{"id":10115,"date":"2021-06-01T11:20:29","date_gmt":"2021-06-01T18:20:29","guid":{"rendered":"https:\/\/depts.washington.edu\/pandemicalliance\/?p=10115"},"modified":"2021-06-03T11:21:13","modified_gmt":"2021-06-03T18:21:13","slug":"prior-covid-19-protects-against-reinfection-even-in-the-absence-of-detectable-antibodies","status":"publish","type":"post","link":"https:\/\/depts.washington.edu\/pandemicalliance\/2021\/06\/01\/prior-covid-19-protects-against-reinfection-even-in-the-absence-of-detectable-antibodies\/","title":{"rendered":"Prior COVID-19 Protects against Reinfection, Even in the Absence of Detectable Antibodies"},"content":{"rendered":"<ul>\n<li style=\"font-weight: 400\"><span style=\"font-weight: 400\">Risk of SARS-CoV-2 infection in the UK between August 2020 and January 2021 was 80% lower among individuals with lab-confirmed infection but later testing antibody-negative (i.e. RNA-positive antibody-negative) compared to individuals who did not have infection (no test or RNA-negative and antibody-negative) during March to July 2020, according to an analysis of datasets obtained from 4 UK laboratories. Only 2 reinfections (&gt;90 days after initial infection) occurred among 224 RNA-positive antibody-negative individuals (0.9%) compared to 2,054 second-wave infections in the 47,139 patients with no prior infection (4.4%). Risk of SARS-CoV-2 infection in RNA-positive antibody-negative individuals was similar to a subset of 2,087 patients who were RNA-positive and antibody-positive. As the study is based on laboratory datasets, the authors caution that testing may have been event-driven compared with datasets from routine screening.<\/span><\/li>\n<\/ul>\n<p><i><span style=\"font-weight: 400\">Breathnach et al.\u00a0(May 2021). Prior COVID-19 Protects against Reinfection, Even in the Absence of Detectable Antibodies. Journal of Infection. <\/span><\/i><a href=\"https:\/\/doi.org\/10.1016\/j.jinf.2021.05.024\"><span style=\"font-weight: 400\">https:\/\/doi.org\/10.1016\/j.jinf.2021.05.024<\/span><\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Risk of SARS-CoV-2 infection in the UK between August 2020 and January 2021 was 80% lower among individuals with lab-confirmed infection but later testing antibody-negative (i.e. RNA-positive antibody-negative) compared to individuals who did not have infection (no test or RNA-negative and antibody-negative) during March to July 2020, according to an analysis of datasets obtained from&#8230;<\/p>\n<div><a class=\"more\" href=\"https:\/\/depts.washington.edu\/pandemicalliance\/2021\/06\/01\/prior-covid-19-protects-against-reinfection-even-in-the-absence-of-detectable-antibodies\/\">Read more<\/a><\/div>\n","protected":false},"author":8,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":"","_links_to":"","_links_to_target":""},"categories":[6],"tags":[32,221],"topic":[31],"class_list":["post-10115","post","type-post","status-publish","format-standard","hentry","category-article-summary","tag-immunity","tag-re-infection","topic-vaccines-and-immunity"],"_links":{"self":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts\/10115","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/users\/8"}],"replies":[{"embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/comments?post=10115"}],"version-history":[{"count":1,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts\/10115\/revisions"}],"predecessor-version":[{"id":10116,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts\/10115\/revisions\/10116"}],"wp:attachment":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/media?parent=10115"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/categories?post=10115"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/tags?post=10115"},{"taxonomy":"topic","embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/topic?post=10115"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}