The monthly seminar, “Toward Precision Medicine for Alzheimer’s Disease,” offers a forum for investigators from across the School of Medicine, University of Washington, and partner organizations (Sage Bionetworks, Allen Institute, Seattle Institute for Biomedical Research, etc.) to discuss research projects that align with the UW ADRC’s theme of precision medicine for AD. The focus of each meeting is on identifying, describing, and detecting pathophysiologic heterogeneity in AD and related degenerative diseases, with an eye towards defining rationale and targets for treatment and enhancing the innovation and impact of our work going forward.
March 2, 2020: Spero Manson, PhD. Distinguished Professor, Public Health and Psychiatry Director, Centers for American Indian and Alaska Native Health University of Colorado Denver’s Anschutz Medical Center Colorado School of Public Health Title: Native Peoples and the All of Us Research Program: Inclusion, Collaboration, Governance, and Benefit (VIDEO) (Summary PDF)
Febrary 2020 Pilot Project Update: Robert J. Freishtat, M.D., M.P.H., Senior Investigator in the Center for Genetic Medicine of the Children’s Research Institute, Professor in Pediatrics and Genomics and Precision Medicine at The George Washington University School of Medicine and Health Sciences. Obesity and Dementia: MicroRNAs from Adipocyte-derived Small Extracellular Vesicles are associated with Neurodegenerative Pathways. (Summary PDF)
February 3, 2020 Dr. Julie Saugstad, PhD, Professor, Oregon Health & Sciences University. Title: MicroRNA Biomarkers for AD: Performance in Mild Cognitive Impairment and Traumatic Brain Injury (Summary PDF)
December 2, 2019 Dr. Ed Lein, PhD, Investigator, Allen Institute for Brain Science, Affiliate Professor, UW Dept. of Neurological Surgery. Title: From A Human Brain Cell Census Towards Precision Medicine
November 4, 2019 Dr. Ellen Wijsman, PhD, Professor, Dept. of Medical Genetics. Title: From families to causal variants in the Alzheimer's Disease Sequencing Project: what have we learned from whole-genome sequencing and what are the challenges.
October 28, 2019 Dr. Olav Andersen, PhD, Dept. of Biomedicine-Medical Biochemistry, Aarhus University, Denmark. Title: The Alzheimer’s disease gene SORL1: Discovery of a novel exon implying synaptic functions besides AAP trafficking. (Summary PDF)
June 3, 2019, 4-5pm: Speaker: Pierre D. Mourad, PhD, Professor, Division of Engineering and Mathematics. Title: Towards use of transcranial, near-diagnostic ultrasound to treat dementia (Summary PDF)
December 2018 - May 2019 - no meetings
November 5, 2018: Speaker: Dr. Debby Tsuang, Professor, Dept. of Psychiatry and Behavioral Sciences, UW/ Adjunct Professor, Epidemiology/ Director, Geriatric Research, Education, and Clinical Center (GRECC), VA Puget Sound Heath Care System. Genetics of Alzheimer's Disease: a Public Health Perspective Location: Location: Rm 812, Bldg 1, VA Puget Sound, 4-5pm.
October 1, 2018 Speaker: Dr. Elaine Peskind, Professor, Dept. of Psychiatry and Behavioral Sciences, UW. Drain the Swamp: Prazosin for Prevention of Neurodegeneration. UW Health Sciences Building RR202, 4-5pm. (Summary PDF)
September 10, 2018 4-5pm - Speaker: Shelly Erickson, PhD, Research Assist. Professor, Division of Gerontology, UW. Serum amyloid A proteins and their interactions with the blood-brain barrier in Alzheimer's disease. Location: Rm 812, Bldg 1, VA Puget Sound. (Summary PDF)
July - August 2018 - No meetings
June 4th, 2018 - Speaker: Dr. Melissa Barker-Haliski, PhD, Research Assistant Professor, UW Dept. of Pharmacy. Presenilin 2 variants age-dependently alter susceptibility to chronic seizures and anticonvulsant drug response. Location: UW Health Sciences Building RR202, 4-5pm
May 2018 - No meeting
April 2, 2018: Speaker: Jing Zhang, M.D., Ph.D. Professor of Pathology, Shaw Endowed Chair in Neuropathology, Adjunct Professor of Neurology, Ophthalmology and Oral Health Sciences, University of Washington. - Blood-based but CNS specific biomarkers for Alzheimer's disease and Parkinson's disease. Location: Research & Training Building, Rm 109/113, 4-5pm (Summary PDF)
March 15, 2018: Speakers: Haakon Nygaard, Fipke Professor in Alzheimer’s Research, UBC / Matthew Farrer, Professor, Dept. of Medical Genetics, UBC. UWMC, RR-202, 3-4pm. (No summary available.)
December 4, 2017 4:00-5:00 pm. Turner Auditorium, D-209 Health Sciences Building - Dr. Andy Teich, MD, PhD, Assistant Professor of Pathology & Cell Biology, Columbia University/ Neuropathology Core Co-Lead, Columbia University ADRC/ Co-Director New York Brain Bank - A Systems Biology Approach to Discovering Novel Drivers of Disease in AD. (Summary PDF)
November 6, 2017 - Brenda Degerald, Senior Array and Genotyping Specialist, Illumina & Jonathan Bibliowicz, PhD, Senior Sequencing Specialist, Illumina - Genomic Solutions for the Study of Complex Neurodegenerative Disorders. A special seminar to hear about and discuss the newest technology from Illumina (Summary PDF)
October 2, 2017 - Dr. Gwenn Garden, Md, PhD, Professor, UW Department of Neurology, ADRC Affiliate Member - Microglia in AD Pathogenesis (PDF)
September 11, 2017 - Dr. Brian Kraemer, PhD, Research Associate Professor, Gerontology & Geriatric Medicine, UW, Investigator, VA Puget Sound Health Care System/ ADRC Affiliate Member - MSUT2: a novel therapeutic target for Alzheimer’s Disease (Summary PDF)
August 7th, 2017 - Elizabeth Blue, UW Division of Medical Genetics/ ADRC Affiliate Member - Variants regulating NCSTN and ZBTB4 are associated with age-at-onset of Alzheimer’s disease (Summary PDF)
July 2017 - No meeting
June 2017- No meeting
May 2017 - Ben Logsdon, Senior Scientist, Sage Bionetworks/ ADRC Affiliate Member - Transcriptomic Network Prioritization of Alzheimer’s Disease Drivers (PDF)
April 2017 - No meeting
March 2017 - Daniel Promislow, Professor, Departments of Pathology and Biology, University of Washington - Systems biology of neurodegenerative disease in the fruit fly, Drosophila melanogaster (Summary PDF)
February 2017 - No meeting
January 2017 - Matt Kaeberlein, Professor, UW Department of Pathology, ADRC Project 1 Leader - Preventing Alzheimer’s disease by targeting the hallmarks of aging (PDF)
December 2016 - Paul Crane, Professor of Medicine, UW Medicine/ ADRC Affiliate Member - Cognitive testing data to sub-group people with Alzheimer's disease (PDF)
November 2016 - Jessica Young, Assistant Professor, UW Department of Pathology/ ADRC Affiliate Member - Probing cellular mechanisms of sporadic Alzheimer’s disease risk using patient stem cells (Summary PDF)
For questions about this symposium, please contact Annika Noreen at firstname.lastname@example.org. For questions about this archive, contact Genevieve Wanucha at email@example.com.