{"id":10121,"date":"2021-06-01T11:23:08","date_gmt":"2021-06-01T18:23:08","guid":{"rendered":"https:\/\/depts.washington.edu\/pandemicalliance\/?p=10121"},"modified":"2021-06-03T11:23:57","modified_gmt":"2021-06-03T18:23:57","slug":"correlation-of-vaccine-elicited-antibody-levels-and-neutralizing-activities-against-sars-cov-2-and-its-variants","status":"publish","type":"post","link":"https:\/\/depts.washington.edu\/pandemicalliance\/2021\/06\/01\/correlation-of-vaccine-elicited-antibody-levels-and-neutralizing-activities-against-sars-cov-2-and-its-variants\/","title":{"rendered":"Correlation of Vaccine-Elicited Antibody Levels and Neutralizing Activities against SARS-CoV-2 and Its Variants"},"content":{"rendered":"<ul>\n<li style=\"font-weight: 400\"><i><span style=\"font-weight: 400\">[Pre-print, not peer-reviewed]<\/span><\/i><span style=\"font-weight: 400\"> Analysis of sera from individuals fully vaccinated with the Pfizer-BioNTech (n=30) and Moderna (n=19) vaccines \u226522 days after the second dose showed that neutralizing activity against pseudoviruses bearing mutated spike proteins from variants of concern was detectable in all participants but was reduced by 7-10 fold against the B.1.351 variant. Anti-SARS-CoV-2 IgG antibody levels correlated well with neutralizing titers for the wild-type strain as well as for variants of concern.\u00a0<\/span><\/li>\n<\/ul>\n<p><i><span style=\"font-weight: 400\">Liu et al.\u00a0(May 31, 2021). Correlation of Vaccine-Elicited Antibody Levels and Neutralizing Activities against SARS-CoV-2 and Its Variants. Pre-print downloaded Jun 1 from <\/span><\/i><a href=\"https:\/\/doi.org\/10.1101\/2021.05.31.445871\"><span style=\"font-weight: 400\">https:\/\/doi.org\/10.1101\/2021.05.31.445871<\/span><\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>[Pre-print, not peer-reviewed] Analysis of sera from individuals fully vaccinated with the Pfizer-BioNTech (n=30) and Moderna (n=19) vaccines \u226522 days after the second dose showed that neutralizing activity against pseudoviruses bearing mutated spike proteins from variants of concern was detectable in all participants but was reduced by 7-10 fold against the B.1.351 variant. Anti-SARS-CoV-2 IgG&#8230;<\/p>\n<div><a class=\"more\" href=\"https:\/\/depts.washington.edu\/pandemicalliance\/2021\/06\/01\/correlation-of-vaccine-elicited-antibody-levels-and-neutralizing-activities-against-sars-cov-2-and-its-variants\/\">Read more<\/a><\/div>\n","protected":false},"author":8,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":"","_links_to":"","_links_to_target":""},"categories":[6],"tags":[67,33],"topic":[31],"class_list":["post-10121","post","type-post","status-publish","format-standard","hentry","category-article-summary","tag-antibodies","tag-vaccines","topic-vaccines-and-immunity"],"_links":{"self":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts\/10121","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/users\/8"}],"replies":[{"embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/comments?post=10121"}],"version-history":[{"count":1,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts\/10121\/revisions"}],"predecessor-version":[{"id":10122,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts\/10121\/revisions\/10122"}],"wp:attachment":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/media?parent=10121"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/categories?post=10121"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/tags?post=10121"},{"taxonomy":"topic","embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/topic?post=10121"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}