Institute for Stem Cell & Regenerative Medicine

at the University of Washington

Recent Research

Guanidinylated block copolymers for gene transfer: A comparison with amine-based materials for in vitro and in vivo gene transfer efficiency
Biomaterials, June 2015


O6-methylguanine-DNA methyltransferase activity is associated with response to alkylating agent therapy and with MGMT promoter methylation in glioblastoma and anaplastic glioma
BBA Clinical, June 2015

A photoreversible protein-patterning approach for guiding stem cell fate in three-dimensional gels
Nature Materials, May 2015


Ascending KLFs in cardiovascular biology
Trends in Cardiovascular Medicine, May 2015


Dual energy computed tomography quantification of carotid plaques calcification: comparison between monochromatic and polychromatic energies with pathology correlation
European Radiology, May 2015

Endothelium and NOTCH specify and amplify aorta-gonad-mesonephros-derived hematopoietic stem cells
The Journal of Clinical Investigation, May 2015


Identification of a prg4-expressing articular cartilage progenitor cell population in mice
Arthritis & Rheumatology, May 2015


Multivalent display of pendant pro-apoptotic peptides increases cytotoxic activity
Journal of Controlled Release, May 2015


Outcomes after stent graft therapy for dissection-related aneurysmal degeneration in the descending thoracic aorta
Journal of Vascular Surgery, May 2015


G-CSF Priming, clofarabine, and high dose cytarabine (GCLAC) for upfront treatment of acute myeloid leukemia, advanced myelodysplastic syndrome or advanced myeloproliferative neoplasm
American Journal of Hematology, April 2015

JALA Special Issue: Microengineered Cell- and Tissue-Based Assays for Drug Screening and Toxicology Applications
Journal of Laboratory Automation, April 2015


LINGO-1 Protein Interacts with the p75 Neurotrophin Receptor in Intracellular Membrane Compartments
The Journal of Biological Chemistry, April 2015


Mechanisms of Bone Marrow−Derived Cell Therapy in Ischemic Cardiomyopathy With Left Ventricular Assist Device Bridge to Transplant
Journal of the American College of Cardiology, April 2015


Phosphorylation of Ser283 enhances the stiffness of the tropomyosin head-to-tail overlap domain
Archives of Biochemistry and Biophysics, April 2015


Probing the Protein Interaction Network of Pseudomonas aeruginosa Cells by Chemical Cross-Linking Mass Spectrometry
Structure, April 2015


Relation of Clinical Response and Minimal Residual Disease and Their Prognostic Impact on Outcome in Acute Myeloid Leukemia
Journal of Clinical Oncology, April 2015


The mitochondrial permeability transition pore regulates endothelial bioenergetics and angiogenesis
Circulation Research, April 2015


The proteomic landscape of triple-negative breast cancer
Cell Reports, April 2015


Cadherins in Islet β-Cells: More Than Meets the Eye
Diabetes, March 2015


Combined effects of substrate topography and stiffness on endothelial cytokine and chemokine secretion
ACS Applied Materials & Interfaces, March 2015


Control of the interface between heterotypic cell populations reveals the mechanism of intercellular transfer of signaling proteins
Integrative Biology, March 2015


Correlation between peripheral blood and bone marrow regarding FLT3-ITD and NPM1 mutational status in patients with acute myeloid leukemia
Haematologica, March 2015


Epigenomics of autoimmune diseases
Immunology & Cell Biology, March 2015


Exposure to phthalates affects calcium handling and intercellular connectivity of human stem cell-derived cardiomyocytes
PLOS ONE, March 2015

LINGO-1 promotes lysosomal degradation of amyloid-β protein
                 Pathobiology of Aging & Age-related Diseases, March 2015


Serum amyloid A and inflammation in diabetic kidney disease and podocytes
Laboratory Investigation, March 2015


Small HDL Promotes Cholesterol Efflux by the ABCA1 Pathway in Macrophages: Implications for Therapies Targeted to HDL
Circulation Research, March 2015