MsFLASH: Living a Healthy Menopause

Susan D Reed, MD, MPH, Principal Investigator

This is a new application from the Menopause Strategies: Finding Lasting Answers for Symptoms and Health (MsFLASH) Clinical Trials network. Here we propose to conduct a large multicenter trial comparing two common treatments, a vaginal hormone pill and an over-the-counter gel, with placebo to evaluate their effects on bothersome vaginal symptoms and sexual function, and to create a biorepository of specimens for future translational, mechanistic research on the etiology of vaginal symptoms. We also propose to build a set of comprehensive, evidence-based, user friendly and widely available multi-media materials to reach women and providers with the newest trial results evaluating the effectiveness of treatments ranging from hormones to complementary and alternative therapies to behavioral interventions for relief of hot flashes, vaginal, sleep, mood and pain symptoms. These aims are geared to transforming the evidence-base and resources available to aging women for navigating this life stage.

Funding Source: Fred Hutchinson Cancer Research Center – NIH
End Date: 3-31-2020