{"id":10097,"date":"2021-05-28T10:26:49","date_gmt":"2021-05-28T17:26:49","guid":{"rendered":"https:\/\/depts.washington.edu\/pandemicalliance\/?p=10097"},"modified":"2021-06-01T10:27:34","modified_gmt":"2021-06-01T17:27:34","slug":"the-humoral-response-to-the-bnt162b2-vaccine-in-hemodialysis-patients","status":"publish","type":"post","link":"https:\/\/depts.washington.edu\/pandemicalliance\/2021\/05\/28\/the-humoral-response-to-the-bnt162b2-vaccine-in-hemodialysis-patients\/","title":{"rendered":"The Humoral Response to the BNT162b2 Vaccine in Hemodialysis Patients"},"content":{"rendered":"<ul>\n<li style=\"font-weight: 400\"><i><span style=\"font-weight: 400\">[Pre-print, not peer-reviewed]<\/span><\/i><span style=\"font-weight: 400\"> Anti-SARS-CoV-2 spike antibodies were detected in 80% of chronic hemodialysis patients (n=66) 28 days after a single dose of the Pfizer-BioNTech vaccine in a cohort study in Toronto, Canada. However, only 23% mounted a robust response defined by exceeding the median level of anti-spike antibodies observed in serum of healthy convalescent controls (n=35). Anti-spike antibodies were detected in 96% of patients receiving two doses (n=76), but only 72% mounted a robust response. Similar patterns were observed for detectable anti-receptor binding domain (RBD) antibodies.<\/span><\/li>\n<\/ul>\n<p><i><span style=\"font-weight: 400\">Yau et al.\u00a0(May 27, 2021). The Humoral Response to the BNT162b2 Vaccine in Hemodialysis Patients. Pre-print downloaded May 28 from <\/span><\/i><a href=\"https:\/\/doi.org\/10.1101\/2021.05.24.21257425\"><span style=\"font-weight: 400\">https:\/\/doi.org\/10.1101\/2021.05.24.21257425<\/span><\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>[Pre-print, not peer-reviewed] Anti-SARS-CoV-2 spike antibodies were detected in 80% of chronic hemodialysis patients (n=66) 28 days after a single dose of the Pfizer-BioNTech vaccine in a cohort study in Toronto, Canada. However, only 23% mounted a robust response defined by exceeding the median level of anti-spike antibodies observed in serum of healthy convalescent controls&#8230;<\/p>\n<div><a class=\"more\" href=\"https:\/\/depts.washington.edu\/pandemicalliance\/2021\/05\/28\/the-humoral-response-to-the-bnt162b2-vaccine-in-hemodialysis-patients\/\">Read more<\/a><\/div>\n","protected":false},"author":8,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":"","_links_to":"","_links_to_target":""},"categories":[6],"tags":[201,32],"topic":[31],"class_list":["post-10097","post","type-post","status-publish","format-standard","hentry","category-article-summary","tag-immune-response","tag-immunity","topic-vaccines-and-immunity"],"_links":{"self":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts\/10097","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/users\/8"}],"replies":[{"embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/comments?post=10097"}],"version-history":[{"count":1,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts\/10097\/revisions"}],"predecessor-version":[{"id":10098,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts\/10097\/revisions\/10098"}],"wp:attachment":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/media?parent=10097"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/categories?post=10097"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/tags?post=10097"},{"taxonomy":"topic","embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/topic?post=10097"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}