{"id":10062,"date":"2021-05-27T15:28:05","date_gmt":"2021-05-27T22:28:05","guid":{"rendered":"https:\/\/depts.washington.edu\/pandemicalliance\/?p=10062"},"modified":"2021-05-28T15:28:43","modified_gmt":"2021-05-28T22:28:43","slug":"post-vaccination-sars-cov-2-infection-risk-factors-and-illness-profile-in-a-prospective-observational-community-based-case-control-study","status":"publish","type":"post","link":"https:\/\/depts.washington.edu\/pandemicalliance\/2021\/05\/27\/post-vaccination-sars-cov-2-infection-risk-factors-and-illness-profile-in-a-prospective-observational-community-based-case-control-study\/","title":{"rendered":"Post-Vaccination SARS-CoV-2 Infection Risk Factors and Illness Profile in a Prospective Observational Community-Based Case-Control Study"},"content":{"rendered":"<ul>\n<li style=\"font-weight: 400\"><i><span style=\"font-weight: 400\">[Pre-print, not peer-reviewed]<\/span><\/i><span style=\"font-weight: 400\"> Breakthrough SARS-CoV-2 infections after at least 14 days following the first dose of the Oxford-AstraZeneca or Pfizer-BioNTech vaccines were less likely among those with healthier lifestyle factors. Findings were based on a case-control study of 2,394 individuals with a breakthrough infection matched 1:1 by age, sex, and other potential confounders to other vaccinated individuals in the UK. Individuals living in the most deprived areas had increased risk of breakthrough infection, as well as older adults aged \u226560 years. Frailty was associated with a 3-fold higher risk of breakthrough infection. In a separate analysis matching individuals with breakthrough infection to a control group of unvaccinated adults with infection, vaccinated individuals reported fewer symptoms and had 64% lower risk of hospitalization.<\/span><\/li>\n<\/ul>\n<p><i><span style=\"font-weight: 400\">Antonelli et al.\u00a0(May 26, 2021). Post-Vaccination SARS-CoV-2 Infection Risk Factors and Illness Profile in a Prospective Observational Community-Based Case-Control Study. Pre-print downloaded May 27 from <\/span><\/i><a href=\"https:\/\/doi.org\/10.1101\/2021.05.24.21257738\"><span style=\"font-weight: 400\">https:\/\/doi.org\/10.1101\/2021.05.24.21257738<\/span><\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>[Pre-print, not peer-reviewed] Breakthrough SARS-CoV-2 infections after at least 14 days following the first dose of the Oxford-AstraZeneca or Pfizer-BioNTech vaccines were less likely among those with healthier lifestyle factors. Findings were based on a case-control study of 2,394 individuals with a breakthrough infection matched 1:1 by age, sex, and other potential confounders to other&#8230;<\/p>\n<div><a class=\"more\" href=\"https:\/\/depts.washington.edu\/pandemicalliance\/2021\/05\/27\/post-vaccination-sars-cov-2-infection-risk-factors-and-illness-profile-in-a-prospective-observational-community-based-case-control-study\/\">Read more<\/a><\/div>\n","protected":false},"author":8,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":"","_links_to":"","_links_to_target":""},"categories":[6],"tags":[147],"topic":[31],"class_list":["post-10062","post","type-post","status-publish","format-standard","hentry","category-article-summary","tag-vaccination","topic-vaccines-and-immunity"],"_links":{"self":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts\/10062","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/users\/8"}],"replies":[{"embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/comments?post=10062"}],"version-history":[{"count":1,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts\/10062\/revisions"}],"predecessor-version":[{"id":10063,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts\/10062\/revisions\/10063"}],"wp:attachment":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/media?parent=10062"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/categories?post=10062"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/tags?post=10062"},{"taxonomy":"topic","embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/topic?post=10062"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}