{"id":10025,"date":"2021-05-26T15:03:15","date_gmt":"2021-05-26T22:03:15","guid":{"rendered":"https:\/\/depts.washington.edu\/pandemicalliance\/?p=10025"},"modified":"2021-05-27T15:04:07","modified_gmt":"2021-05-27T22:04:07","slug":"estimating-infectiousness-throughout-sars-cov-2-infection-course","status":"publish","type":"post","link":"https:\/\/depts.washington.edu\/pandemicalliance\/2021\/05\/26\/estimating-infectiousness-throughout-sars-cov-2-infection-course\/","title":{"rendered":"Estimating Infectiousness throughout SARS-CoV-2 Infection Course"},"content":{"rendered":"<ul>\n<li style=\"font-weight: 400\"><span style=\"font-weight: 400\">An analysis of 936,423 SARS-CoV-2 RT-PCR-positive samples from hospitalized and non-hospitalized persons in Germany found that high viral loads (&gt; 10<\/span><span style=\"font-weight: 400\">9 <\/span><span style=\"font-weight: 400\">copies per swab) were found in 8% of subjects, 1\/3 of whom were pre-symptomatic, asymptomatic, or mildly symptomatic. The mean number of days from onset of viral shedding to peak viral load was 4.3. Additionally, persons infected with the B.1.1.7 variant had a 1.05 higher mean log<\/span><span style=\"font-weight: 400\">10<\/span><span style=\"font-weight: 400\"> viral load and a 2.6-fold higher probability of cell culture replication than persons infected with non-B.1.1.7 strains. These results indicate that some individuals with mild or no symptoms may be as infectious as persons with severe infection.<\/span><\/li>\n<\/ul>\n<p><i><span style=\"font-weight: 400\">Jones et al. (May 25, 2021). Estimating Infectiousness throughout SARS-CoV-2 Infection Course. Science. <\/span><\/i><a href=\"https:\/\/doi.org\/10.1126\/science.abi5273\"><span style=\"font-weight: 400\">https:\/\/doi.org\/10.1126\/science.abi5273<\/span><\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>An analysis of 936,423 SARS-CoV-2 RT-PCR-positive samples from hospitalized and non-hospitalized persons in Germany found that high viral loads (&gt; 109 copies per swab) were found in 8% of subjects, 1\/3 of whom were pre-symptomatic, asymptomatic, or mildly symptomatic. The mean number of days from onset of viral shedding to peak viral load was 4.3&#8230;.<\/p>\n<div><a class=\"more\" href=\"https:\/\/depts.washington.edu\/pandemicalliance\/2021\/05\/26\/estimating-infectiousness-throughout-sars-cov-2-infection-course\/\">Read more<\/a><\/div>\n","protected":false},"author":8,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":"","_links_to":"","_links_to_target":""},"categories":[6],"tags":[34,38,141],"topic":[21],"class_list":["post-10025","post","type-post","status-publish","format-standard","hentry","category-article-summary","tag-clinical-characteristics","tag-transmission","tag-variant","topic-transmission"],"_links":{"self":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts\/10025","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/users\/8"}],"replies":[{"embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/comments?post=10025"}],"version-history":[{"count":1,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts\/10025\/revisions"}],"predecessor-version":[{"id":10026,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts\/10025\/revisions\/10026"}],"wp:attachment":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/media?parent=10025"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/categories?post=10025"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/tags?post=10025"},{"taxonomy":"topic","embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/topic?post=10025"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}