September 2016


Wnt/β-catenin signaling promotes regeneration after adult zebrafish spinal cord injury
Biochemical and Biophysical Research Communications, September 2016


XLinkDB 2.0: integrated, large-scale structural analysis of protein crosslinking data
Bioinformatics, September 2016