{"id":10168,"date":"2021-06-03T15:03:58","date_gmt":"2021-06-03T22:03:58","guid":{"rendered":"https:\/\/depts.washington.edu\/pandemicalliance\/?p=10168"},"modified":"2021-06-04T15:04:38","modified_gmt":"2021-06-04T22:04:38","slug":"structural-analysis-of-the-novel-variants-of-sars-cov-2-and-forecasting-in-north-america","status":"publish","type":"post","link":"https:\/\/depts.washington.edu\/pandemicalliance\/2021\/06\/03\/structural-analysis-of-the-novel-variants-of-sars-cov-2-and-forecasting-in-north-america\/","title":{"rendered":"Structural Analysis of the Novel Variants of SARS-CoV-2 and Forecasting in North America"},"content":{"rendered":"<ul>\n<li style=\"font-weight: 400\"><span style=\"font-weight: 400\">A forecasting model incorporating North American prevalence of SARS-CoV-2 variants of concern from the genome database GISAID suggests that the B.1.1.7 variant could become dominant (&gt;60% of sequenced strains) by summer 2021 but would sharply decrease in frequency when 75% of the population is immune through vaccination or natural infection due to its high binding affinity to the neutralizing antibody CV30 (~90%). Though the B.1.351, B.1.617, and P.1 variants remain in low frequencies, they may each consist of up to 5% of strains even after high vaccination coverage due to their lower binding affinity to neutralizing antibodies (~70%).<\/span><\/li>\n<\/ul>\n<p><i><span style=\"font-weight: 400\">Quinonez et al.\u00a0(May 17, 2021). Structural Analysis of the Novel Variants of SARS-CoV-2 and Forecasting in North America. Viruses. <\/span><\/i><a href=\"https:\/\/doi.org\/10.3390\/v13050930\"><span style=\"font-weight: 400\">https:\/\/doi.org\/10.3390\/v13050930<\/span><\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>A forecasting model incorporating North American prevalence of SARS-CoV-2 variants of concern from the genome database GISAID suggests that the B.1.1.7 variant could become dominant (&gt;60% of sequenced strains) by summer 2021 but would sharply decrease in frequency when 75% of the population is immune through vaccination or natural infection due to its high binding&#8230;<\/p>\n<div><a class=\"more\" href=\"https:\/\/depts.washington.edu\/pandemicalliance\/2021\/06\/03\/structural-analysis-of-the-novel-variants-of-sars-cov-2-and-forecasting-in-north-america\/\">Read more<\/a><\/div>\n","protected":false},"author":8,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":"","_links_to":"","_links_to_target":""},"categories":[6],"tags":[33,159],"topic":[24],"class_list":["post-10168","post","type-post","status-publish","format-standard","hentry","category-article-summary","tag-vaccines","tag-variants","topic-geographic-spread"],"_links":{"self":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts\/10168","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/users\/8"}],"replies":[{"embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/comments?post=10168"}],"version-history":[{"count":1,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts\/10168\/revisions"}],"predecessor-version":[{"id":10169,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts\/10168\/revisions\/10169"}],"wp:attachment":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/media?parent=10168"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/categories?post=10168"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/tags?post=10168"},{"taxonomy":"topic","embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/topic?post=10168"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}