{"id":10249,"date":"2021-06-07T10:59:20","date_gmt":"2021-06-07T17:59:20","guid":{"rendered":"https:\/\/depts.washington.edu\/pandemicalliance\/?p=10249"},"modified":"2021-06-08T11:00:02","modified_gmt":"2021-06-08T18:00:02","slug":"the-role-of-hiv-infection-in-the-clinical-spectrum-of-covid-19-a-population-based-cohort-analysis-based-on-us-national-covid-cohort-collaborative-n3c-enclave-data","status":"publish","type":"post","link":"https:\/\/depts.washington.edu\/pandemicalliance\/2021\/06\/07\/the-role-of-hiv-infection-in-the-clinical-spectrum-of-covid-19-a-population-based-cohort-analysis-based-on-us-national-covid-cohort-collaborative-n3c-enclave-data\/","title":{"rendered":"The Role of HIV Infection in the Clinical Spectrum of COVID-19 a Population-Based Cohort Analysis Based on US National COVID Cohort Collaborative (N3C) Enclave Data"},"content":{"rendered":"<ul>\n<li style=\"font-weight: 400\"><i><span style=\"font-weight: 400\">[Pre-print, not peer-reviewed]<\/span><\/i> <span style=\"font-weight: 400\">A study using electronic health record data from 54 clinical sites in the National COVID Cohort Collaborative found that people living with HIV (PLWH, n=13,170) had a higher risk of COVID-19 death and hospitalization after adjusting for age and sex.<\/span> <span style=\"font-weight: 400\">The associations were attenuated, but remained significant, after adjusting for smoking status, BMI, and comorbidities (death aOR = 1.4, hospitalization = 1.2). PLWH were more likely to have severe <\/span><span style=\"font-weight: 400\">COVID-19 <\/span><span style=\"font-weight: 400\">when only controlling for demographics, smoking, and BMI, although the estimated risk was obviated after controlling for comorbidities. <\/span><span style=\"font-weight: 400\">Analysis for effect modification found<\/span><span style=\"font-weight: 400\"> that the <\/span><span style=\"font-weight: 400\">HIV-associated <\/span><span style=\"font-weight: 400\">risk was higher among older <\/span><span style=\"font-weight: 400\">people<\/span><span style=\"font-weight: 400\">, males, and Black\/African American individuals.\u00a0<\/span><\/li>\n<\/ul>\n<p><i><span style=\"font-weight: 400\">Yang et al.\u00a0(June 6, 2021). The Role of HIV Infection in the Clinical Spectrum of COVID-19 a Population-Based Cohort Analysis Based on US National COVID Cohort Collaborative (N3C) Enclave Data. Pre-print downloaded Jun 7 from <\/span><\/i><a href=\"https:\/\/doi.org\/10.1101\/2021.06.03.21258324\"><span style=\"font-weight: 400\">https:\/\/doi.org\/10.1101\/2021.06.03.21258324<\/span><\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>[Pre-print, not peer-reviewed] A study using electronic health record data from 54 clinical sites in the National COVID Cohort Collaborative found that people living with HIV (PLWH, n=13,170) had a higher risk of COVID-19 death and hospitalization after adjusting for age and sex. The associations were attenuated, but remained significant, after adjusting for smoking status,&#8230;<\/p>\n<div><a class=\"more\" href=\"https:\/\/depts.washington.edu\/pandemicalliance\/2021\/06\/07\/the-role-of-hiv-infection-in-the-clinical-spectrum-of-covid-19-a-population-based-cohort-analysis-based-on-us-national-covid-cohort-collaborative-n3c-enclave-data\/\">Read more<\/a><\/div>\n","protected":false},"author":8,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":"","_links_to":"","_links_to_target":""},"categories":[6],"tags":[34,46],"topic":[20],"class_list":["post-10249","post","type-post","status-publish","format-standard","hentry","category-article-summary","tag-clinical-characteristics","tag-risk-factors","topic-clinical-characteristics-and-health-care-setting"],"_links":{"self":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts\/10249","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/users\/8"}],"replies":[{"embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/comments?post=10249"}],"version-history":[{"count":1,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts\/10249\/revisions"}],"predecessor-version":[{"id":10250,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/posts\/10249\/revisions\/10250"}],"wp:attachment":[{"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/media?parent=10249"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/categories?post=10249"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/tags?post=10249"},{"taxonomy":"topic","embeddable":true,"href":"https:\/\/depts.washington.edu\/pandemicalliance\/wp-json\/wp\/v2\/topic?post=10249"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}