{"id":10247,"date":"2021-06-07T10:58:31","date_gmt":"2021-06-07T17:58:31","guid":{"rendered":"https:\/\/depts.washington.edu\/pandemicalliance\/?p=10247"},"modified":"2021-06-08T10:59:13","modified_gmt":"2021-06-08T17:59:13","slug":"plasma-ace2-predicts-outcome-of-covid-19-in-hospitalized-patients","status":"publish","type":"post","link":"https:\/\/depts.washington.edu\/pandemicalliance\/2021\/06\/07\/plasma-ace2-predicts-outcome-of-covid-19-in-hospitalized-patients\/","title":{"rendered":"Plasma ACE2 Predicts Outcome of COVID-19 in Hospitalized Patients"},"content":{"rendered":"<ul>\n<li style=\"font-weight: 400\"><span style=\"font-weight: 400\">A<\/span><span style=\"font-weight: 400\">mong patients with COVID-19 (n=306), high plasma levels of angiotensin converting enzyme 2 (ACE2) at hospital admission were associated with increased illness severity within 28 days (OR = 1.8), and plasma ACE2 was significantly higher among patients with hypertension. Circulating ACE2 was also significantly higher in patients with COVID-19 with pre-existing heart conditions and kidney disease. The authors suggest that ACE2 may predict <\/span><span style=\"font-weight: 400\">COVID-19<\/span> <span style=\"font-weight: 400\">disease outcome.<\/span><\/li>\n<\/ul>\n<p><i><span style=\"font-weight: 400\">Kragstrup et al.\u00a0(June 4, 2021). Plasma ACE2 Predicts Outcome of COVID-19 in Hospitalized Patients. PLOS ONE. <\/span><\/i><a href=\"https:\/\/doi.org\/10.1371\/journal.pone.0252799\"><span style=\"font-weight: 400\">https:\/\/doi.org\/10.1371\/journal.pone.0252799<\/span><\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Among patients with COVID-19 (n=306), high plasma levels of angiotensin converting enzyme 2 (ACE2) at hospital admission were associated with increased illness severity within 28 days (OR = 1.8), and plasma ACE2 was significantly higher among patients with hypertension. Circulating ACE2 was also significantly higher in patients with COVID-19 with pre-existing heart conditions and kidney&#8230;<\/p>\n<div><a class=\"more\" href=\"https:\/\/depts.washington.edu\/pandemicalliance\/2021\/06\/07\/plasma-ace2-predicts-outcome-of-covid-19-in-hospitalized-patients\/\">Read more<\/a><\/div>\n","protected":false},"author":8,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":"","_links_to":"","_links_to_target":""},"categories":[6],"tags":[34],"topic":[20],"class_list":["post-10247","post","type-post","status-publish","format-standard","hentry","category-article-summary","tag-clinical-characteristics","topic-clinical-characteristics-and-health-care-setting"],"_links":{"self":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts\/10247","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/users\/8"}],"replies":[{"embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/comments?post=10247"}],"version-history":[{"count":1,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts\/10247\/revisions"}],"predecessor-version":[{"id":10248,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts\/10247\/revisions\/10248"}],"wp:attachment":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/media?parent=10247"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/categories?post=10247"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/tags?post=10247"},{"taxonomy":"topic","embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/topic?post=10247"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}